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Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
Schafflick, David, Xu, Chenling A., Hartlehnert, Maike, Cole, Michael, Schulte-Mecklenbeck, Andreas, Lautwein, Tobias, Wolbert, Jolien, Heming, Michael, Meuth, Sven G., Kuhlmann, Tanja, Gross, Catharina C., Wiendl, Heinz, Yosef, Nir, Meyer zu Horste, Gerd
Published in Nature communications (14.01.2020)
Published in Nature communications (14.01.2020)
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Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity
Burkett, Patrick R., Meyer zu Horste, Gerd, Kuchroo, Vijay K.
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity
Wang, Chao, Yosef, Nir, Gaublomme, Jellert, Wu, Chuan, Lee, Youjin, Clish, Clary B., Kaminski, Jim, Xiao, Sheng, Zu Horste, Gerd Meyer, Pawlak, Mathias, Kishi, Yasuhiro, Joller, Nicole, Karwacz, Katarzyna, Zhu, Chen, Ordovas-Montanes, Maria, Madi, Asaf, Wortman, Ivo, Miyazaki, Toru, Sobel, Raymond A., Park, Hongkun, Regev, Aviv, Kuchroo, Vijay K.
Published in Cell (03.12.2015)
Published in Cell (03.12.2015)
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RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression
Meyer zu Horste, Gerd, Wu, Chuan, Wang, Chao, Cong, Le, Pawlak, Mathias, Lee, Youjin, Elyaman, Wassim, Xiao, Sheng, Regev, Aviv, Kuchroo, Vijay K.
Published in Cell reports (Cambridge) (12.07.2016)
Published in Cell reports (Cambridge) (12.07.2016)
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Bcl6 controls meningeal Th17–B cell interaction in murine neuroinflammation
Hartlehnert, Maike, Börsch, Anna-Lena, Li, Xiaolin, Burmeister, Miriam, Gerwien, Hanna, Schafflick, David, Heming, Michael, Lu, I-Na, Narayanan, Venu, Strecker, Jan-Kolja, Kolz, Anna, Peters, Anneli, Wu, Gregory F., Wiendl, Heinz, Sorokin, Lydia, Horste, Gerd Meyer zu
Published in Proceedings of the National Academy of Sciences (07.09.2021)
Published in Proceedings of the National Academy of Sciences (07.09.2021)
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Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges
Schafflick, David, Wolbert, Jolien, Heming, Michael, Thomas, Christian, Hartlehnert, Maike, Börsch, Anna-Lena, Ricci, Alessio, Martín-Salamanca, Sandra, Li, Xiaolin, Lu, I-Na, Pawlak, Mathias, Minnerup, Jens, Strecker, Jan-Kolja, Seidenbecher, Thomas, Meuth, Sven G., Hidalgo, Andres, Liesz, Arthur, Wiendl, Heinz, Meyer zu Horste, Gerd
Published in Nature neuroscience (01.09.2021)
Published in Nature neuroscience (01.09.2021)
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Charcot-Marie-Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential
Noack, Rebecca, Frede, Svenja, Albrecht, Philipp, Henke, Nadine, Pfeiffer, Annika, Knoll, Katrin, Dehmel, Thomas, Meyer zu Hörste, Gerd, Stettner, Mark, Kieseier, Bernd C., Summer, Holger, Golz, Stefan, Kochanski, Andrzej, Wiedau-Pazos, Martina, Arnold, Susanne, Lewerenz, Jan, Methner, Axel
Published in Human molecular genetics (01.01.2012)
Published in Human molecular genetics (01.01.2012)
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Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
Meyer zu Horste, Gerd, Przybylski, Dariusz, Schramm, Markus A., Wang, Chao, Schnell, Alexandra, Lee, Youjin, Sobel, Raymond, Regev, Aviv, Kuchroo, Vijay K.
Published in Immunity (Cambridge, Mass.) (20.03.2018)
Published in Immunity (Cambridge, Mass.) (20.03.2018)
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Schwann cells promote post-traumatic nerve inflammation and neuropathic pain through MHC class II
Hartlehnert, Maike, Derksen, Angelika, Hagenacker, Tim, Kindermann, David, Schäfers, Maria, Pawlak, Mathias, Kieseier, Bernd C., Meyer zu Horste, Gerd
Published in Scientific reports (02.10.2017)
Published in Scientific reports (02.10.2017)
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Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses
Räuber, Saskia, Heming, Michael, Repple, Jonathan, Ruland, Tillmann, Kuelby, Rebecca, Schulte-Mecklenbeck, Andreas, Gross, Catharina C., Arolt, Volker, Baune, Bernhard, Hahn, Tim, Dannlowski, Udo, Meuth, Sven G., Melzer, Nico, Wiendl, Heinz, Meyer zu Hörste, Gerd
Published in Molecular psychiatry (01.12.2021)
Published in Molecular psychiatry (01.12.2021)
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Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment
Lu, I-Na, Cheung, Phyllis Fung-Yi, Heming, Michael, Thomas, Christian, Giglio, Giovanni, Leo, Markus, Erdemir, Merve, Wirth, Timo, König, Simone, Dambietz, Christine A., Schroeter, Christina B., Nelke, Christopher, Siveke, Jens T., Ruck, Tobias, Klotz, Luisa, Haider, Carmen, Höftberger, Romana, Kleinschnitz, Christoph, Wiendl, Heinz, Hagenacker, Tim, Meyer zu Horste, Gerd
Published in Nature communications (15.05.2024)
Published in Nature communications (15.05.2024)
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Novel pathomechanisms in inflammatory neuropathies
Schafflick, David, Kieseier, Bernd C., Wiendl, Heinz, Meyer zu Horste, Gerd
Published in Journal of neuroinflammation (28.11.2017)
Published in Journal of neuroinflammation (28.11.2017)
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Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma
Heming, Michael, Haessner, Svea, Wolbert, Jolien, Lu, I-Na, Li, Xiaolin, Brokinkel, Benjamin, Müther, Michael, Holling, Markus, Stummer, Walter, Thomas, Christian, Schulte-Mecklenbeck, Andreas, de Faria, Flavia, Stoeckius, Marlon, Hailfinger, Stephan, Lenz, Georg, Kerl, Kornelius, Wiendl, Heinz, Meyer zu Hörste, Gerd, Grauer, Oliver M.
Published in Genome medicine (24.09.2022)
Published in Genome medicine (24.09.2022)
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A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis
Ostkamp, Patrick, Deffner, Marie, Schulte-Mecklenbeck, Andreas, Wünsch, Christian, Lu, I-Na, Wu, Gregory F, Goelz, Susan, De Jager, Philip L, Kuhlmann, Tanja, Gross, Catharina C, Klotz, Luisa, Meyer Zu Hörste, Gerd, Wiendl, Heinz, Schneider-Hohendorf, Tilman, Schwab, Nicholas
Published in Science translational medicine (30.11.2022)
Published in Science translational medicine (30.11.2022)
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Deciphering immune mechanisms in chronic inflammatory demyelinating polyneuropathies
Wolbert, Jolien, Cheng, Mandy I., Horste, Gerd Meyer zu, Su, Maureen A.
Published in JCI insight (13.02.2020)
Published in JCI insight (13.02.2020)
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Stroke induces disease-specific myeloid cells in the brain parenchyma and pia
Beuker, Carolin, Schafflick, David, Strecker, Jan-Kolja, Heming, Michael, Li, Xiaolin, Wolbert, Jolien, Schmidt-Pogoda, Antje, Thomas, Christian, Kuhlmann, Tanja, Aranda-Pardos, Irene, A-Gonzalez, Noelia, Kumar, Praveen Ashok, Werner, Yves, Kilic, Ertugrul, Hermann, Dirk M., Wiendl, Heinz, Stumm, Ralf, Meyer zu Hörste, Gerd, Minnerup, Jens
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
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Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease
Speicher, Anna M., Korn, Lisanne, Csatári, Júlia, Gonzalez-Cano, Laura, Heming, Michael, Thomas, Christian, Schroeter, Christina B., Schafflick, David, Li, Xiaolin, Gola, Lukas, Engler, Alexander, Kaehne, Thilo, Vallier, Ludovic, Meuth, Sven G., Hörste, Gerd Meyer zu, Kovac, Stjepana, Wiendl, Heinz, Schöler, Hans R., Pawlowski, Matthias
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2022)
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Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A)
Sereda, Michael W, Meyer zu Hörste, Gerd, Suter, Ueli, Uzma, Naureen, Nave, Klaus-Armin
Published in Nature medicine (01.12.2003)
Published in Nature medicine (01.12.2003)
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Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound
Janoschka, Claudia, Lindner, Maren, Koppers, Nils, Starost, Laura, Liebmann, Marie, Eschborn, Melanie, Schneider-Hohendorf, Tilman, Windener, Farina, Schafflick, David, Fleck, Ann-Katrin, Koch, Kathrin, Deffner, Marie, Schwarze, Anna-Sophie, Schulte-Mecklenbeck, Andreas, Metz, Imke, Meuth, Sven G., Gross, Catharina C., Meyer zu Hörste, Gerd, Schwab, Nicholas, Kuhlmann, Tanja, Wiendl, Heinz, Stoll, Monika, Klotz, Luisa
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2023)
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