Search Results - "Zou, Gen"
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Efficient genome editing in filamentous fungi via an improved CRISPR‐Cas9 ribonucleoprotein method facilitated by chemical reagents
Published in Microbial biotechnology (01.11.2021)“…We report an optimized genome editing approach for filamentous fungi based on RNPs facilitated by adding chemical reagents. We increased the gene editing…”
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Synthetic biology enables mushrooms to meet emerging sustainable challenges
Published in Frontiers in microbiology (2024)“…With the increasing sustainability challenges, synthetic biology is offering new possibilities for addressing the emerging problems through the cultivation and…”
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Accelerating the integration of ChatGPT and other large‐scale AI models into biomedical research and healthcare
Published in MedComm - Future medicine (01.06.2023)“…Large‐scale artificial intelligence (AI) models such as ChatGPT have the potential to improve performance on many benchmarks and real‐world tasks. However, it…”
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Editorial: Fungal green biotechnology and biomanufacturing
Published in Frontiers in microbiology (29.11.2023)
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Current Advances in the Functional Genes of Edible and Medicinal Fungi: Research Techniques, Functional Analysis, and Prospects
Published in Journal of fungi (Basel) (01.05.2024)“…Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal…”
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NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis
Published in Frontiers in immunology (22.09.2021)“…Endometriosis is an estrogen-dependent gynecological disease. The pathogenesis of endometriosis remains controversial, although it is generally accepted that…”
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Use of CRISPR‐Cas tools to engineer Trichoderma species
Published in Microbial biotechnology (01.10.2022)“…Given their lignocellulose degradability and biocontrol activities, fungi of the ubiquitously distributed genus Trichoderma have multiple industrial and…”
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Development and validation of MRI-based radiomics model for clinical symptom stratification of extrinsic adenomyosis
Published in Annals of medicine (Helsinki) (01.12.2025)“…Extrinsic adenomyosis exhibits heterogeneous clinical symptoms, with pain being more commonly reported. The relationship between magnetic resonance imaging…”
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Genomic and Secretomic Analyses Reveal Unique Features of the Lignocellulolytic Enzyme System of Penicillium decumbens
Published in PloS one (01.02.2013)“…Many Penicillium species could produce extracellular enzyme systems with good lignocellulose hydrolysis performance. However, these species and their enzyme…”
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Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing
Published in Cell & bioscience (26.05.2021)“…Endometriosis is a refractory and recurrent disease and it affects nearly 10% of reproductive-aged women and 40% of infertile patients. The commonly accepted…”
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Cross-Kingdom DNA Methylation Dynamics: Comparative Mechanisms of 5mC/6mA Regulation and Their Implications in Epigenetic Disorders
Published in Biology (Basel, Switzerland) (24.04.2025)“…DNA methylation, a cornerstone of epigenetic regulation, governs critical biological processes including transcriptional modulation, genomic imprinting, and…”
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World Health Organization’s first-ever release of a fungal priority pathogens list: A reply action proposal for the prevention and treatment of fungal pathogens
Published in Eco-Environment & Health (01.06.2023)“…[Display omitted] •The information about World Health Organization’s fungal priority pathogens list was introduced•The main reply action for fungal pathogens…”
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CRISPR/Cas9-mediated efficient genome editing via blastospore-based transformation in entomopathogenic fungus Beauveria bassiana
Published in Scientific reports (03.04.2017)“…Beauveria bassiana is an environmentally friendly alternative to chemical insecticides against various agricultural insect pests and vectors of human diseases…”
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A novel transcription factor specifically regulates GH11 xylanase genes in Trichoderma reesei
Published in Biotechnology for biofuels (03.08.2017)“…The filamentous fungus is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the accessibility of…”
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Association of Myometrial Invasion With Lymphovascular Space Invasion, Lymph Node Metastasis, Recurrence, and Overall Survival in Endometrial Cancer: A Meta-Analysis of 79 Studies With 68,870 Patients
Published in Frontiers in oncology (21.10.2021)“…Myometrial invasion has been demonstrated to correlate to clinicopathological characteristics and prognosis in endometrial cancer. However, not all the studies…”
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Improvement of cellulase activity in Trichoderma reesei by heterologous expression of a beta-glucosidase gene from Penicillium decumbens
Published in Enzyme and microbial technology (10.09.2011)“…Trichoderma reesei is a well-known cellulase producer and widely applied in enzyme industry. To increase its ability to efficiently decompose cellulose, the…”
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GPR30-mediated non-classic estrogen pathway in mast cells participates in endometriosis pain via the production of FGF2
Published in Frontiers in immunology (08.02.2023)“…Pain is one of the main clinical symptoms of endometriosis, but its underlying mechanism is still not clear. Recent studies have shown that the secretory…”
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Probiotic Fermentation of Defatted Cottonseed Meal for Sustainable Foods and Non-Food Applications
Published in Microorganisms (Basel) (29.04.2025)“…Cottonseed is a valuable source of high-quality proteins and oils. Defatted cottonseed meal (DCSM), a by-product of cottonseed oil extraction, holds…”
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Botrytis cinerea Transcription Factor BcXyr1 Regulates (Hemi-)Cellulase Production and Fungal Virulence
Published in mSystems (20.12.2022)“…PCWDEs are considered important components of the virulence arsenal of necrotrophic plant pathogens. However, despite intensive research, the role of PCWDEs in…”
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Advancements and Future Directions in Yellow Rice Wine Production Research
Published in Fermentation (Basel) (01.01.2024)“…Yellow rice wine is a traditional fermented beverage in China. The microorganisms in the brewing process play a crucial role in shaping the composition and…”
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