PCC0208027, a novel tyrosine kinase inhibitor, inhibits tumor growth of NSCLC by targeting EGFR and HER2 aberrations
Dong, Qiuju, Yu, Pengfei, Ye, Liang, Zhang, Jianzhao, Wang, Hongbo, Zou, Fangxia, Tian, Jingwei, Kurihara, Hiroshi
Published in Scientific reports (05.04.2019)
Published in Scientific reports (05.04.2019)
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(+)-9-Trifluoroethoxy-α-Dihydrotetrabenazine as a Highly Potent Vesicular Monoamine Transporter 2 Inhibitor for Tardive Dyskinesia
Wang, Wenyan, Du, Guangying, Lin, Shilan, Liu, Jing, Yang, Huijie, Yu, Dawei, Ye, Liang, Zou, Fangxia, Wang, Hongbo, Zhang, Rui, Tian, Jingwei
Published in Frontiers in pharmacology (07.12.2021)
Published in Frontiers in pharmacology (07.12.2021)
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Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective
Ma, Tianfang, Zou, Fangxia, Pusch, Stefan, Xu, Yungen, von Deimling, Andreas, Zha, Xiaoming
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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PCC0208023, a potent SHP2 allosteric inhibitor, imparts an antitumor effect against KRAS mutant colorectal cancer
Chen, Xiao, Zou, Fangxia, Hu, Zhengping, Du, Guangying, Yu, Pengfei, Wang, Wenyan, Wang, Hongbo, Ye, Liang, Tian, Jingwei
Published in Toxicology and applied pharmacology (01.07.2020)
Published in Toxicology and applied pharmacology (01.07.2020)
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Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors
Yang, Yifei, Yu, Dawei, Zhu, Xiaoyin, Du, Guangying, Wang, Wenyan, Zou, Fangxia, Wang, Hongbo, Zhang, Rui, Ye, Liang, Tian, Jingwei
Published in European journal of medicinal chemistry (15.11.2021)
Published in European journal of medicinal chemistry (15.11.2021)
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Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor
Ye, Liang, Yang, Yifei, Li, Chunmei, Zhang, Jianzhao, Wang, Wenyan, Ma, Mingxu, Xu, Hengwei, Zhang, Wenjing, Zou, Fangxia, Hu, Zhengping, Wang, Hongbo, Tian, Jingwei
Published in European journal of medicinal chemistry (05.09.2023)
Published in European journal of medicinal chemistry (05.09.2023)
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Discovery of the thieno[2,3-d]pyrimidine-2,4-dione derivative 21a: A potent and orally bioavailable gonadotropin-releasing hormone receptor antagonist
Zou, Fangxia, Wang, Yao, Yu, Dawei, Liu, Chunjiao, Lu, Jing, Zhao, Min, Ma, Mingxu, Wang, Wenyan, Jiang, Wanglin, Gao, Yonglin, Zhang, Rui, Zhang, Jianzhao, Ye, Liang, Tian, Jingwei
Published in European journal of medicinal chemistry (15.11.2022)
Published in European journal of medicinal chemistry (15.11.2022)
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Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT(2)(A )receptor antagonists/inverse agonists
Ma, Mingxu, Yang, Yifei, Du, Guangying, Dai, Yusen, Zhu, Xiaoyin, Wang, Wenyan, Xu, Hengwei, Zhang, Jianzhao, Zheng, Lixia, Zou, Fangxia, Yang, Huijie, Liu, Bin, Liu, Wanhui, Ye, Liang, Zhang, Rui, Tian, Jingwei
Published in European journal of medicinal chemistry (15.04.2022)
Published in European journal of medicinal chemistry (15.04.2022)
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Journal Article
Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1
Ma, Tianfang, Zou, Fangxia, Pusch, Stefan, Yang, Lijun, Zhu, Qihua, Xu, Yungen, Gu, Yueqing, von Deimling, Andreas, Zha, Xiaoming
Published in Bioorganic & medicinal chemistry (15.12.2017)
Published in Bioorganic & medicinal chemistry (15.12.2017)
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Journal Article
Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT2A receptor antagonists/inverse agonists
Ma, Mingxu, Yang, Yifei, Du, Guangying, Dai, Yusen, Zhu, Xiaoyin, Wang, Wenyan, Xu, Hengwei, Zhang, Jianzhao, Zheng, Lixia, Zou, Fangxia, Yang, Huijie, Liu, Bin, Liu, Wanhui, Ye, Liang, Zhang, Rui, Tian, Jingwei
Published in European journal of medicinal chemistry (15.04.2022)
Published in European journal of medicinal chemistry (15.04.2022)
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Journal Article
Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening
Zou, Fangxia, Pusch, Stefan, Hua, Jie, Ma, Tianfang, Yang, Lijun, Zhu, Qihua, Xu, Yungen, Gu, Yueqing, von Deimling, Andreas, Zha, Xiaoming
Published in Bioorganic & medicinal chemistry letters (01.02.2018)
Published in Bioorganic & medicinal chemistry letters (01.02.2018)
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Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1
Lu, Jing, Lei, Hui, Bai, Xinfa, Wang, Wenyan, Liu, Chunjiao, Yang, Yifei, Zou, Fangxia, Wang, Lin, Wang, Yunjie, Du, Guangying, Wang, Xin, Sun, Cuicui, Yu, Lisha, Ma, Mingxu, Ye, Liang, Wang, Hongbo, Tian, Jingwei, Zhang, Jianzhao
Published in Bioorganic chemistry (01.10.2023)
Published in Bioorganic chemistry (01.10.2023)
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Identification of novel MEK1 inhibitors by pharmacophore and docking based virtual screening
Zou, Fangxia, Yang, Yifei, Ma, Tianfang, Xi, Jiayue, Zhou, Jinpei, Zha, Xiaoming
Published in Medicinal chemistry research (01.04.2017)
Published in Medicinal chemistry research (01.04.2017)
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Identification of a novel selective inhibitor of mutant isocitrate dehydrogenase 1 at allosteric site by docking-based virtual screening
Zou, Fangxia, Pusch, Stefan, Eisel, Jessica, Ma, Tianfang, Zhu, Qihua, Deng, Dawei, Gu, Yueqing, Xu, Yungen, von Deimling, Andreas, Zha, Xiaoming
Published in RSC advances (2016)
Published in RSC advances (2016)
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Identification of new non-steroidal TGR5 agonists using virtual screening with combined pharmacophore models
Zhou, Chen, Zou, Fangxia, Xu, Yungen, Zhang, Luyong, Zha, Xiaoming
Published in Medicinal chemistry research (01.06.2015)
Published in Medicinal chemistry research (01.06.2015)
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Combined pharmacophore models as virtual screening protocol against BRD4(1) inhibitor
Yang, Yifei, Zou, Fangxia, Zhao, Leilei, Cheng, Yulan, Zha, Xiaoming, Zhang, Huibin, Zhou, Jinpei
Published in Medicinal chemistry research (01.04.2016)
Published in Medicinal chemistry research (01.04.2016)
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Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT 2A receptor antagonists/inverse agonists
Ma, Mingxu, Yang, Yifei, Du, Guangying, Dai, Yusen, Zhu, Xiaoyin, Wang, Wenyan, Xu, Hengwei, Zhang, Jianzhao, Zheng, Lixia, Zou, Fangxia, Yang, Huijie, Liu, Bin, Liu, Wanhui, Ye, Liang, Zhang, Rui, Tian, Jingwei
Published in European journal of medicinal chemistry (15.04.2022)
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Published in European journal of medicinal chemistry (15.04.2022)
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TIAN JINGWEI, ZHANG RUI, DU GUANGYING, YE LIANG, ZOU FANGXIA, LIU ZONGLIANG, YU DAWEI, CUI BO
Year of Publication 21.03.2022
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Year of Publication 21.03.2022
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Design, synthesis and biological activity of N-(3-substituted-phenyl)benzenesulfonamides as selective and reversible LSD1 inhibitors
Zha, Xiaoming, Wu, Liming, Xu, Siyuan, Zou, Fangxia, Xi, Jiayue, Ma, Tianfang, Liu, Rongfeng, Liu, Yu-Chih, Deng, Dawei, Gu, Yueqing, Zhou, Jinpei, Lan, Fei
Published in Medicinal chemistry research (01.12.2016)
Published in Medicinal chemistry research (01.12.2016)
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Identification of a novel selective inhibitor of mutant isocitrate dehydrogenase 1 at allosteric site by docking-based virtual screeningElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra21617j
Zou, Fangxia, Pusch, Stefan, Eisel, Jessica, Ma, Tianfang, Zhu, Qihua, Deng, Dawei, Gu, Yueqing, Xu, Yungen, von Deimling, Andreas, Zha, Xiaoming
Year of Publication 11.10.2016
Year of Publication 11.10.2016
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