New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds
Katalinić, Maja, Zandona, Antonio, Ramić, Alma, Zorbaz, Tamara, Primožič, Ines, Kovarik, Zrinka
Published in Molecules (Basel, Switzerland) (22.07.2017)
Published in Molecules (Basel, Switzerland) (22.07.2017)
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Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease
Gok, Muslum, Madrer, Nimrod, Zorbaz, Tamara, Bennett, Estelle R, Greenberg, David, Bennett, David A, Soreq, Hermona
Published in Frontiers in molecular neuroscience (02.09.2022)
Published in Frontiers in molecular neuroscience (02.09.2022)
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Journal Article
Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Shulman, Dana, Dubnov, Serafima, Zorbaz, Tamara, Madrer, Nimrod, Paldor, Iddo, Bennett, David A, Seshadri, Sudha, Mufson, Elliott J, Greenberg, David S, Loewenstein, Yonatan, Soreq, Hermona
Published in Alzheimer's & dementia (01.11.2023)
Published in Alzheimer's & dementia (01.11.2023)
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Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents
Zorbaz, Tamara, Malinak, David, Maraković, Nikola, Maček Hrvat, Nikolina, Zandona, Antonio, Novotny, Michal, Skarka, Adam, Andrys, Rudolf, Benkova, Marketa, Soukup, Ondrej, Katalinić, Maja, Kuca, Kamil, Kovarik, Zrinka, Musilek, Kamil
Published in Journal of medicinal chemistry (13.12.2018)
Published in Journal of medicinal chemistry (13.12.2018)
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Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
Zorbaz, Tamara, Malinak, David, Hofmanova, Tereza, Maraković, Nikola, Žunec, Suzana, Hrvat, Nikolina Maček, Andrys, Rudolf, Psotka, Miroslav, Zandona, Antonio, Svobodova, Jana, Prchal, Lukas, Fingler, Sanja, Katalinić, Maja, Kovarik, Zrinka, Musilek, Kamil
Published in European journal of medicinal chemistry (05.08.2022)
Published in European journal of medicinal chemistry (05.08.2022)
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High‐throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory‐deprived cortical cholinergic VIP/CHAT neurons
Yayon, Nadav, Amsalem, Oren, Zorbaz, Tamara, Yakov, Or, Dubnov, Serafima, Winek, Katarzyna, Dudai, Amir, Adam, Gil, Schmidtner, Anna K, Tessier‐Lavigne, Marc, Renier, Nicolas, Habib, Naomi, Segev, Idan, London, Michael, Soreq, Hermona
Published in The EMBO journal (04.01.2023)
Published in The EMBO journal (04.01.2023)
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Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration
Zorbaz, Tamara, Braïki, Anissa, Maraković, Nikola, Renou, Julien, de la Mora, Eugenio, Maček Hrvat, Nikolina, Katalinić, Maja, Silman, Israel, Sussman, Joel L., Mercey, Guillaume, Gomez, Catherine, Mougeot, Romain, Pérez, Belén, Baati, Rachid, Nachon, Florian, Weik, Martin, Jean, Ludovic, Kovarik, Zrinka, Renard, Pierre‐Yves
Published in Chemistry : a European journal (05.07.2018)
Published in Chemistry : a European journal (05.07.2018)
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Journal Article
Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase
Kovarik, Zrinka, Kalisiak, Jarosław, Hrvat, Nikolina Maček, Katalinić, Maja, Zorbaz, Tamara, Žunec, Suzana, Green, Carol, Radić, Zoran, Fokin, Valery V., Sharpless, K. Barry, Taylor, Palmer
Published in Chemistry : a European journal (15.03.2019)
Published in Chemistry : a European journal (15.03.2019)
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Journal Article
Stoichiometry of the Heteromeric Nicotinic Receptors of the Renshaw Cell
Lamotte d'Incamps, Boris, Zorbaz, Tamara, Dingova, Dominika, Krejci, Eric, Ascher, Philippe
Published in The Journal of neuroscience (23.05.2018)
Published in The Journal of neuroscience (23.05.2018)
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Journal Article
Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning
Zorbaz, Tamara, Mišetić, Petra, Probst, Nicolas, Žunec, Suzana, Zandona, Antonio, Mendaš, Gordana, Micek, Vedran, Maček Hrvat, Nikolina, Katalinić, Maja, Braïki, Anissa, Jean, Ludovic, Renard, Pierre-Yves, Gabelica Marković, Vesna, Kovarik, Zrinka
Published in ACS chemical neuroscience (01.04.2020)
Published in ACS chemical neuroscience (01.04.2020)
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Journal Article
Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase
Kovarik, Zrinka, Maček Hrvat, Nikolina, Kalisiak, Jarosław, Katalinić, Maja, Sit, Rakesh K., Zorbaz, Tamara, Radić, Zoran, Fokin, Valery V., Sharpless, K. Barry, Taylor, Palmer
Published in Toxicology and applied pharmacology (01.06.2019)
Published in Toxicology and applied pharmacology (01.06.2019)
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Journal Article
Potent lipophilic 3-hydroxy-2-pyridinium aldoxime reactivators of phosphorylated cholinesterases
Zorbaz, Tamara, Renard, Pierre-Yves, Kovarik, Zrinka, Mišetić, Petra, Maraković, Nikola, Zandona, Antonio, Katalinić, Maja, Hrvat, Nikolina Maček, Braiki, Anissa, Marković, Vesna Gabelica, Jean, Ludovic
Published in Arhiv za higijenu rada i toksikologiju (01.07.2018)
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Published in Arhiv za higijenu rada i toksikologiju (01.07.2018)
Journal Article
Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Shulman, Dana, Dubnov, Serafima, Zorbaz, Tamara, Madrer, Nimrod, Paldor, Iddo, Bennett, David A, Seshadri, Sudha, Mufson, Elliott J, Greenberg, David S, Loewenstein, Yonatan, Soreq, Hermona
Published in bioRxiv : the preprint server for biology (20.02.2023)
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Published in bioRxiv : the preprint server for biology (20.02.2023)
Journal Article
Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Shulman, Dana, Dubnov, Serafima, Zorbaz, Tamara, Madrer, Nimrod, Paldor, Iddo, Bennett, David A, Seshadri, Sudha, Mufson, Elliott J, Greenberg, David, Loewenstein, Yonatan, Soreq, Hermona Samuel
Published in bioRxiv (20.02.2023)
Published in bioRxiv (20.02.2023)
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