Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
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Published in Nature communications (15.10.2024)
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Published in Nature structural & molecular biology (01.08.2012)
Published in Nature structural & molecular biology (01.08.2012)
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The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides
Houssen, Wael E., Koehnke, Jesko, Zollman, David, Vendome, Jeremie, Raab, Andrea, Smith, Margaret C. M., Naismith, James H., Jaspars, Marcel
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Published in Chembiochem : a European journal of chemical biology (21.12.2012)
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BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
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Published in Nature chemical biology (01.07.2019)
Published in Nature chemical biology (01.07.2019)
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Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers
Brem, Jürgen, van Berkel, Sander S, Zollman, David, Lee, Sook Y, Gileadi, Opher, McHugh, Peter J, Walsh, Timothy R, McDonough, Michael A, Schofield, Christopher J
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Published in Antimicrobial agents and chemotherapy (01.01.2016)
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In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors
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Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Targeting cancer with small-molecule pan-KRAS degraders
Popow, Johannes, Farnaby, William, Gollner, Andreas, Kofink, Christiane, Fischer, Gerhard, Wurm, Melanie, Zollman, David, Wijaya, Andre, Mischerikow, Nikolai, Hasenoehrl, Carina, Prokofeva, Polina, Arnhof, Heribert, Arce-Solano, Silvia, Bell, Sammy, Boeck, Georg, Diers, Emelyne, Frost, Aileen B, Goodwin-Tindall, Jake, Karolyi-Oezguer, Jale, Khan, Shakil, Klawatsch, Theresa, Koegl, Manfred, Kousek, Roland, Kratochvil, Barbara, Kropatsch, Katrin, Lauber, Arnel A, McLennan, Ross, Olt, Sabine, Peter, Daniel, Petermann, Oliver, Roessler, Vanessa, Stolt-Bergner, Peggy, Strack, Patrick, Strauss, Eva, Trainor, Nicole, Vetma, Vesna, Whitworth, Claire, Zhong, Siying, Quant, Jens, Weinstabl, Harald, Kuster, Bernhard, Ettmayer, Peter, Ciulli, Alessio
Published in Science (American Association for the Advancement of Science) (20.09.2024)
Published in Science (American Association for the Advancement of Science) (20.09.2024)
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The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase That Operates with a Defined Order of Reaction
Koehnke, Jesko, Bent, Andrew F., Zollman, David, Smith, Kieran, Houssen, Wael E., Zhu, Xiaofeng, Mann, Greg, Lebl, Tomas, Scharff, Richard, Shirran, Sally, Botting, Catherine H., Jaspars, Marcel, Schwarz-Linek, Ulrich, Naismith, James H.
Published in Angewandte Chemie International Edition (23.12.2013)
Published in Angewandte Chemie International Edition (23.12.2013)
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Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
Farnaby, William, Koegl, Manfred, Roy, Michael J., Whitworth, Claire, Diers, Emelyne, Trainor, Nicole, Zollman, David, Steurer, Steffen, Karolyi-Oezguer, Jale, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Galant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Gerstberger, Thomas, Schnitzer, Renate, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Ehrenhöfer-Wölfer, Katharina, Wöhrle, Simon, Boehmelt, Guido, Rinnenthal, Joerg, Arnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio
Published in Nature chemical biology (01.08.2019)
Published in Nature chemical biology (01.08.2019)
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Journal Article
Cover Picture: The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides (ChemBioChem 18/2012)
Houssen, Wael E., Koehnke, Jesko, Zollman, David, Vendome, Jeremie, Raab, Andrea, Smith, Margaret C. M., Naismith, James H., Jaspars, Marcel
Published in Chembiochem : a European journal of chemical biology (21.12.2012)
Published in Chembiochem : a European journal of chemical biology (21.12.2012)
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Journal Article
The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase That Operates with a Defined Order of Reaction
Koehnke, Jesko, Bent, Andrew F., Zollman, David, Smith, Kieran, Houssen, Wael E., Zhu, Xiaofeng, Mann, Greg, Lebl, Tomas, Scharff, Richard, Shirran, Sally, Botting, Catherine H., Jaspars, Marcel, Schwarz-Linek, Ulrich, Naismith, James H.
Published in Angewandte Chemie (23.12.2013)
Published in Angewandte Chemie (23.12.2013)
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Journal Article
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
Kroupova, Alena, Spiteri, Valentina A, Furihata, Hirotake, Darren, Darren, Ramachandran, Sarath, Rutter, Zoe, Chakraborti, Sohini, Haubrich, Kevin, Pethe, Julie, Gonzales, Denzel, Wijaya, Andre, Rodriguez-Rios, Maria, Lynch, Dylan M, Farnaby, William, Nakasone, Mark, Zollman, David, Ciulli, Alessio
Published in bioRxiv (20.01.2024)
Published in bioRxiv (20.01.2024)
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Paper
KRAS DEGRADING COMPOUNDS COMPRISING ANNULATED 2-AMINO-3-CYANO THIOPHENES
Broeker, Joachim, McLennan, Ross, Weinstabl, Harald, Gollner, Andreas, Zhong, Siying, Waterson, Alex, Hodges, Tim, Smethurst, Christian Alan Paul, Zollman, David, Diers, Emelyne, Cui, Jianwen, Schmiedel, Martin, Little, Andrew, Mantoulidis, Andreas, Abbott, Jason, Kofink, Christiane, Ciulli, Aleissio, Sarkar, Dhruba, Fesik, Stephen W, Trainor, Nicole, Goodwin-Tindall, Jake, Farnaby, William, Popow, Johannes
Year of Publication 09.10.2024
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Year of Publication 09.10.2024
Patent
KRAS DEGRADING COMPOUNDS COMPRISING ANNULATED 2-AMINO-3-CYANO THIOPHENES
FARNABY, William, MANTOULIDIS, Andreas, SARKAR, Dhruba, TRAINOR, Nicole, LITTLE, Andrew, BROEKER, Joachim, KOFINK, Christiane, WEINSTABL, Harald, SMETHURST, Christian Alan Paul, SCHMIEDEL, Martin, CUI, Jianwen, DIERS, Emelyne, ZHONG, Siying, WATERSON, Alex, MCLENNAN, Ross, CIULLI, Alessio, ZOLLMAN, David, FESIK, Stephen W, GOODWIN-TINDALL, Jake, ABBOTT, Jason, GOLLNER, Andreas, POPOW, Johannes
Year of Publication 08.06.2023
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Year of Publication 08.06.2023
Patent
The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase That Operates with a Defined Order of Reaction
Koehnke, Jesko, Bent, Andrew F., Zollman, David, Smith, Kieran, Houssen, Wael E., Zhu, Xiaofeng, Mann, Greg, Lebl, Tomas, Scharff, Richard, Shirran, Sally, Botting, Catherine H., Jaspars, Marcel, Schwarz‐Linek, Ulrich, Naismith, James H.
Published in Angewandte Chemie (23.12.2013)
Published in Angewandte Chemie (23.12.2013)
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Journal Article