PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells
Maginn, E N, Browne, P V, Hayden, P, Vandenberghe, E, MacDonagh, B, Evans, P, Goodyer, M, Tewari, P, Campiani, G, Butini, S, Williams, D C, Zisterer, D M, Lawler, M P, McElligott, A M
Published in British journal of cancer (18.01.2011)
Published in British journal of cancer (18.01.2011)
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Journal Article
Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo
Bright, S A, McElligott, A M, O'Connell, J W, O'Connor, L, Carroll, P, Campiani, G, Deininger, M W, Conneally, E, Lawler, M, Williams, D C, Zisterer, D M
Published in British journal of cancer (11.05.2010)
Published in British journal of cancer (11.05.2010)
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Journal Article
Pre-clinical evaluation of a novel class of anti-cancer agents, the Pyrrolo-1, 5-benzoxazepines
Greene, L M, Butini, S, Campiani, G, Williams, D C, Zisterer, D M
Published in Journal of Cancer (01.01.2016)
Published in Journal of Cancer (01.01.2016)
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Journal Article
In vitro cytotoxicity of a composite resin and compomer
Quinlan, C. A., Zisterer, D. M., Tipton, K. F., O'Sullivan, M. I.
Published in International endodontic journal (01.01.2002)
Published in International endodontic journal (01.01.2002)
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Journal Article
Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands
Campiani, Giuseppe, Nacci, Vito, Fiorini, Isabella, De Filippis, Maria P, Garofalo, Antonio, Ciani, Silvia M, Greco, Giovanni, Novellino, Ettore, Williams, D. Clive, Zisterer, Daniela M, Woods, Margaret J, Mihai, Camelia, Manzoni, Cristina, Mennini, Tiziana
Published in Journal of medicinal chemistry (30.08.1996)
Published in Journal of medicinal chemistry (30.08.1996)
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Journal Article
Antiproliferative action of pyrrolobenzoxazepine derivatives in cultured cells: Absence of correlation with binding to the peripheral-type benzodiazepine binding site
Zisterer, Daniela M, Hance, Nicole, Campiani, Giuseppe, Garofalo, Antonio, Nacci, Vito, Williams, D.Clive
Published in Biochemical pharmacology (15.02.1998)
Published in Biochemical pharmacology (15.02.1998)
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Journal Article
Calmidazolium and other imidazole compounds affect steroidogenesis in Y1 cells: Lack of involvement of the peripheral-type benzodiazepine receptor
Zisterer, Daniela M., Williams, D.Clive
Published in The Journal of steroid biochemistry and molecular biology (01.02.1997)
Published in The Journal of steroid biochemistry and molecular biology (01.02.1997)
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Journal Article
Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6
Mc Gee, Margaret M, Hyland, Edel, Campiani, Giuseppe, Ramunno, Anna, Nacci, Vito, Zisterer, Daniela M
Published in FEBS letters (27.03.2002)
Published in FEBS letters (27.03.2002)
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Journal Article
Caspase-activated DNase (CAD)-independent oligonucleosomal DNA fragmentation in chronic myeloid leukaemia cells; a requirement for serine protease and Mn2+-dependent acidic endonuclease activity
McGrath, L B, Onnis, V, Campiani, G, Williams, D C, Zisterer, D M, Mc Gee, M M
Published in Apoptosis (London) (01.09.2006)
Published in Apoptosis (London) (01.09.2006)
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Journal Article
Benzoxepin-Derived Estrogen Receptor Modulators: A Novel Molecular Scaffold for the Estrogen Receptor
Lloyd, David G, Hughes, Rosario B, Zisterer, Daniela M, Williams, D. Clive, Fattorusso, Caterina, Catalanotti, Bruno, Campiani, Giuseppe, Meegan, Mary J
Published in Journal of medicinal chemistry (04.11.2004)
Published in Journal of medicinal chemistry (04.11.2004)
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Journal Article
Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line
Meegan, M J, Hughes, R B, Lloyd, D G, Williams, D C, Zisterer, D M
Published in Anti-cancer drug design (01.02.2001)
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Published in Anti-cancer drug design (01.02.2001)
Journal Article
Activation of the c-Jun N-terminal Kinase (JNK) Signaling Pathway Is Essential during PBOX-6-induced Apoptosis in Chronic Myelogenous Leukemia (CML) Cells
Mc Gee, Margaret M., Campiani, Giuseppe, Ramunno, Anna, Nacci, Vito, Lawler, Mark, Williams, D. Clive, Zisterer, Daniela M.
Published in The Journal of biological chemistry (24.05.2002)
Published in The Journal of biological chemistry (24.05.2002)
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Journal Article
The effects of the peripheral-type benzodiazepine acceptor ligands, Ro 5-4864 and PK 11195, on mitochondrial respiration
Zisterer, D M, Gorman, A M, Williams, D C, Murphy, M P
Published in Methods and findings in experimental and clinical pharmacology (01.03.1992)
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Published in Methods and findings in experimental and clinical pharmacology (01.03.1992)
Journal Article
Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents
Zisterer, D M, McGee, M M, Campiani, G, Ramunno, A, Fattorusso, C, Nacci, V, Lawler, M, Williams, D C
Published in Biochemical Society transactions (01.11.2001)
Published in Biochemical Society transactions (01.11.2001)
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Journal Article
Pyrrolo-1,5-benzoxazepines Induce Apoptosis in Chronic Myelogenous Leukemia (CML) Cells by Bypassing the Apoptotic Suppressor Bcr-Abl
Mc Gee, M M, Campiani, G, Ramunno, A, Fattorusso, C, Nacci, V, Lawler, M, Williams, D C, Zisterer, D M
Published in The Journal of pharmacology and experimental therapeutics (01.01.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.2001)
Journal Article
Two cellular and subcellular locations for the peripheral-type benzodiazepine receptor in rat liver
Woods, Margaret J., Zisterer, Daniela M., Williams, D.Clive
Published in Biochemical pharmacology (17.05.1996)
Published in Biochemical pharmacology (17.05.1996)
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