Cisplatin Nephrotoxicity Is Critically Mediated via the Human Organic Cation Transporter 2
Ciarimboli, Giuliano, Ludwig, Thomas, Lang, Detlef, Pavenstädt, Hermann, Koepsell, Hermann, Piechota, Hans-Jürgen, Haier, Jörg, Jaehde, Ulrich, Zisowsky, Jochen, Schlatter, Eberhard
Published in The American journal of pathology (01.12.2005)
Published in The American journal of pathology (01.12.2005)
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Drug Development for Pediatric Populations: Regulatory Aspects
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Book Review
The Raf kinase inhibitor BAY 43-9006 reduces cellular uptake of platinum compounds and cytotoxicity in human colorectal carcinoma cell lines
Heim, Martina, Scharifi, Mariam, Zisowsky, Jochen, Jaehde, Ulrich, Voliotis, Dimitris, Seeber, Siegfried, Strumberg, Dirk
Published in Anti-cancer drugs (01.02.2005)
Published in Anti-cancer drugs (01.02.2005)
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Population pharmacokinetics of regorafenib in solid tumours: Exposure in clinical practice considering enterohepatic circulation and food intake
Keunecke, Anne, Hoefman, Sven, Drenth, Henk‐Jan, Zisowsky, Jochen, Cleton, Adriaan, Ploeger, Bart A.
Published in British journal of clinical pharmacology (01.12.2020)
Published in British journal of clinical pharmacology (01.12.2020)
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Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells
Zisowsky, Jochen, Koegel, Susanne, Leyers, Stefan, Devarakonda, Krishna, Kassack, Matthias U., Osmak, Maja, Jaehde, Ulrich
Published in Biochemical pharmacology (15.01.2007)
Published in Biochemical pharmacology (15.01.2007)
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Challenges in collecting pharmacokinetic and pharmacodynamic information in an intensive care setting: PK/PD modelling of clazosentan in patients with aneurysmal subarachnoid haemorrhage
Zisowsky, Jochen, Fuseau, Eliane, Bruderer, Shirin, Krause, Andreas, Dingemanse, Jasper
Published in European journal of clinical pharmacology (01.04.2014)
Published in European journal of clinical pharmacology (01.04.2014)
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Pharmacokinetic/Pharmacodynamic Modelling of Receptor Internalization with CRTH2 Antagonists to Optimize Dose Selection
Krause, Andreas, Zisowsky, Jochen, Strasser, Daniel S., Gehin, Martine, Sidharta, Patricia N., Groenen, Peter M. A., Dingemanse, Jasper
Published in Clinical pharmacokinetics (01.07.2016)
Published in Clinical pharmacokinetics (01.07.2016)
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Pediatric Development of Bosentan Facilitated by Modeling and Simulation
Zisowsky, Jochen, Géhin, Martine, Kusic-Pajic, Andjela, Krause, Andreas, Beghetti, Maurice, Dingemanse, Jasper
Published in Paediatric drugs (01.04.2017)
Published in Paediatric drugs (01.04.2017)
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Long‐term activation of SAPK/JNK, p38 kinase and fas‐L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance
Brozovic, Anamaria, Fritz, Gerhard, Christmann, Markus, Zisowsky, Jochen, Jaehde, Ulrich, Osmak, Maja, Kaina, Bernd
Published in International journal of cancer (20.12.2004)
Published in International journal of cancer (20.12.2004)
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A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects
Géhin, Martine, Strasser, Daniel S, Zisowsky, Jochen, Farine, Hervé, Groenen, Peter M A, Dingemanse, Jasper, Sidharta, Patricia N
Published in Journal of clinical pharmacology (01.07.2015)
Published in Journal of clinical pharmacology (01.07.2015)
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