Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins
Dorayappan, Kalpana Deepa Priya, Wanner, Ross, Wallbillich, John J., Saini, Uksha, Zingarelli, Roman, Suarez, Adrian A., Cohn, David E., Selvendiran, Karuppaiyah
Published in Oncogene (01.07.2018)
Published in Oncogene (01.07.2018)
Get full text
Journal Article
A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer
Dorayappan, Kalpana Deepa Priya, Gardner, Miranda L, Hisey, Colin L, Zingarelli, Roman A, Smith, Brentley Q, Lightfoot, Michelle D S, Gogna, Rajan, Flannery, Meghan M, Hays, John, Hansford, Derek J, Freitas, Michael A, Yu, Lianbo, Cohn, David E, Selvendiran, Karuppaiyah
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
High Glucose-Mediated STAT3 Activation in Endometrial Cancer Is Inhibited by Metformin: Therapeutic Implications for Endometrial Cancer
Wallbillich, John J, Josyula, Srirama, Saini, Uksha, Zingarelli, Roman A, Dorayappan, Kalpana Deepa Priya, Riley, Maria K, Wanner, Ross A, Cohn, David E, Selvendiran, Karuppaiyah
Published in PloS one (23.01.2017)
Published in PloS one (23.01.2017)
Get full text
Journal Article
MAX Mutations in Endometrial Cancer: Clinicopathologic Associations and Recurrent MAX p.His28Arg Functional Characterization
Walker, Christopher J, Rush, Craig M, Dama, Paola, O'Hern, Matthew J, Cosgrove, Casey M, Gillespie, Jessica L, Zingarelli, Roman A, Smith, Blair, Stein, Maggie E, Mutch, David G, Shakya, Reena, Chang, Chia-Wen, Selvendiran, Karuppaiyah, Song, Jonathan W, Cohn, David E, Goodfellow, Paul J
Published in JNCI : Journal of the National Cancer Institute (01.05.2018)
Published in JNCI : Journal of the National Cancer Institute (01.05.2018)
Get full text
Journal Article
Obesity-induced extracellular vesicles proteins drive the endometrial cancer pathogenesis: therapeutic potential of HO-3867 and Metformin
Sakaue, Takahiko, Dorayappan, Kalpana Deepa Priya, Zingarelli, Roman, Khadraoui, Wafa, Anbalagan, Muralidharan, Wallbillich, John, Bognar, Balazs, Wanner, Ross, Cosgrove, Casey, Suarez, Adrian, Koga, Hironori, Maxwell, G Larry, O'Malley, David M, Cohn, David E, Selvendiran, Karuppaiyah
Published in Oncogene (16.10.2024)
Published in Oncogene (16.10.2024)
Get full text
Journal Article
Abstract 5798: Exosomal oncogenic proteins promote tumor progression, metastasis and chemoresistance in ovarian cancer
Dorayappan, Kalpana Deepa Priya, Wanner, Ross A., Zingarelli, Roman A., Saini, Uksha, Karuppaiyah, Selvendiran, Cohn, David E.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract 5888: Tmem 205-mediated cisplatin resistance in ovarian clear cell carcinoma (OCCC) is overcome by herpes simplex virus (oHSV)/cisplatin combination therapy
Saini, Uksha, Riley, Maria, Dorayappan, Kalpana Deepa, Bolyard, Chelsea, Kaur, Balveen, Zingarelli, Roman, Konishi, Ikuo, Kuppusamy, Periannan, Maxwell, George Larry, Cohn, David E., Selvendiran, Karuppaiyah
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract 3377: Exploring the role of obesity-induced exosome secretion and associated proteins in endometrial cancer pathogenesis: A roadmap for prevention through exosome inhibition
Sakaue, Takahiko, Dorayappan, Kalpana Deepa Priya, Zingarelli, Roman, Khadraoui, Wafa, Anbalagan, Muralidharan, Wallbillich, John, Wascovich, Mark, Paramita, Pragyan, Suarez, Adrian, Cosgrove, Casey, Maxwell, Larry G., Koga, Hironori, O’Malley, David, Cohn, David, Karuppaiyah, Selvendiran
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 4236: Obesity-associated endometrial cancer: Identifying the contributions of TMEM205 expression to the pathogenesis of disease
Sakaue, Takahiko, Zingarelli, Roman, Khadraoui, Wafa, Saini, Uksha, Wallbillich, John, Anbazhakan, Muralidharan, Warner, Ross, Dorayappan, Kalpana Deepa Priya, Kalaiyarasan, Deepika, Morton, Molly, Cosgrove, Casey, Suarez, Adrian, Maxwell, Larry J., O'Malley, David, Cohn, David E., Selvendiran, Karuppaiyah
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article