Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans
Brunt, Vienna E, Gioscia-Ryan, Rachel A, Casso, Abigail G, VanDongen, Nicholas S, Ziemba, Brian P, Sapinsley, Zachary J, Richey, James J, Zigler, Melanie C, Neilson, Andrew P, Davy, Kevin P, Seals, Douglas R
Published in Hypertension (Dallas, Tex. 1979) (01.07.2020)
Published in Hypertension (Dallas, Tex. 1979) (01.07.2020)
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Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway
Ziemba, Brian P., Burke, John E., Masson, Glenn, Williams, Roger L., Falke, Joseph J.
Published in Biophysical journal (26.04.2016)
Published in Biophysical journal (26.04.2016)
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Time-Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above-Normal Blood Pressure
Craighead, Daniel H, Heinbockel, Thomas C, Freeberg, Kaitlin A, Rossman, Matthew J, Jackman, Rachel A, Jankowski, Lindsey R, Hamilton, Makinzie N, Ziemba, Brian P, Reisz, Julie A, D'Alessandro, Angelo, Brewster, L Madden, DeSouza, Christopher A, You, Zhiying, Chonchol, Michel, Bailey, E Fiona, Seals, Douglas R
Published in Journal of the American Heart Association (06.07.2021)
Published in Journal of the American Heart Association (06.07.2021)
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Doxorubicin-Induced Oxidative Stress and Endothelial Dysfunction in Conduit Arteries Is Prevented by Mitochondrial-Specific Antioxidant Treatment
Clayton, Zachary S., Brunt, Vienna E., Hutton, David A., VanDongen, Nicholas S., D’Alessandro, Angelo, Reisz, Julie A., Ziemba, Brian P., Seals, Douglas R.
Published in JACC CardioOncology (01.09.2020)
Published in JACC CardioOncology (01.09.2020)
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Assembly of Membrane-Bound Protein Complexes: Detection and Analysis by Single Molecule Diffusion
Ziemba, Brian P, Knight, Jefferson D, Falke, Joseph J
Published in Biochemistry (Easton) (28.02.2012)
Published in Biochemistry (Easton) (28.02.2012)
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Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging
Clayton, Zachary S., Hutton, David A., Brunt, Vienna E., VanDongen, Nicholas S., Ziemba, Brian P., Casso, Abigail G., Greenberg, Nathan T., Mercer, Amanda N., Rossman, Matthew J., Campisi, Judith, Melov, Simon, Seals, Douglas R.
Published in American journal of physiology. Heart and circulatory physiology (01.07.2021)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2021)
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Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin
Clayton, Zachary S, Brunt, Vienna E, Hutton, David A, Casso, Abigail G, Ziemba, Brian P, Melov, Simon, Campisi, Judith, Seals, Douglas R
Published in Hypertension (Dallas, Tex. 1979) (01.05.2021)
Published in Hypertension (Dallas, Tex. 1979) (01.05.2021)
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Journal Article
Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans
Brunt, Vienna E, Casso, Abigail G, Gioscia-Ryan, Rachel A, Sapinsley, Zachary J, Ziemba, Brian P, Clayton, Zachary S, Bazzoni, Amy E, VanDongen, Nicholas S, Richey, James J, Hutton, David A, Zigler, Melanie C, Neilson, Andrew P, Davy, Kevin P, Seals, Douglas R
Published in Hypertension (Dallas, Tex. 1979) (01.08.2021)
Published in Hypertension (Dallas, Tex. 1979) (01.08.2021)
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Lifelong voluntary aerobic exercise prevents age‐ and Western diet‐ induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice
Gioscia‐Ryan, Rachel A., Clayton, Zachary S., Zigler, Melanie C., Richey, James J., Cuevas, Lauren M., Rossman, Matthew J., Battson, Micah L., Ziemba, Brian P., Hutton, David A., VanDongen, Nicholas S., Seals, Douglas R.
Published in The Journal of physiology (01.02.2021)
Published in The Journal of physiology (01.02.2021)
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Initiation of 3,3‐dimethyl‐1‐butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice
Casso, Abigail G., VanDongen, Nicholas S., Gioscia‐Ryan, Rachel A., Clayton, Zachary S., Greenberg, Nathan T., Ziemba, Brian P., Hutton, David A., Neilson, Andrew P., Davy, Kevin P., Seals, Douglas R., Brunt, Vienna E.
Published in The Journal of physiology (01.11.2022)
Published in The Journal of physiology (01.11.2022)
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Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults
Martens, Christopher R., Rossman, Matthew J., Mazzo, Melissa R., Jankowski, Lindsey R., Nagy, Erzsebet E., Denman, Blair A., Richey, James J., Johnson, Sarah A., Ziemba, Brian P., Wang, Yang, Peterson, Courtney M., Chonchol, Michel, Seals, Douglas R.
Published in GeroScience (01.04.2020)
Published in GeroScience (01.04.2020)
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