Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance
Classen, Sandra, Rahlf, Elena, Jungwirth, Johannes, Albers, Nina, Hebestreit, Luca Philipp, Zielinski, Alexandra, Poole, Lena, Groth, Marco, Koch, Philipp, Liehr, Thomas, Kankel, Stefanie, Cordes, Nils, Petersen, Cordula, Rothkamm, Kai, Pospiech, Helmut, Borgmann, Kerstin
Published in International journal of molecular sciences (01.11.2022)
Published in International journal of molecular sciences (01.11.2022)
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Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins
Dyshlovoy, Sergey A., Mansour, Wael Y., Ramm, Natalia A., Hauschild, Jessica, Zhidkov, Maxim E., Kriegs, Malte, Zielinski, Alexandra, Hoffer, Konstantin, Busenbender, Tobias, Glumakova, Ksenia A., Spirin, Pavel V., Prassolov, Vladimir S., Tilki, Derya, Graefen, Markus, Bokemeyer, Carsten, von Amsberg, Gunhild
Published in Scientific reports (23.05.2024)
Published in Scientific reports (23.05.2024)
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Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
von Amsberg, Gunhild, Zilles, Mirjam, Mansour, Wael, Gild, Philipp, Alsdorf, Winfried, Kaune, Moritz, Böckelmann, Lukas, Hauschild, Jessica, Krisp, Christoph, Rohlfing, Tina, Saygi, Ceren, Alawi, Malik, Zielinski, Alexandra, Langebrake, Claudia, Oh-Hohenhorst, Su Jung, Perner, Sven, Tilki, Derya, Schlüter, Hartmut, Graefen, Markus, Dyshlovoy, Sergey A, Bokemeyer, Carsten
Published in International journal of molecular sciences (29.11.2022)
Published in International journal of molecular sciences (29.11.2022)
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1779: Genomic instability due to chromatin deregulation in SPOP-deficient prostate cancer cells
Fahmy, Shaimaa, Voß, Hannah, Zielinski, Alexandra, Eckhardt, Alicia, Struve, Nina, Oing, Christoph, Schlüter, Hartmut, Schüller, Ulrich, Petersen, Cordula, Rothkamm, Kai, Mansour, Wael Y.
Published in Radiotherapy and oncology (01.05.2024)
Published in Radiotherapy and oncology (01.05.2024)
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Abstract 3364: RAI2 maintains genome stability of breast cancer cells
Boettcher, Lena, Zobiak, Bernd, Borgmann, Kerstin, Zielinski, Alexandra, Failla, Antonio Virgilio, Pantel, Klaus, Wikman, Harriet, Werner, Stefan
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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The POLD1R689W variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors
Job, Albert, Tatura, Marina, Schäfer, Cora, Lutz, Veronika, Schneider, Hanna, Lankat-Buttgereit, Brigitte, Zielinski, Alexandra, Borgmann, Kerstin, Bauer, Christian, Gress, Thomas M., Buchholz, Malte, Gallmeier, Eike
Published in Scientific reports (03.11.2020)
Published in Scientific reports (03.11.2020)
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Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization Against PARP1 Inhibition in a Replication-Dependent Manner
Rieckhoff, Johanna, Meyer, Felix, Classen, Sandra, Zielinski, Alexandra, Riepen, Britta, Wikman, Harriet, Petersen, Cordula, Rothkamm, Kai, Borgmann, Kerstin, Parplys, Ann Christin
Published in Cancers (01.10.2020)
Published in Cancers (01.10.2020)
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DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients
Bold, Ioan T, Specht, Ann-Kathrin, Droste, Conrad F, Zielinski, Alexandra, Meyer, Felix, Clauditz, Till S, Münscher, Adrian, Werner, Stefan, Rothkamm, Kai, Petersen, Cordula, Borgmann, Kerstin
Published in Cancers (10.03.2021)
Published in Cancers (10.03.2021)
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PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response
Wurster, Stephanie, Hennes, Fabian, Parplys, Ann C, Seelbach, Jasna I, Mansour, Wael Y, Zielinski, Alexandra, Petersen, Cordula, Clauditz, Till S, Münscher, Adrian, Friedl, Anna A, Borgmann, Kerstin
Published in Oncotarget (01.03.2016)
Published in Oncotarget (01.03.2016)
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S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci
Foertsch, Franziska, Szambowska, Anna, Weise, Anja, Zielinski, Alexandra, Schlott, Bernhard, Kraft, Florian, Mrasek, Kristin, Borgmann, Kerstin, Pospiech, Helmut, Grosse, Frank, Melle, Christian
Published in Cell cycle (Georgetown, Tex.) (17.10.2016)
Published in Cell cycle (Georgetown, Tex.) (17.10.2016)
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Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair
Elsesy, Mohamed E., Oh-Hohenhorst, Su Jung, Löser, Anastassia, Oing, Christoph, Mutiara, Sally, Köcher, Sabrina, Meien, Stefanie, Zielinski, Alexandra, Burdak-Rothkamm, Susanne, Tilki, Derya, Huland, Hartwig, Schwarz, Rudolf, Petersen, Cordula, Bokemeyer, Carsten, Rothkamm, Kai, Mansour, Wael Y.
Published in Cancers (01.09.2020)
Published in Cancers (01.09.2020)
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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress
Pai, Govind M, Zielinski, Alexandra, Koalick, Dennis, Ludwig, Kristin, Wang, Zhao-Qi, Borgmann, Kerstin, Pospiech, Helmut, Rubio, Ignacio
Published in Oncotarget (20.12.2016)
Published in Oncotarget (20.12.2016)
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The POLD1 R689W variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors
Job, Albert, Tatura, Marina, Schäfer, Cora, Lutz, Veronika, Schneider, Hanna, Lankat-Buttgereit, Brigitte, Zielinski, Alexandra, Borgmann, Kerstin, Bauer, Christian, Gress, Thomas M, Buchholz, Malte, Gallmeier, Eike
Published in Scientific reports (03.11.2020)
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Published in Scientific reports (03.11.2020)
Journal Article
S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci
Foertsch, Franziska, Szambowska, Anna, Weise, Anja, Zielinski, Alexandra, Schlott, Bernhard, Kraft, Florian, Mrasek, Kristin, Borgmann, Kerstin, Pospiech, Helmut, Grosse, Frank, Melle, Christian
Published in Cell Cycle (17.10.2016)
Published in Cell Cycle (17.10.2016)
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