Overcoming Depression with 5-HT2A Receptor Ligands
Zięba, Agata, Stępnicki, Piotr, Matosiuk, Dariusz, Kaczor, Agnieszka A.
Published in International journal of molecular sciences (01.01.2022)
Published in International journal of molecular sciences (01.01.2022)
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Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation
Stępnicki, Piotr, Wronikowska-Denysiuk, Olga, Zięba, Agata, Targowska-Duda, Katarzyna M., Bartyzel, Agata, Wróbel, Martyna Z., Wróbel, Tomasz M., Szałaj, Klaudia, Chodkowski, Andrzej, Mirecka, Karolina, Budzyńska, Barbara, Fornal, Emilia, Turło, Jadwiga, Castro, Marián, Kaczor, Agnieszka A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia
Stępnicki, Piotr, Wośko, Sylwia, Bartyzel, Agata, Zięba, Agata, Bartuzi, Damian, Szałaj, Klaudia, Wróbel, Tomasz M., Fornal, Emilia, Carlsson, Jens, Kędzierska, Ewa, Poleszak, Ewa, Castro, Marián, Kaczor, Agnieszka A.
Published in Molecules (Basel, Switzerland) (20.05.2023)
Published in Molecules (Basel, Switzerland) (20.05.2023)
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The Universal 3D QSAR Model for Dopamine D2 Receptor Antagonists
Zięba, Agata, Żuk, Justyna, Bartuzi, Damian, Matosiuk, Dariusz, Poso, Antti, Kaczor, Agnieszka A.
Published in International journal of molecular sciences (14.09.2019)
Published in International journal of molecular sciences (14.09.2019)
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What are the challenges with multi-targeted drug design for complex diseases?
Zięba, Agata, Stępnicki, Piotr, Matosiuk, Dariusz, Kaczor, Agnieszka A
Published in Expert opinion on drug discovery (03.07.2022)
Published in Expert opinion on drug discovery (03.07.2022)
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Caspases in Alzheimer’s Disease: Mechanism of Activation, Role, and Potential Treatment
Wójcik, Piotr, Jastrzębski, Michał K., Zięba, Agata, Matosiuk, Dariusz, Kaczor, Agnieszka A.
Published in Molecular neurobiology (01.07.2024)
Published in Molecular neurobiology (01.07.2024)
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Insufficient antibody validation challenges oestrogen receptor beta research
Andersson, Sandra, Sundberg, Mårten, Pristovsek, Nusa, Ibrahim, Ahmed, Jonsson, Philip, Katona, Borbala, Clausson, Carl-Magnus, Zieba, Agata, Ramström, Margareta, Söderberg, Ola, Williams, Cecilia, Asplund, Anna
Published in Nature communications (15.06.2017)
Published in Nature communications (15.06.2017)
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Discovery and in vitro Evaluation of Novel Serotonin 5‐HT 2A Receptor Ligands Identified Through Virtual Screening
Zięba, Agata, Bartuzi, Damian, Stępnicki, Piotr, Matosiuk, Dariusz, Wróbel, Tomasz M., Laitinen, Tuomo, Castro, Marián, Kaczor, Agnieszka A.
Published in ChemMedChem (15.07.2024)
Published in ChemMedChem (15.07.2024)
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Journal Article
Discovery and in vitro Evaluation of Novel Serotonin 5‐HT2A Receptor Ligands Identified Through Virtual Screening
Zięba, Agata, Bartuzi, Damian, Stępnicki, Piotr, Matosiuk, Dariusz, Wróbel, Tomasz M., Laitinen, Tuomo, Castro, Marián, Kaczor, Agnieszka A.
Published in ChemMedChem (15.07.2024)
Published in ChemMedChem (15.07.2024)
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Journal Article
Development and Characterization of Novel Selective, Non-Basic Dopamine D 2 Receptor Antagonists for the Treatment of Schizophrenia
Stępnicki, Piotr, Wośko, Sylwia, Bartyzel, Agata, Zięba, Agata, Bartuzi, Damian, Szałaj, Klaudia, Wróbel, Tomasz M, Fornal, Emilia, Carlsson, Jens, Kędzierska, Ewa, Poleszak, Ewa, Castro, Marián, Kaczor, Agnieszka A
Published in Molecules (Basel, Switzerland) (20.05.2023)
Published in Molecules (Basel, Switzerland) (20.05.2023)
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Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface
Flowers, Sarah A., Zieba, Agata, Örnros, Jessica, Jin, Chunsheng, Rolfson, Ola, Björkman, Lena I., Eisler, Thomas, Kalamajski, Sebastian, Kamali-Moghaddam, Masood, Karlsson, Niclas G.
Published in Scientific reports (13.10.2017)
Published in Scientific reports (13.10.2017)
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Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization
Dieterich, Lothar C, Mellberg, Sofie, Langenkamp, Elise, Zhang, Lei, Zieba, Agata, Salomäki, Henriikka, Teichert, Martin, Huang, Hua, Edqvist, Per-Henrik, Kraus, Theo, Augustin, Hellmut G, Olofsson, Tommie, Larsson, Erik, Söderberg, Ola, Molema, Grietje, Pontén, Fredrik, Georgii-Hemming, Patrik, Alafuzoff, Irina, Dimberg, Anna
Published in The Journal of pathology (01.11.2012)
Published in The Journal of pathology (01.11.2012)
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Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling
Stępnicki, Piotr, Targowska-Duda, Katarzyna M., Martínez, Antón L., Zięba, Agata, Wronikowska-Denysiuk, Olga, Wróbel, Martyna Z., Bartyzel, Agata, Trzpil, Alicja, Wróbel, Tomasz M., Chodkowski, Andrzej, Mirecka, Karolina, Karcz, Tadeusz, Szczepańska, Katarzyna, Loza, Maria I., Budzyńska, Barbara, Turło, Jadwiga, Handzlik, Jadwiga, Fornal, Emilia, Poleszak, Ewa, Castro, Marián, Kaczor, Agnieszka A.
Published in European journal of medicinal chemistry (05.04.2023)
Published in European journal of medicinal chemistry (05.04.2023)
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Multitarget Derivatives of D2AAK1 as Potential Antipsychotics: The Effect of Substitution in the Indole Moiety
Kondej, Magda, Wróbel, Tomasz M., Targowska‐Duda, Katarzyna M., Leandro Martínez, Antón, Koszła, Oliwia, Stępnicki, Piotr, Zięba, Agata, Paz, Alba, Wronikowska‐Denysiuk, Olga, Loza, Maria I., Castro, Marián, Kaczor, Agnieszka A.
Published in ChemMedChem (03.08.2022)
Published in ChemMedChem (03.08.2022)
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