Endothelial and Smooth Muscle Cell Interaction via FoxM1 Signaling Mediates Vascular Remodeling and Pulmonary Hypertension
Dai, Zhiyu, Zhu, Maggie M, Peng, Yi, Jin, Hua, Machireddy, Narsa, Qian, Zhijian, Zhang, Xianming, Zhao, You-Yang
Published in American journal of respiratory and critical care medicine (15.09.2018)
Published in American journal of respiratory and critical care medicine (15.09.2018)
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Journal Article
Endothelial Autocrine Signaling through CXCL12/CXCR4/FoxM1 Axis Contributes to Severe Pulmonary Arterial Hypertension
Yi, Dan, Liu, Bin, Wang, Ting, Liao, Qi, Zhu, Maggie M, Zhao, You-Yang, Dai, Zhiyu
Published in International journal of molecular sciences (20.03.2021)
Published in International journal of molecular sciences (20.03.2021)
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Journal Article
Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis
Dai, Zhiyu, Cheng, Jianding, Liu, Bin, Yi, Dan, Feng, Anlin, Wang, Ting, An, Lingling, Gao, Chen, Wang, Yibin, Zhu, Maggie M, Zhang, Xianming, Zhao, You-Yang
Published in Journal of the American Heart Association (16.11.2021)
Published in Journal of the American Heart Association (16.11.2021)
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Journal Article
Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α
Dai, Zhiyu, Li, Ming, Wharton, John, Zhu, Maggie M, Zhao, You-Yang
Published in Circulation (New York, N.Y.) (14.06.2016)
Published in Circulation (New York, N.Y.) (14.06.2016)
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Journal Article
Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension
Liu, Bin, Yi, Dan, Pan, Jiakai, Dai, Jingbo, Zhu, Maggie M., Zhao, You‐Yang, Oh, S. Paul, Fallon, Michael B., Dai, Zhiyu
Published in Pulmonary circulation (01.01.2022)
Published in Pulmonary circulation (01.01.2022)
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Journal Article
Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2α Inhibitor
Dai, Zhiyu, Zhu, Maggie M, Peng, Yi, Machireddy, Narsa, Evans, Colin E, Machado, Roberto, Zhang, Xianming, Zhao, You-Yang
Published in American journal of respiratory and critical care medicine (01.12.2018)
Published in American journal of respiratory and critical care medicine (01.12.2018)
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Journal Article
Endothelial PHD2 deficiency induces nitrative stress via suppression of caveolin-1 in pulmonary hypertension
Liu, Bin, Peng, Yi, Yi, Dan, Machireddy, Narsa, Dong, Daoyin, Ramirez, Karina, Dai, Jingbo, Vanderpool, Rebecca, Zhu, Maggie M, Dai, Zhiyu, Zhao, You-Yang
Published in The European respiratory journal (01.12.2022)
Published in The European respiratory journal (01.12.2022)
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Journal Article
GCN2 kinase activation mediates pulmonary vascular remodeling and pulmonary arterial hypertension
Zhu, Maggie M, Dai, Jingbo, Dai, Zhiyu, Peng, Yi, Zhao, You-Yang
Published in JCI insight (24.09.2024)
Published in JCI insight (24.09.2024)
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Journal Article
Abstract 12629: Endothelial Prolyl-4 hydroxylase 2 Deletion Induces Cardiac Hypertrophy and Heart Failure via Hypoxia Inducible Factor-2α Activation
Dai, Zhiyu, Zhu, Maggie M, Gao, Chen, Zhang, Xianming, Zhao, You-Yang
Published in Circulation (New York, N.Y.) (11.11.2016)
Published in Circulation (New York, N.Y.) (11.11.2016)
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Journal Article
PHD2 Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans through HIF-2α
Dai, Zhiyu, Li, Ming, Wharton, John, Zhu, Maggie M., Zhao, You-Yang
Published in Circulation (New York, N.Y.) (25.04.2016)
Published in Circulation (New York, N.Y.) (25.04.2016)
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Journal Article
Abstract 13732: GCN2 Regulates Vascular Remodeling in the Pathogenesis of Pulmonary Arterial Hypertension
Zhu, Maggie M, Dai, Zhiyu, Dai, Jingbo, Peng, Yi, Zhao, Youyang
Published in Circulation (New York, N.Y.) (19.11.2019)
Published in Circulation (New York, N.Y.) (19.11.2019)
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