A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat
Honore, Prisca, Donnelly-Roberts, Diana, Namovic, Marian T, Hsieh, Gin, Zhu, Chang Z, Mikusa, Joe P, Hernandez, Gricelda, Zhong, Chengmin, Gauvin, Donna M, Chandran, Prasant, Harris, Richard, Medrano, Arturo Perez, Carroll, William, Marsh, Kennan, Sullivan, James P, Faltynek, Connie R, Jarvis, Michael F
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
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Journal Article
Indol-3-ylcycloalkyl Ketones: Effects of N1 Substituted Indole Side Chain Variations on CB2 Cannabinoid Receptor Activity
Frost, Jennifer M, Dart, Michael J, Tietje, Karin R, Garrison, Tiffany R, Grayson, George K, Daza, Anthony V, El-Kouhen, Odile F, Yao, Betty B, Hsieh, Gin C, Pai, Madhavi, Zhu, Chang Z, Chandran, Prasant, Meyer, Michael D
Published in Journal of medicinal chemistry (14.01.2010)
Published in Journal of medicinal chemistry (14.01.2010)
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Journal Article
Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats
Hsieh, Gin C, Pai, Madhavi, Chandran, Prasant, Hooker, Bradley A, Zhu, Chang Z, Salyers, Anita K, Wensink, Erica J, Zhan, CenChen, Carroll, William A, Dart, Michael J, Yao, Betty B, Honore, Prisca, Meyer, Michael D
Published in British journal of pharmacology (01.01.2011)
Published in British journal of pharmacology (01.01.2011)
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Journal Article
Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats
Zhu, Chang Z., Doyle, Kelly J., Nikkel, Arthur L., Olsen, Lauren, Namovic, Marian T., Salte, Katherine, Widomski, Deborah, Su, Zhi, Donnelly-Roberts, Diana L., Gopalakrishnan, Murali M., McGaraughty, Steve
Published in Journal of pharmacological and toxicological methods (01.11.2018)
Published in Journal of pharmacological and toxicological methods (01.11.2018)
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Journal Article
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat
Jarvis, Michael F, Burgard, Edward C, McGaraughty, Steve, Honore, Prisca, Lynch, Kevin, Brennan, Timothy J, Subieta, Alberto, Van Biesen, Tim, Cartmell, Jayne, Bianchi, Bruce, Niforatos, Wende, Kage, Karen, Yu, Haixia, Mikusa, Joe, Wismer, Carol T, Zhu, Chang Z, Chu, Katharine, Lee, Chih-Hung, Stewart, Andrew O, Polakowski, James, Cox, Bryan F, Kowaluk, Elizabeth, Williams, Michael, Sullivan, James, Faltynek, Connie
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.2002)
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A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel Transient Receptor Potential Type V1 Receptor Antagonist, Relieves Pathophysiological Pain Associated with Inflammation and Tissue Injury in Rats
Honore, Prisca, Wismer, Carol T, Mikusa, Joe, Zhu, Chang Z, Zhong, Chengmin, Gauvin, Donna M, Gomtsyan, Arthur, El Kouhen, Rachid, Lee, Chih-Hung, Marsh, Kennan, Sullivan, James P, Faltynek, Connie R, Jarvis, Michael F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2005)
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Journal Article
Characterization of a Cannabinoid CB2 Receptor-Selective Agonist, A-836339 [2,2,3,3-Tetramethyl-cyclopropanecarboxylic Acid [3-(2-Methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], Using in Vitro Pharmacological Assays, in Vivo Pain Models, and Pharmacological Magnetic Resonance Imaging
Yao, Betty B, Hsieh, Gin, Daza, Anthony V, Fan, Yihong, Grayson, George K, Garrison, Tiffany Runyan, El Kouhen, Odile, Hooker, Bradley A, Pai, Madhavi, Wensink, Erica J, Salyers, Anita K, Chandran, Prasant, Zhu, Chang Z, Zhong, Chengmin, Ryther, Keith, Gallagher, Megan E, Chin, Chih-Liang, Tovcimak, Ann E, Hradil, Vincent P, Fox, Gerard B, Dart, Michael J, Honore, Prisca, Meyer, Michael D
Published in The Journal of pharmacology and experimental therapeutics (01.01.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2009)
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Journal Article
Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities
Zhu, Chang Z., Wilson, Sonya G., Mikusa, Joseph P., Wismer, Carol T., Gauvin, Donna M., Lynch, James J., Wade, Carrie L., Decker, Michael W., Honore, Prisca
Published in European journal of pharmacology (15.12.2004)
Published in European journal of pharmacology (15.12.2004)
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Journal Article
Role of central and peripheral mGluR5 receptors in post-operative pain in rats
Zhu, Chang Z., Hsieh, Gin, EI-Kouhen, Odile, Wilson, Sonya G., Mikusa, Joe P., Hollingsworth, Peter R., Chang, Renjie, Moreland, Robert B., Brioni, Jorge, Decker, Michael W., Honore, Prisca
Published in Pain (Amsterdam) (01.03.2005)
Published in Pain (Amsterdam) (01.03.2005)
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Journal Article
Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats
Zhu, Chang Z., Baker, Scott, EI-Kouhen, Odile, Lehto, Sonya G., Hollingsworth, Peter R., Gauvin, Donna M., Hernandez, Gricelda, Zheng, GuoZhu, Chang, Renjie, Moreland, Robert B., Stewart, Andrew O., Brioni, Jorge D., Honore, Prisca
Published in European journal of pharmacology (12.02.2008)
Published in European journal of pharmacology (12.02.2008)
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Journal Article
Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury
Zhang, Xu-Feng, Zhu, Chang Z, Thimmapaya, Rama, Choi, Won S, Honore, Prisca, Scott, Victoria E, Kroeger, Paul E, Sullivan, James P, Faltynek, Connie R, Gopalakrishnan, Murali, Shieh, Char-Chang
Published in Brain research (29.05.2004)
Published in Brain research (29.05.2004)
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Journal Article
Targeting Anti-TGF- β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach
McGaraughty, Steve, Davis-Taber, Rachel A, Zhu, Chang Z, Cole, Todd B, Nikkel, Arthur L, Chhaya, Meha, Doyle, Kelly J, Olson, Lauren M, Preston, Gregory M, Grinnell, Christine M, Salte, Katherine M, Giamis, Anthony M, Luo, Yanping, Sun, Victor, Goodearl, Andrew D, Gopalakrishnan, Murali, Lacy, Susan E
Published in Journal of the American Society of Nephrology (01.12.2017)
Published in Journal of the American Society of Nephrology (01.12.2017)
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Journal Article
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain
Drizin, Irene, Gregg, Robert J., Scanio, Marc J.C., Shi, Lei, Gross, Michael F., Atkinson, Robert N., Thomas, James B., Johnson, Matthew S., Carroll, William A., Marron, Brian E., Chapman, Mark L., Liu, Dong, Krambis, Michael J., Shieh, Char-Chang, Zhang, XuFeng, Hernandez, Gricelda, Gauvin, Donna M., Mikusa, Joseph P., Zhu, Chang Z., Joshi, Shailen, Honore, Prisca, Marsh, Kennan C., Roeloffs, Rosemarie, Werness, Stephen, Krafte, Douglas S., Jarvis, Michael F., Faltynek, Connie R., Kort, Michael E.
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Journal Article
Central and peripheral sites of action for CB 2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats
Hsieh, Gin C, Pai, Madhavi, Chandran, Prasant, Hooker, Bradley A, Zhu, Chang Z, Salyers, Anita K, Wensink, Erica J, Zhan, CenChen, Carroll, William A, Dart, Michael J, Yao, Betty B, Honore, Prisca, Meyer, Michael D
Published in British journal of pharmacology (01.01.2011)
Published in British journal of pharmacology (01.01.2011)
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Journal Article
Effects of A‐317491, a novel and selective P2X 3 /P2X 2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration
McGaraughty, Steve, Wismer, Carol T, Zhu, Chang Z, Mikusa, Joseph, Honore, Prisca, Chu, Katharine L, Lee, Chih‐Hung, Faltynek, Connie R, Jarvis, Michael F
Published in British journal of pharmacology (02.02.2009)
Published in British journal of pharmacology (02.02.2009)
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Journal Article
Potentiation of analgesic efficacy but not side effects: Co-administration of an alpha 4 beta 2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats
Zhu, Chang Z, Chin, Chih-Liang, Rustay, Nathan R, Zhong, Chengmin, Mikusa, Joe, Chandran, Prasant, Salyers, Anita, Gomez, Erica, Simler, Gricelda, Lewis, La Geisha, Gauvin, Donna, Baker, Scott, Pai, Madhavi, Tovcimak, Ann, Brown, Jordan, Komater, Victoria, Fox, Gerard B, Decker, Michael W, Jacobson, Peer B, Gopalakrishnan, Murali, Lee, Chih-Hung, Honore, Prisca
Published in Biochemical pharmacology (15.10.2011)
Published in Biochemical pharmacology (15.10.2011)
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Journal Article
A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury
Zhu, Chang Z., Gopalakrishnan, Sujatha, Doyle, Kelly, Nikkel, Arthur L., Olson, Lauren, Abraham, Vivek C., Leys, Laura, Widomski, Deborah, Salte, Katherine, Putman, Brent, Pratt, Steve, Ma, Ji, Su, Zhi, Gopalakrishnan, Murali, Lee, Chih-Hung, McGaraughty, Steve P.
Published in European journal of pharmacology (05.10.2016)
Published in European journal of pharmacology (05.10.2016)
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Journal Article
Potentiation of analgesic efficacy but not side effects: Co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats
Zhu, Chang Z., Chin, Chih-liang, Rustay, Nathan R., Zhong, Chengmin, Mikusa, Joe, Chandran, Prasant, Salyers, Anita, Gomez, Erica, Simler, Gricelda, Lewis, La Geisha, Gauvin, Donna, Baker, Scott, Pai, Madhavi, Tovcimak, Ann, Brown, Jordan, Komater, Victoria, Fox, Gerard B., Decker, Michael W., Jacobson, Peer B., Gopalakrishnan, Murali, Lee, Chih-Hung, Honore, Prisca
Published in Biochemical pharmacology (15.10.2011)
Published in Biochemical pharmacology (15.10.2011)
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