Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of multiple myeloma
Yoneyama, Tomoki, Kim, Mi-Sook, Piatkov, Konstantin, Wang, Haiqing, Zhu, Andy Z. X
Published in PLoS computational biology (15.07.2022)
Published in PLoS computational biology (15.07.2022)
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Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice
Alsharari, Shakir D, King, Justin R, Nordman, Jacob C, Muldoon, Pretal P, Jackson, Asti, Zhu, Andy Z X, Tyndale, Rachel F, Kabbani, Nadine, Damaj, M Imad
Published in PloS one (10.09.2015)
Published in PloS one (10.09.2015)
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Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking
Tyndale, Rachel F, Zhu, Andy Z X, George, Tony P, Cinciripini, Paul, Hawk, Jr, Larry W, Schnoll, Robert A, Swan, Gary E, Benowitz, Neal L, Heitjan, Daniel F, Lerman, Caryn
Published in PloS one (26.05.2015)
Published in PloS one (26.05.2015)
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Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption
Bergen, Andrew W, Michel, Martha, Nishita, Denise, Krasnow, Ruth, Javitz, Harold S, Conneely, Karen N, Lessov-Schlaggar, Christina N, Hops, Hyman, Zhu, Andy Z X, Baurley, James W, McClure, Jennifer B, Hall, Sharon M, Baker, Timothy B, Conti, David V, Benowitz, Neal L, Lerman, Caryn, Tyndale, Rachel F, Swan, Gary E
Published in PloS one (01.07.2015)
Published in PloS one (01.07.2015)
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CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users
Zhu, Andy Z. X., Renner, Caroline C., Hatsukami, Dorothy K., Benowitz, Neal L., Tyndale, Rachel F.
Published in Addiction (Abingdon, England) (01.10.2013)
Published in Addiction (Abingdon, England) (01.10.2013)
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Fasiglifam (TAK-875) Alters Bile Acid Homeostasis in Rats and Dogs: A Potential Cause of Drug Induced Liver Injury
Wolenski, Francis S, Zhu, Andy Z X, Johnson, Mike, Yu, Shaoxia, Moriya, Yuu, Ebihara, Takuya, Csizmadia, Vilmos, Grieves, Jessica, Paton, Martin, Liao, Mingxiang, Gemski, Christopher, Pan, Liping, Vakilynejad, Majid, Dragan, Yvonne P, Chowdhury, Swapan K, Kirby, Patrick J
Published in Toxicological sciences (01.05.2017)
Published in Toxicological sciences (01.05.2017)
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The Ability of Plasma Cotinine to Predict Nicotine and Carcinogen Exposure is Altered by Differences in CYP2A6: the Influence of Genetics, Race, and Sex
ZHU, Andy Z. X, RENNER, Caroline C, HATSUKAMI, Dorothy K, SWAN, Gary E, LERMAN, Caryn, BENOWITZ, Neal L, TYNDALE, Rachel F
Published in Cancer epidemiology, biomarkers & prevention (01.04.2013)
Published in Cancer epidemiology, biomarkers & prevention (01.04.2013)
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Genome‐wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences
Chenoweth, Meghan J., Ware, Jennifer J., Zhu, Andy Z. X., Cole, Christopher B., Cox, Lisa Sanderson, Nollen, Nikki, Ahluwalia, Jasjit S., Benowitz, Neal L., Schnoll, Robert A., Hawk, Larry W., Cinciripini, Paul M., George, Tony P., Lerman, Caryn, Knight, Joanne, Tyndale, Rachel F.
Published in Addiction (Abingdon, England) (01.03.2018)
Published in Addiction (Abingdon, England) (01.03.2018)
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Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice
Bagdas, Deniz, Muldoon, Pretal P., Zhu, Andy Z.X., Tyndale, Rachel F., Damaj, M. Imad
Published in Neuropharmacology (01.10.2014)
Published in Neuropharmacology (01.10.2014)
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CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people
Binnington, Matthew J, Zhu, Andy Z X, Renner, Caroline C, Lanier, Anne P, Hatsukami, Dorothy K, Benowitz, Neal L, Tyndale, Rachel F
Published in Pharmacogenetics and genomics (01.06.2012)
Published in Pharmacogenetics and genomics (01.06.2012)
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Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation
Zhu, Andy Z X, Binnington, Matthew J, Renner, Caroline C, Lanier, Anne P, Hatsukami, Dorothy K, Stepanov, Irina, Watson, Clifford H, Sosnoff, Connie S, Benowitz, Neal L, Tyndale, Rachel F
Published in Carcinogenesis (New York) (01.01.2013)
Published in Carcinogenesis (New York) (01.01.2013)
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Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective
Heimbach, Tycho, Chen, Yuan, Chen, Jun, Dixit, Vaishali, Parrott, Neil, Peters, Sheila Annie, Poggesi, Italo, Sharma, Pradeep, Snoeys, Jan, Shebley, Mohamad, Tai, Guoying, Tse, Susanna, Upreti, Vijay V., Wang, Ying‐Hong, Tsai, Alice, Xia, Binfeng, Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen
Published in Clinical pharmacology and therapeutics (01.08.2021)
Published in Clinical pharmacology and therapeutics (01.08.2021)
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Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm
Chelliah, Vijayalakshmi, Lazarou, Georgia, Bhatnagar, Sumit, Gibbs, John P., Nijsen, Marjoleen, Ray, Avijit, Stoll, Brian, Thompson, R. Adam, Gulati, Abhishek, Soukharev, Serguei, Yamada, Akihiro, Weddell, Jared, Sayama, Hiroyuki, Oishi, Masayo, Wittemer‐Rump, Sabine, Patel, Chirag, Niederalt, Christoph, Burghaus, Rolf, Scheerans, Christian, Lippert, Jörg, Kabilan, Senthil, Kareva, Irina, Belousova, Natalya, Rolfe, Alex, Zutshi, Anup, Chenel, Marylore, Venezia, Filippo, Fouliard, Sylvain, Oberwittler, Heike, Scholer‐Dahirel, Alix, Lelievre, Helene, Bottino, Dean, Collins, Sabrina C., Nguyen, Hoa Q., Wang, Haiqing, Yoneyama, Tomoki, Zhu, Andy Z.X., Graaf, Piet H., Kierzek, Andrzej M.
Published in Clinical pharmacology and therapeutics (01.03.2021)
Published in Clinical pharmacology and therapeutics (01.03.2021)
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A quantitative systems pharmacology model of plasma kallikrein-kinin system dysregulation in hereditary angioedema
Sexton, Dan, Nguyen, Hoa Q, Juethner, Salomé, Luo, Haobin, Zhang, Zhiwei, Jasper, Paul, Zhu, Andy Z X
Published in Journal of pharmacokinetics and pharmacodynamics (11.05.2024)
Published in Journal of pharmacokinetics and pharmacodynamics (11.05.2024)
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Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion‐aided smoking cessation in African Americans? A moderated mediation analysis
Chenoweth, Meghan J., Peng, Annie R., Zhu, Andy Z. X., Cox, Lisa Sanderson, Nollen, Nikki L., Ahluwalia, Jasjit S., Benowitz, Neal L., Knight, Jo, Swardfager, Walter, Tyndale, Rachel F.
Published in Addiction (Abingdon, England) (01.06.2022)
Published in Addiction (Abingdon, England) (01.06.2022)
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