IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline
Fu, Amy K. Y., Hung, Kwok-Wang, Yuen, Michael Y. F., Zhou, Xiaopu, Mak, Deejay S. Y., Chan, Ivy C. W., Cheung, Tom H., Zhang, Baorong, Fu, Wing-Yu, Liew, Foo Y., Ip, Nancy Y.
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2016)
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Journal Article
Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging
Jiang, Yuanbing, Zhou, Xiaopu, Ip, Fanny C., Chan, Philip, Chen, Yu, Lai, Nicole C.H., Cheung, Kit, Lo, Ronnie M.N., Tong, Estella P.S., Wong, Bonnie W.Y., Chan, Andrew L.T., Mok, Vincent C.T., Kwok, Timothy C.Y., Mok, Kin Y., Hardy, John, Zetterberg, Henrik, Fu, Amy K.Y., Ip, Nancy Y.
Published in Alzheimer's & dementia (01.01.2022)
Published in Alzheimer's & dementia (01.01.2022)
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Journal Article
Polygenic Score Models for Alzheimer's Disease: From Research to Clinical Applications
Zhou, Xiaopu, Li, Yolanda Y T, Fu, Amy K Y, Ip, Nancy Y
Published in Frontiers in neuroscience (29.03.2021)
Published in Frontiers in neuroscience (29.03.2021)
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Journal Article
Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice
Duan, Yangyang, Ye, Tao, Qu, Zhe, Chen, Yuewen, Miranda, Abigail, Zhou, Xiaopu, Lok, Ka-Chun, Chen, Yu, Fu, Amy K. Y., Gradinaru, Viviana, Ip, Nancy Y.
Published in Nature biomedical engineering (01.02.2022)
Published in Nature biomedical engineering (01.02.2022)
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Journal Article
The East Asian Parkinson Disease Genomics Consortium
Mok, Kin Y, Guo, Ji-Feng, Tang, Bei-Sha, Shang, Huifeng, Li, Chunyu, Nguyen, Huong Thi Thanh, Vu, Thi Thanh Huyen, Nguyen, Anh Tuan, Ip, Nancy Y, Fu, Amy KY, Ip, Fanny CF, Zhou, Xiaopu, Cao, Han, Mok, Kin Ying, Hardy, John, Chan, Germaine Hiu Fai, Cheung, Nelson Yuk-Fai, Chan, Phillip, Fong, Wing Chi, Ibrahim, Norlinah Mohamed, Azmin, Shahrul, Abdul Murad, Nor Azian, Sulaiman, Siti Aishah, Desa, Siti Hajar Md, Mohamed, Wael, Koks, Sulev, Pfaff, Abigail, Singleton, Lewis, Kim, Yun Joong, Chung, Seok Jong, Choi, Seong-Min, Chen, Yu, Chen, Yuewen, Ye, Tao, Wu, Yih-Ru, Wu, Hsiu-Chuan, Wu, Ruey-Meei, Lin, Chin-Hsein, Su, Yu-An, Tsai, Mong-Hsun, Shiraishi, Tomotaka, Murakami, Hidetomo, Sengoku, Renpei, Hattori, Nobutaka, Funayama, Manabu, Toda, Tatsushi, Satake, Wataru, Ogaki, Kotaro, Nishioka, Kenya, Singleton, Andrew, Nalls, Mike, Blauwendraat, Cornelis
Published in Lancet neurology (01.12.2021)
Published in Lancet neurology (01.12.2021)
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Journal Article
Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling
Chen, Yu, Liang, Zhuoyi, Fei, Erkang, Chen, Yuewen, Zhou, Xiaopu, Fang, Weiqun, Fu, Wing-Yu, Fu, Amy K Y, Ip, Nancy Y
Published in PloS one (23.07.2015)
Published in PloS one (23.07.2015)
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Journal Article
Multi‐Omics‐Based Autophagy‐Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology
Park, Jong‐Chan, Barahona‐Torres, Natalia, Jang, So‐Yeong, Mok, Kin Y., Kim, Haeng Jun, Han, Sun‐Ho, Cho, Kwang‐Hyun, Zhou, Xiaopu, Fu, Amy K. Y., Ip, Nancy Y., Seo, Jieun, Choi, Murim, Jeong, Hyobin, Hwang, Daehee, Lee, Dong Young, Byun, Min Soo, Yi, Dahyun, Han, Jong Won, Mook‐Jung, Inhee, Hardy, John
Published in Advanced science (01.08.2022)
Published in Advanced science (01.08.2022)
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Journal Article
Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population
Zhou, Xiaopu, Chen, Yu, Ip, Fanny C. F., Lai, Nicole C. H., Li, Yolanda Y. T., Jiang, Yuanbing, Zhong, Huan, Chen, Yuewen, Zhang, Yulin, Ma, Shuangshuang, Lo, Ronnie M. N., Cheung, Kit, Tong, Estella P. S., Ko, Ho, Shoai, Maryam, Mok, Kin Y., Hardy, John, Mok, Vincent C. T., Kwok, Timothy C. Y., Fu, Amy K. Y., Ip, Nancy Y.
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)
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Journal Article
T61. FUNCTIONAL VARIANTS AND HAPLOTYPES IN THE GABBR1 LOCUS SUGGEST POTENTIAL FOR AUTISM SUSCEPTIBILITY
Zhou, Xiaopu, de Aquino, Marla Mendes, Engchuan, Worrawat, Thiruvahindrapuram, Bhooma, MacDonald, Jeffrey R., Trost, Brett, Scherer, Stephen W.
Published in European neuropsychopharmacology (01.10.2024)
Published in European neuropsychopharmacology (01.10.2024)
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Journal Article
81. CHARACTERIZING THE GENETIC ARCHITECTURE OF AUTISM FROM A MULTI-ANCESTRY PERSPECTIVE
de Aquino, Marla Mendes, Xu, Chen Yang, Engchuan, Worrawat, Trost, Brett, Thiruvahindrapuram, Bhooma, de Paiva, Thales Henrique, Zhou, Xiaopu, Tarazona-Santos, Eduardo, Pua, Victor Borda, Scherer, Stephen W.
Published in European neuropsychopharmacology (01.10.2024)
Published in European neuropsychopharmacology (01.10.2024)
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Journal Article
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease
Xu, Peng, Chang, Jerry C, Zhou, Xiaopu, Wang, Wei, Bamkole, Michael, Wong, Eitan, Bettayeb, Karima, Jiang, Lu-Lin, Huang, Timothy, Luo, Wenjie, Xu, Huaxi, Nairn, Angus C, Flajolet, Marc, Ip, Nancy Y, Li, Yue-Ming, Greengard, Paul
Published in The Journal of experimental medicine (02.08.2021)
Published in The Journal of experimental medicine (02.08.2021)
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Journal Article
Using deep learning models to examine the biological impact of polygenic risks for Alzheimer’s disease
Zhou, Xiaopu, Ip, Fanny C. F., Lv, Ge, JIANG, Yuanbing, Cao, Han, Zhong, Huan, Chen, Lei, Fu, Amy K.Y., Ip, Nancy Y.
Published in Alzheimer's & dementia (01.06.2023)
Published in Alzheimer's & dementia (01.06.2023)
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Journal Article
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Zhao, Qianhua, Chen, Keliang, Chen, Yuewen, Hardy, John, Li, Yun, Fu, Amy K. Y., Guo, Qihao, Ip, Nancy Y.
Published in Proceedings of the National Academy of Sciences - PNAS (20.02.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (20.02.2018)
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Journal Article
Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development
Liang, Zhuoyi, Ye, Tao, Zhou, Xiaopu, Lai, Kwok-On, Fu, Amy K Y, Ip, Nancy Y
Published in The Journal of neuroscience (11.11.2015)
Published in The Journal of neuroscience (11.11.2015)
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Journal Article
IDENTIFICATION OF PROTEIN PHOSPHORYLATION ASSOCIATED WITH ABERRANT SYNAPTIC FUNCTION IN ALZHEIMER'S DISEASE
Chen, Yuewen, Xu, Jinying, Zhou, Xiaopu, Liu, Saijuan, Zhang, Yulin, Ma, Shuangshuang, Fu, Amy K.Y., Ip, Nancy Y., Chen, Yu
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
P4‐128: IDENTIFICATION OF PROTEIN PHOSPHORYLATION ASSOCIATED WITH ABERRANT SYNAPTIC FUNCTION IN ALZHEIMER'S DISEASE
Chen, Yuewen, Xu, Jinying, Zhou, Xiaopu, Liu, Saijuan, Zhang, Yulin, Ma, Shuangshuang, Fu, Amy K.Y., Ip, Nancy Y., Chen, Yu
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE‐ε4 in Alzheimer’s disease
JIANG, Yuanbing, Zhou, Xiaopu, Wong, Hiu Yi, Li, Ouyang, Ip, Fanny C. F., Chau, Vicky M.N., Lau, Shun‐Fat, Wu, Wei, Wong, Daniel Y.K., Seo, Heukjin, Fu, Wing‐Yu, Lai, Nicole Chit Hang, Chen, Yuewen, Chen, Yu, Tong, Estella Pui‐Sze, Mok, Vincent C.T., Kwok, Timothy CY, Mok, Kin Y, Shoai, Maryam, Lehallier, Benoit, Moran‐Losada, Patricia, O’Brien, Eleanor, Porter, Tenielle, Laws, Simon M, Hardy, John A., Wyss‐Coray, Tony, Masters, Colin L., Fu, Amy K.Y., Ip, Nancy Y.
Published in Alzheimer's & dementia (01.06.2023)
Published in Alzheimer's & dementia (01.06.2023)
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