Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer
Gustin, Darin James, McGee, Lawrence, Yan, Xuelei, Gribble, jr. Michael William, Beck, Hilary Plake, McMinn, Dustin, Zhu, Jiang, Chen, Xiaoqi, Heath, Julie Anne, Li, Zhihong, Mihalic, Jeffrey Thomas, Jiao, Xianjun, Lai, SuJen, Fu, Zice, Ma, Zhihua, Deignan, Jeffery, Wang, Xiaodong, Huang, Xin, Eksterowicz, John, Roveto, Philip Marley, Yu, Ming, Kayser, Frank, Kopecky, David John, Gonzalez Lopez de Turiso, Felix, McIntosh, Joel, Connors, Richard Victor, Olson, Steven Howard, Gonzalez Buenrostro, Ana, Duquette, Jason, Fu, Jiasheng, Liu, Jiwen, Low, Jonathan Dante, Li, Yihong, Fox, Brian Matthew, Bartberger, Michael David, Sun, Daqing, Wang, Yingcai, Medina, Julio Cesar, Fisher, Benjamin, Johnson, Michael, Lucas, Brian Stuart, Rew, Yosup
Year of Publication 14.11.2018
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Year of Publication 14.11.2018
Patent
Methods for preparing triazole agonists of the APJ receptor
Nishimura Nobuko, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Ma Zhihua, Dransfield Paul John, Medina Julio C, Farrell Robert P, Heath Julie Anne, DeBenedetto Mikkel V, Chen Xiaoqi, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Hedley Simon J, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 05.09.2017
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Year of Publication 05.09.2017
Patent
Triazole agonists of the APJ receptor
Nishimura Nobuko, Cheng Alan C, Kayser Frank, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Khakoo Aarif Yusuf, Ma Zhihua, Dransfield Paul John, Swaminath Gayathri, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Yeh Wen-Chen, Hedley Simon J, Chen Yinhong, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 16.01.2018
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Year of Publication 16.01.2018
Patent
Intermediates for preparing triazole agonists of the APJ receptor
Nishimura Nobuko, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Ma Zhihua, Dransfield Paul John, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Hedley Simon J, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 23.05.2017
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Year of Publication 23.05.2017
Patent
Triazole agonists of the APJ receptor
Cheng, Alan C, Houze, Jonathan, McGee, Lawrence R, Olson, Steven H, Chen, Xiaoqi, Heath, Julie Anne, Khakoo, Aarif Yusuf, Yang, Kevin, Fu, Zice, Kaller, Matthew R, Deignan, Jeffrey, Ma, Zhihua, Wang, Xiaodong, Medina, Julio C, Dransfield, Paul John, Swaminath, Gayathri, Horne, Daniel B, Kopecky, David John, Kayser, Frank, Farrell, Robert P, Chen, Ning, Hedley, Simon J, Connors, Richard V, Yeh, Wen-Chen, Debenedetto, Mikkel V, Mihalic, Jeffrey T, Nishimura, Nobuko, Judd, Ted C, Pattaropong, Vatee, Chen, Yinhong, Du, Xiaohui, Lai, Su-Jen
Year of Publication 30.11.2017
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Year of Publication 30.11.2017
Patent
COMPOSTOS AGONISTAS DE TRIAZOL DO RECEPTOR APJ, COMPOSIÇÕES E USOS RELACIONADOS
KEVIN YANG, XIAOHUI DU, DAVID JOHN KOPECKY, SIMON J. HEDLEY, ROBERT P. FARRELL, NING CHEN, RICHARD V. CONNORS, SU-JEN LAI, AARIF YUSUF KHAKOO, TED C. JUDD, FRANK KAYSER, JEFFREY T. MIHALIC, LAWRENCE R. MCGEE, JULIE ANNE HEATH, XIAOQI CHEN, WENN YEH, ZHIHUA MA, XIAODONG WANG, YINHONG CHEN, MATTHEW R. KALLER, GAYATHRI SWAMINATH, JEFFREY DEIGNAN, NOBUKO NISHIMURA, JONATHAN HOUZE, STEVEN H. OLSON, VATEE PATTAROPONG, ALAN C. CHENG, MIKKEL V. DEBENEDETTO, JULIO C. MEDINA, DANIEL B. HORNE, PAUL JOHN DRANSFIELD, ZICE FU
Year of Publication 14.03.2023
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Year of Publication 14.03.2023
Patent
Triazole agonists of the APJ receptor
Nishimura Nobuko, Cheng Alan C, Kayser Frank, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Khakoo Aarif Yusuf, Ma Zhihua, Dransfield Paul John, Swaminath Gayathri, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Yeh Wen-Chen, Hedley Simon J, Chen Yinhong, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 29.08.2017
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Year of Publication 29.08.2017
Patent
N-Heterocyclic Carbenes Catalyzed Phospho-Aldol Reaction of Aldehydes
He, Lin, Cai, Zhihua, Ma, Xiaowei, Du, Guangfen
Published in Chinese journal of chemistry (01.12.2013)
Published in Chinese journal of chemistry (01.12.2013)
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Journal Article
Triazole agonists of the APJ receptor
Nishimura Nobuko, Cheng Alan C, Kayser Frank, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Ma Zhihua, Dransfield Paul John, Swaminath Gayathri, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Hedley Simon J, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 23.05.2017
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Year of Publication 23.05.2017
Patent
Triazole agonists of the APJ receptor
Nishimura Nobuko, Cheng Alan C, Kayser Frank, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Khakoo Aarif Yusuf, Ma Zhihua, Dransfield Paul John, Swaminath Gayathri, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Yeh Wen-Chen, Hedley Simon J, Chen Yinhong, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 21.02.2017
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Year of Publication 21.02.2017
Patent
TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Nishimura Nobuko, Cheng Alan C, Kayser Frank, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Khakoo Aarif Yusuf, Ma Zhihua, Dransfield Paul John, Swaminath Gayathri, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Yeh Wen-Chen, Hedley Simon J, Chen Yinhong, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 16.02.2017
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Year of Publication 16.02.2017
Patent
TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Nishimura Nobuko, Cheng Alan C, Kayser Frank, Mihalic Jeffrey T, Houze Jonathan, Horne Daniel B, Deignan Jeffrey, McGee Lawrence R, Du Xiaohui, Kopecky David John, Yang Kevin, Khakoo Aarif Yusuf, Ma Zhihua, Dransfield Paul John, Swaminath Gayathri, Medina Julio C, Farrell Robert P, Heath Julie Anne, Chen Xiaoqi, Debenedetto Mikkel V, Chen Ning, Olson Steven H, Kaller Matthew R, Wang Xiaodong, Lai Su-Jen, Pattaropong Vatee, Yeh Wen-Chen, Hedley Simon J, Chen Yinhong, Fu Zice, Judd Ted C, Connors Richard V
Year of Publication 24.11.2016
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Year of Publication 24.11.2016
Patent
Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer
Sun Daqing, Kayser Frank, Connors Richard Victor, Duquette Jason A, Yu Ming, Gonzalez Lopez De Turiso Felix, Deignan Jeffrey, McGee Lawrence R, Bartberger Michael D, Huang Xin, Kopecky David John, Liu Jiwen, Heath Julie A, Wang Yingcai, Fu Jiasheng, Ma Zhihua, Eksterowicz John, Gustin Darin J, Gribble, Jr. Michael W, Rew Yosup, Fox Brian M, Beck Hilary Plake, Zhu Jiang, Medina Julio C, Fisher Benjamin, Li Yihong, Chen Xiaoqi, Roveto Philip M, Lucas Brian S, Jiao XianYun, McMinn Dustin L, Olson Steven H, Wang Xiaodong, Yan Xuelei, Lai SuJen, Low Jonathan D, Gonzalez Buenrostro Ana, McIntosh Joel, Johnson Michael G, Mihalic Jeffrey Thomas, Li Zhihong, Fu Zice
Year of Publication 14.03.2017
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Year of Publication 14.03.2017
Patent
TRIAZOLE AGONISTS OF THE APJ RECEPTOR
FU Zice, HOUZE Jonathan, WANG Xiaodong, HORNE Daniel B, DEIGNAN Jeffrey, HEDLEY Simon J, DRANSFIELD Paul John, NISHIMURA Nobuko, MCGEE Lawrence R, Ma Zhihua, KHAKOO Aarif Yusuf, KALLER Matthew R, KAYSER Frank, CONNORS Richard V, CHEN Xiaoqi, DEBENEDETTO Mikkel V, SWAMINATH Gayathri, FARRELL Robert P, MIHALIC Jeffrey T, KOPECKY David John, OLSON Steven H, YANG Kevin, MEDINA Julio C, CHENG Alan C, PATTAROPONG Vatee, CHEN Ning, DU Xiaohui, YEH Wen-Chen, Judd Ted C, LAI Su-Jen, CHEN Yinhong, HEATH Julie Anne
Year of Publication 16.02.2017
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Year of Publication 16.02.2017
Patent