The combination of berberine and isoliquiritigenin synergistically improved adipose inflammation and obesity‐induced insulin resistance
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Published in Phytotherapy research (01.08.2024)
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Dual targeting of SREBP2 and ERRα by carnosic acid suppresses RANKL-mediated osteoclastogenesis and prevents ovariectomy-induced bone loss
Zheng, Zu-Guo, Cheng, Hui-Min, Zhou, Ya-Ping, Zhu, Si-Tong, Thu, Pyone Myat, Li, Hui-Jun, Li, Ping, Xu, Xiaojun
Published in Cell death and differentiation (01.07.2020)
Published in Cell death and differentiation (01.07.2020)
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Statins induce skeletal muscle atrophy via GGPP depletion-dependent myostatin overexpression in skeletal muscle and brown adipose tissue
Wang, Lai, Zheng, Zu-Guo, Meng, Lingchang, Zhu, Lijun, Li, Ping, Chen, Jun, Yang, Hua
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Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
Zheng, Zu-Guo, Zhang, Xin, Liu, Xiao-Xiao, Jin, Xiu-Xiu, Dai, Lunzhi, Cheng, Hui-Min, Jing, Dan, Thu, Pyone Myat, Zhang, Mu, Li, Hongyang, Zhu, Jing, Liu, Chang, Xue, Bin, Li, Yu, Chen, Ligong, Peng, Cheng, Zhu, Weiliang, Wang, Lin, Liu, Junli, Li, Hui-Jun, Li, Ping, Xu, Xiaojun
Published in Theranostics (01.01.2019)
Published in Theranostics (01.01.2019)
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Advancing targeted protein degradation for metabolic diseases therapy
Zhou, Qian-Qian, Xiao, Hai-Tao, Yang, Fan, Wang, Yong-Dan, Li, Ping, Zheng, Zu-Guo
Published in Pharmacological research (01.02.2023)
Published in Pharmacological research (01.02.2023)
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Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway
Zheng, Zu-Guo, Zhu, Si-Tong, Cheng, Hui-Min, Zhang, Xin, Cheng, Gang, Thu, Pyone Myat, Wang, Supeng Perry, Li, Hui-Jun, Ding, Ming, Qiang, Lei, Chen, Xiao-Wei, Zhong, Qing, Li, Ping, Xu, Xiaojun
Published in Autophagy (03.07.2021)
Published in Autophagy (03.07.2021)
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Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway
Zhang, Mu, Qian, Cheng, Zheng, Zu-Guo, Qian, Fei, Wang, Yanyan, Thu, Pyone Myat, Zhang, Xin, Zhou, Yaping, Tu, Lifan, Liu, Qingling, Li, Hui-Jun, Yang, Hua, Li, Ping, Xu, Xiaojun
Published in Theranostics (01.01.2018)
Published in Theranostics (01.01.2018)
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Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis
Zheng, Zu-Guo, Xu, Yin-Yue, Liu, Wen-Ping, Zhang, Yang, Zhang, Chong, Liu, Han-Ling, Zhang, Xiao-Yu, Liu, Run-Zhou, Zhang, Yi-Ping, Shi, Meng-Ying, Yang, Hua, Li, Ping
Published in Cell metabolism (03.01.2023)
Published in Cell metabolism (03.01.2023)
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Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis
Thu, Pyone Myat, Zheng, Zu-Guo, Zhou, Ya-Ping, Wang, Yan-Yan, Zhang, Xin, Jing, Dan, Cheng, Hui-Min, Li, Ji, Li, Ping, Xu, Xiaojun
Published in European journal of pharmacology (05.05.2019)
Published in European journal of pharmacology (05.05.2019)
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Baohuoside I inhibits FXR signaling pathway to interfere with bile acid homeostasis via targeting ER α degradation
Zhao, Zhen, Yang, Lu-Lu, Wang, Qiao-Lei, Du, Jin-Fa, Zheng, Zu-Guo, Jiang, Yan, Li, Ping, Li, Hui-Jun
Published in Cell biology and toxicology (01.08.2023)
Published in Cell biology and toxicology (01.08.2023)
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Anhydroicaritin, a SREBPs inhibitor, inhibits RANKL-induced osteoclastic differentiation and improves diabetic osteoporosis in STZ-induced mice
Zheng, Zu-Guo, Zhang, Xin, Zhou, Ya-Ping, Lu, Chong, Thu, Pyone Myat, Qian, Cheng, Zhang, Mu, Li, Ping, Li, Hui-Jun, Xu, Xiaojun
Published in European journal of pharmacology (15.08.2017)
Published in European journal of pharmacology (15.08.2017)
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Rapid discovery of cyclopamine analogs from Fritillaria and Veratrum plants using LC-Q-TOF-MS and LC-QqQ-MS
Du, Yuan, Zheng, Zu-Guo, Yu, Yue, Wu, Zi-Tian, Liang, Dan, Li, Ping, Jiang, Yan, Li, Hui-Jun
Published in Journal of pharmaceutical and biomedical analysis (05.08.2017)
Published in Journal of pharmaceutical and biomedical analysis (05.08.2017)
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Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation
Zheng, Zu-Guo, Zhou, Ya-Ping, Zhang, Xin, Thu, Pyone Myat, Xie, Zhi-Shen, Lu, Chong, Pang, Tao, Xue, Bin, Xu, Da-Qian, Chen, Yan, Chen, Xiao-Wei, Li, Hui-Jun, Xu, Xiaojun
Published in Biochemical pharmacology (15.12.2016)
Published in Biochemical pharmacology (15.12.2016)
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Evaluation of structure–activity relationships of ginsenosides against amyloid β induced pathological behaviours in transgenic Caenorhabditis elegans
Zhang, Mu, Qian, Fei, Liu, Qingling, Qian, Cheng, Thu, Pyone Myat, Wang, Yanyan, Zheng, Zu-Guo, Yang, Hua, Li, Ping, Xu, Xiaojun
Published in RSC advances (01.01.2017)
Published in RSC advances (01.01.2017)
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Simiao Wan alleviates obesity-associated insulin resistance via PKCε/IRS-1/PI3K/Akt signaling pathway based on network pharmacology analysis and experimental validation
Jin, Jing, Xu, Yin-Yue, Liu, Wen-Ping, Hu, Ke-Hua, Xue, Ning, Zheng, Zu-Guo
Published in Traditional medicine research (01.10.2023)
Published in Traditional medicine research (01.10.2023)
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Advances in research on hypolipidemic mechanism of phytosterols
Lu, Jing-Xia, Zheng, Zu-Guo, Xu, Zhi-Meng, Yang, Hua, Li, Ping
Published in Zhongguo zhongyao zazhi (01.11.2019)
Published in Zhongguo zhongyao zazhi (01.11.2019)
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