TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses
Burkly, Linda C., Michaelson, Jennifer S., Zheng, Timothy S.
Published in Immunological reviews (01.11.2011)
Published in Immunological reviews (01.11.2011)
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Journal Article
TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease
Gomez, Ivan G, Roach, Allie M, Nakagawa, Naoki, Amatucci, Aldo, Johnson, Bryce G, Dunn, Kadeshia, Kelly, Mark C, Karaca, Gamze, Zheng, Timothy S, Szak, Suzanne, Peppiatt-Wildman, Claire M, Burkly, Linda C, Duffield, Jeremy S
Published in Journal of the American Society of Nephrology (01.12.2016)
Published in Journal of the American Society of Nephrology (01.12.2016)
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Journal Article
Identification of regulators of the myofibroblast phenotype of primary dermal fibroblasts from early diffuse systemic sclerosis patients
Chadli, Loubna, Sotthewes, Britt, Li, Kejie, Andersen, Stefan N., Cahir-McFarland, Ellen, Cheung, Marc, Cullen, Patrick, Dorjée, Annemarie, de Vries-Bouwstra, Jeska K., Huizinga, Tom W. J., Fischer, David F., DeGroot, Jeroen, Viney, Joanne L., Zheng, Timothy S., Aarbiou, Jamil, Gardet, Agnes
Published in Scientific reports (14.03.2019)
Published in Scientific reports (14.03.2019)
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Journal Article
TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease
Pappu, Bhanu P, Borodovsky, Anna, Zheng, Timothy S, Yang, Xuexian, Wu, Ping, Dong, Xingwen, Weng, Shawn, Browning, Beth, Scott, Martin L, Ma, Li, Su, Lihe, Tian, Qiang, Schneider, Pascal, Flavell, Richard A, Dong, Chen, Burkly, Linda C
Published in The Journal of experimental medicine (12.05.2008)
Published in The Journal of experimental medicine (12.05.2008)
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Journal Article
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Anti-TWEAK Monoclonal Antibody in Patients With Rheumatoid Arthritis
Wisniacki, Nicolas, MD, PhD, Amaravadi, Lakshmi, PhD, Galluppi, Gerald R., PhD, Zheng, Timothy S., PhD, Zhang, Ray, PhD, Kong, Jessica, PhD, Burkly, Linda C., PhD
Published in Clinical therapeutics (01.08.2013)
Published in Clinical therapeutics (01.08.2013)
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Journal Article
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction
Novoyatleva, Tatyana, Schymura, Yves, Janssen, Wiebke, Strobl, Frederic, Swiercz, Jakub M., Patra, Chinmoy, Posern, Guido, Wietelmann, Astrid, Zheng, Timothy S., Schermuly, Ralph T., Engel, Felix B.
Published in Basic research in cardiology (01.03.2013)
Published in Basic research in cardiology (01.03.2013)
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Journal Article
TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity
Yadava, Ramesh S, Foff, Erin P, Yu, Qing, Gladman, Jordan T, Zheng, Timothy S, Mahadevan, Mani S
Published in PloS one (22.02.2016)
Published in PloS one (22.02.2016)
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Journal Article
A Novel Role for Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) in the Development of Cardiac Dysfunction and Failure
JAIN, Mohit, JAKUBOWSKI, Aniela, SAM, Flora, AMBROSE, Christine, PARR, Michael, CROWELL, Thomas, LINCECUM, John M, WANG, Monica Z, HSU, Yen-Ming, ZHENG, Timothy S, MICHAELSON, Jennifer S, LIAO, Ronglih, LEI CUI, BURKLY, Linda C, JIANRU SHI, LIHE SU, BAUER, Michael, JIAN GUAN, CHEE CHEW LIM, NAITO, Yoshiro, THOMPSON, Jeffrey S
Published in Circulation (New York, N.Y.) (21.04.2009)
Published in Circulation (New York, N.Y.) (21.04.2009)
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Journal Article
TWEAK Is a Novel Arthritogenic Mediator
Perper, Stuart J, Browning, Beth, Burkly, Linda C, Weng, Shawn, Gao, Cindy, Giza, Keith, Su, Lihe, Tarilonte, Leticia, Crowell, Thomas, Rajman, Luis, Runkel, Laura, Scott, Martin, Atkins, Gerald J, Findlay, David M, Zheng, Timothy S, Hess, Henry
Published in Journal of Immunology (15.08.2006)
Published in Journal of Immunology (15.08.2006)
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Journal Article
Fn14-Fc Fusion Protein Regulates Atherosclerosis in ApoE−/− Mice and Inhibits Macrophage Lipid Uptake In Vitro
Schapira, Kitty, Burkly, Linda C, Zheng, Timothy S, Wu, Ping, Groeneweg, Mathijs, Rousch, Mat, Kockx, Mark M, Daemen, Mat J.A.P, Heeneman, Sylvia
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2009)
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Journal Article
Expression of TWEAK and Its Receptor Fn14 in the Multiple Sclerosis Brain: Implications for Inflammatory Tissue Injury
Serafini, Barbara, Magliozzi, Roberta, Rosicarelli, Barbara, Reynolds, Richard, Zheng, Timothy S, Aloisi, Francesca
Published in Journal of neuropathology and experimental neurology (01.12.2008)
Published in Journal of neuropathology and experimental neurology (01.12.2008)
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Journal Article
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
Flavell, Richard A, Zheng, Timothy S, Hunot, Stéphane, Kuida, Keisuke, Momoi, Takashi, Srinivasan, Anu, Nicholson, Donald W, Lazebnik, Yuri
Published in Nature medicine (01.11.2000)
Published in Nature medicine (01.11.2000)
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Journal Article
Genetic architecture of human fibrotic diseases: disease risk and disease progression
Gardet, Agnès, Zheng, Timothy S, Viney, Joanne L
Published in Frontiers in pharmacology (18.12.2013)
Published in Frontiers in pharmacology (18.12.2013)
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Journal Article
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
Kuida, Keisuke, Zheng, Timothy S, Na, Songqing, Kuan, Chia-Yi, Yang, Di, Karasuyama, Hajime, Rakic, Pasko, Flavell, Richard A
Published in Nature (London) (28.11.1996)
Published in Nature (London) (28.11.1996)
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Journal Article
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration
Girgenrath, Mahasweta, Weng, Shawn, Kostek, Christine A, Browning, Beth, Wang, Monica, Brown, Sharron AN, Winkles, Jeffrey A, Michaelson, Jennifer S, Allaire, Norm, Schneider, Pascal, Scott, Martin L, Hsu, Yen-ming, Yagita, Hideo, Flavell, Richard A, Miller, Jeffrey Boone, Burkly, Linda C, Zheng, Timothy S
Published in The EMBO journal (13.12.2006)
Published in The EMBO journal (13.12.2006)
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Journal Article
Tweak induces mammary epithelial branching morphogenesis
MICHAELSON, Jennifer S, CHO, Sandy, BROWNING, Beth, ZHENG, Timothy S, LINCECUM, John M, WANG, Monica Z, HSU, Yen-Ming, BURKLY, Linda C
Published in Oncogene (14.04.2005)
Published in Oncogene (14.04.2005)
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Journal Article
Caspase-3 Controls both Cytoplasmic and Nuclear Events Associated with Fas-Mediated Apoptosis in vivo
Zheng, Timothy S., Schlosser, Stephan F., Dao, Tao, Hingorani, Ravi, Crispe, I. Nicholas, Boyer, James L., Flavell, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.1998)
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Journal Article
Identification of a New Murine Tumor Necrosis Factor Receptor Locus That Contains Two Novel Murine Receptors for Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)
Schneider, Pascal, Olson, Dian, Tardivel, Aubry, Browning, Beth, Lugovskoy, Alexey, Gong, DaHai, Dobles, Max, Hertig, Sylvie, Hofmann, Kay, Van Vlijmen, Herman, Hsu, Yen-Ming, Burkly, Linda C, Tschopp, Jurg, Zheng, Timothy S
Published in The Journal of biological chemistry (14.02.2003)
Published in The Journal of biological chemistry (14.02.2003)
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