Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
Bosse, Kristopher R., Raman, Pichai, Zhu, Zhongyu, Lane, Maria, Martinez, Daniel, Heitzeneder, Sabine, Rathi, Komal S., Kendsersky, Nathan M., Randall, Michael, Donovan, Laura, Morrissy, Sorana, Sussman, Robyn T., Zhelev, Doncho V., Feng, Yang, Wang, Yanping, Hwang, Jennifer, Lopez, Gonzalo, Harenza, Jo Lynne, Wei, Jun S., Pawel, Bruce, Bhatti, Tricia, Santi, Mariarita, Ganguly, Arupa, Khan, Javed, Marra, Marco A., Taylor, Michael D., Dimitrov, Dimiter S., Mackall, Crystal L., Maris, John M.
Published in Cancer cell (11.09.2017)
Published in Cancer cell (11.09.2017)
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Journal Article
Chimeric antigen receptor-T cells are effective against CEACAM5 expressing non-small cell lung cancer cells resistant to antibody-drug conjugates
Kim, Ye-Jin, Li, Wei, Zhelev, Doncho V, Mellors, John W, Dimitrov, Dimiter S, Baek, Du-San
Published in Frontiers in oncology (27.02.2023)
Published in Frontiers in oncology (27.02.2023)
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Journal Article
GPC2 antibody–drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies
Pascual-Pasto, Guillem, McIntyre, Brendan, Shraim, Rawan, Buongervino, Samantha N, Erbe, Amy K, Zhelev, Doncho V, Sadirova, Shakhnozakhon, Giudice, Anna M, Martinez, Daniel, Garcia-Gerique, Laura, Dimitrov, Dimiter S, Sondel, Paul M, Bosse, Kristopher R
Published in Journal for immunotherapy of cancer (01.12.2022)
Published in Journal for immunotherapy of cancer (01.12.2022)
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Journal Article
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection
Li, Wei, Chen, Chuan, Drelich, Aleksandra, Martinez, David R., Gralinski, Lisa E., Sun, Zehua, Schäfer, Alexandra, Kulkarni, Swarali S., Liu, Xianglei, Leist, Sarah R., Zhelev, Doncho V., Zhang, Liyong, Kim, Ye-Jin, Peterson, Eric C., Conard, Alex, Mellors, John W., Tseng, Chien-Te K., Falzarano, Darryl, Baric, Ralph S., Dimitrov, Dimiter S.
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2020)
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Journal Article
Antibody-Drug Conjugate Efficacy in Neuroblastoma: Role of Payload, Resistance Mechanisms, Target Density, and Antibody Internalization
Buongervino, Samantha, Lane, Maria V, Garrigan, Emily, Zhelev, Doncho V, Dimitrov, Dimiter S, Bosse, Kristopher R
Published in Molecular cancer therapeutics (01.11.2021)
Published in Molecular cancer therapeutics (01.11.2021)
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Journal Article
A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope
Raman, Swetha, Buongervino, Samantha N, Lane, Maria V, Zhelev, Doncho V, Zhu, Zhongyu, Cui, Hong, Martinez, Benjamin, Martinez, Daniel, Wang, Yanping, Upton, Kristen, Patel, Khushbu, Rathi, Komal S, Navia, Carmen T, Harmon, Daniel B, Li, Yimei, Pawel, Bruce, Dimitrov, Dimiter S, Maris, John M, Julien, Jean-Philippe, Bosse, Kristopher R
Published in Cell reports. Medicine (20.07.2021)
Published in Cell reports. Medicine (20.07.2021)
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Journal Article
Function and regulation of chemoattractant receptors
Haribabu, B, Richardson, R M, Verghese, M W, Barr, A J, Zhelev, D V, Snyderman, R
Published in Immunologic research (01.01.2000)
Published in Immunologic research (01.01.2000)
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Journal Article
Controlled Pseudopod Extension of Human Neutrophils Stimulated with Different Chemoattractants
Zhelev, Doncho V., Alteraifi, Abdullatif M., Chodniewicz, David
Published in Biophysical journal (01.07.2004)
Published in Biophysical journal (01.07.2004)
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Journal Article
Interaction of Synthetic HA2 Influenza Fusion Peptide Analog with Model Membranes
Zhelev, Doncho V., Stoicheva, Natalia, Scherrer, Peter, Needham, David
Published in Biophysical journal (01.07.2001)
Published in Biophysical journal (01.07.2001)
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Journal Article
Abstract A26: Characterization and development of a GPC2 ADC for neuroblastoma and other cancers
Bosse, Kristopher R., Raman, Swetha, Buongervino, Samantha, Lane, Maria, Upton, Kristen, Cui, Hong, Martinez, Benjamin, Martinez, Daniel, Zhelev, Doncho V., Pawel, Bruce, Dimitrov, Dimiter S., Julien, Jean-Philippe, Maris, John M.
Published in Cancer research (Chicago, Ill.) (15.07.2020)
Published in Cancer research (Chicago, Ill.) (15.07.2020)
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Journal Article
Abstract 4636: The antibody-drug conjugate D3-GPC2-PBD potently eradicates neuroblastoma patient-derived xenografts
Bosse, Kristopher R., Zhu, Zhongyu, Lane, Maria, Martinez, Daniel, DeLong, John, Zhelev, Doncho V., Feng, Yang, Wang, Yanping, Hwang, Jennifer, Dimitrov, Dimiter S., Maris, John
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Effect of membrane area expansion on the cortical tension of human neutrophils
Albarran, Brian, Ting-Beall, HPing, Zhelev, Doncho V, Hochmuth, Robert M
Published in Annals of biomedical engineering (01.01.2000)
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Published in Annals of biomedical engineering (01.01.2000)
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