Indole RSK inhibitors. Part 1: Discovery and initial SAR
Boyer, Stephen J., Burke, Jennifer, Guo, Xin, Kirrane, Thomas M., Snow, Roger J., Zhang, Yunlong, Sarko, Chris, Soleymanzadeh, Lida, Swinamer, Alan, Westbrook, John, DiCapua, Frank, Padyana, Anil, Cogan, Derek, Gao, Amy, Xiong, Zhaoming, Madwed, Jeffrey B., Kashem, Mohammed, Kugler, Stanley, O’Neill, Margaret M.
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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Journal Article
Indole Inhibitors of MMP-13 for Arthritic Disorders
Taylor, Steven J, Abeywardane, Asitha, Liang, Shuang, Xiong, Zhaoming, Proudfoot, John R, Farmer, Bennett Sandy, Gao, Donghong A, Heim-Riether, Alexander, Smith-Keenan, Lana Louise, Muegge, Ingo, Yu, Yang, Zhang, Qiang, Souza, Donald, Panzenbeck, Mark, Goldberg, Daniel, Hill-Drzewi, Melissa, Margarit, Mariana, Collins, Brandon, Li, John Xiang, Zuvela-Jelaska, Ljiljana, Li, Jun, Farrow, Neil A
Published in ACS omega (27.07.2021)
Published in ACS omega (27.07.2021)
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Journal Article
Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors
Heim-Riether, Alexander, Taylor, Steven J., Liang, Shuang, Gao, Donghong Amy, Xiong, Zhaoming, Michael August, E., Collins, Brandon K., Farmer, Bennett T., Haverty, Kathleen, Hill-Drzewi, Melissa, Junker, Hans-Dieter, Mariana Margarit, S., Moss, Neil, Neumann, Thomas, Proudfoot, John R., Keenan, Lana Smith, Sekul, Renate, Zhang, Qiang, Li, Jun, Farrow, Neil A.
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
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Journal Article
Synthesis and SAR studies of indole-based MK2 inhibitors
Xiong, Zhaoming, Gao, Donghong Amy, Cogan, Derek A., Goldberg, Daniel R., Hao, Ming-Hong, Moss, Neil, Pack, Edward, Pargellis, Chris, Skow, Donna, Trieselmann, Thomas, Werneburg, Brian, White, Andre
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Journal Article
Exploration of cathepsin S inhibitors characterized by a triazole P1–P2 amide replacement
Moss, Neil, Xiong, Zhaoming, Burke, Mike, Cogan, Derek, Gao, Donghong A., Haverty, Kathleen, Heim-Riether, Alexander, Hickey, Eugene R., Nagaraja, Raj, Netherton, Matthew, O’Shea, Kathy, Ramsden, Philip, Schwartz, Racheline, Shih, Daw-Tsun, Ward, Yancey, Young, Erick, Zhang, Qing
Published in Bioorganic & medicinal chemistry letters (01.12.2012)
Published in Bioorganic & medicinal chemistry letters (01.12.2012)
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Journal Article
SAR studies of non-zinc-chelating MMP-13 inhibitors: Improving selectivity and metabolic stability
Gao, Donghong Amy, Xiong, Zhaoming, Heim-Riether, Alexander, Amodeo, Laura, August, E. Michael, Cao, Xianhua, Ciccarelli, Leonard, Collins, Brandon K., Harrington, Kyle, Haverty, Kathleen, Hill-Drzewi, Melissa, Li, Xiang, Liang, Shuang, Margarit, Steluta Mariana, Moss, Neil, Nagaraja, Nelamangala, Proudfoot, John, Roman, Rene, Schlyer, Sabine, Keenan, Lana Smith, Taylor, Steven, Wellenzohn, Bernd, Wiedenmayer, Dieter, Li, Jun, Farrow, Neil A.
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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Journal Article
Discovery and Optimization of p38 Inhibitors via Computer-Assisted Drug Design
Goldberg, Daniel R, Hao, Ming-Hong, Qian, Kevin C, Swinamer, Alan D, Gao, Donghong A, Xiong, Zhaoming, Sarko, Chris, Berry, Angela, Lord, John, Magolda, Ronald L, Fadra, Tazmeen, Kroe, Rachel R, Kukulka, Alison, Madwed, Jeffrey B, Martin, Leslie, Pargellis, Christopher, Skow, Donna, Song, Jinhua J, Tan, Zhulin, Torcellini, Carol A, Zimmitti, Clare S, Yee, Nathan K, Moss, Neil
Published in Journal of medicinal chemistry (23.08.2007)
Published in Journal of medicinal chemistry (23.08.2007)
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Journal Article
Discovery and characterization of the N-phenyl- N′-naphthylurea class of p38 kinase inhibitors
Cirillo, Pier F., Hickey, Eugene R., Moss, Neil, Breitfelder, Steffen, Betageri, Raj, Fadra, Tazmeen, Gaenzler, Faith, Gilmore, Thomas, Goldberg, Daniel R., Kamhi, Victor, Kirrane, Thomas, Kroe, Rachel R., Madwed, Jeffrey, Moriak, Monica, Netherton, Matthew, Pargellis, Christopher A., Patel, Usha R., Qian, Kevin C., Sharma, Rajiv, Sun, Sanxing, Swinamer, Alan, Torcellini, Carol, Takahashi, Hidenori, Tsang, Michele, Xiong, Zhaoming
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Journal Article
Iron production and trading in Lingnan during the Qin and Han Dynasties
Zhang, Mengyi, Li, Yingfu, Xiong, Zhaoming, Li, Shijia, Li, Yuniu
Published in Antiquity (01.02.2020)
Published in Antiquity (01.02.2020)
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Journal Article
Evidences for the view of the importance of Hepu seaport in ancient China
Guan, Yongjing, Xiong, Zhaoming, Ruan, Xiangdong, Wang, Huijuan, Terrasi, Filippo
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01.01.2013)
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01.01.2013)
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Journal Article
Fragment-Based Discovery of Indole Inhibitors of Matrix Metalloproteinase-13
Taylor, Steven J, Abeywardane, Asitha, Liang, Shuang, Muegge, Ingo, Padyana, Anil K, Xiong, Zhaoming, Hill-Drzewi, Melissa, Farmer, Bennett, Li, Xiang, Collins, Brandon, Li, John Xiang, Heim-Riether, Alexander, Proudfoot, John, Zhang, Qiang, Goldberg, Daniel, Zuvela-Jelaska, Ljiljana, Zaher, Hani, Li, Jun, Farrow, Neil A
Published in Journal of medicinal chemistry (08.12.2011)
Published in Journal of medicinal chemistry (08.12.2011)
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Journal Article
Abstract ND06: ABBV-CLS-484: An active site PTPN2/N1 inhibitor that augments the immune response and sensitizes tumors to immune-mediated killing
Baumgartner, Christina K., Paddock, Marcia N., Frost, Jennifer M., Hamel, Keith M., McGuire, Kathleen A., Halliwill, Kyle, Xiong, Zhaoming, Mu, Liang, Klinge, Kelly, Geda, Prasanthi, Aguado, Jaqueline, Bulic, Marinka, Farney, Elliot P., Yates, Kathleen B., Manguso, Robert T., Beauregard, Clay, Kym, Philip R.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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