Prediction of pyrotinib exposure based on physiologically-based pharmacokinetic model and endogenous biomarker
Zhang, Miao, Yu, Zhiheng, Yao, Xueting, Lei, Zihan, Zhao, Kaijing, Wang, Wenqian, Zhang, Xue, Chen, Xijing, Liu, Dongyang
Published in Frontiers in pharmacology (23.09.2022)
Published in Frontiers in pharmacology (23.09.2022)
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Acute liver failure impairs function and expression of breast cancer‐resistant protein (BCRP) at rat blood–brain barrier partly via ammonia‐ROS‐ERK1/2 activation
Li, Ying, Zhang, Ji, Xu, Ping, Sun, Binbin, Zhong, Zeyu, Liu, Can, Ling, Zhaoli, Chen, Yang, Shu, Nan, Zhao, Kaijing, Liu, Li, Liu, Xiaodong
Published in Journal of neurochemistry (01.07.2016)
Published in Journal of neurochemistry (01.07.2016)
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Interspecies differences in metabolism of deoxypodophyllotoxin in hepatic microsomes from human, monkey, rat, mouse and dog
Xie, Qiushi, Chen, Yang, Liu, Fei, Zhong, Zeyu, Zhao, Kaijing, Ling, Zhaoli, Wang, Fan, Tang, Xiange, Wang, Zhongjian, Liu, Li, Liu, Xiaodong
Published in Drug metabolism and pharmacokinetics (01.08.2016)
Published in Drug metabolism and pharmacokinetics (01.08.2016)
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SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
Li, Ziming, Song, Zhengbo, Hong, Wei, Yang, Nong, Wang, Yongsheng, Jian, Hong, Liang, Zibin, Hu, Sheng, Peng, Min, Yu, Yan, Wang, Yan, Jiao, Zicong, Zhao, Kaijing, Song, Ke, Li, You, Shi, Wei, Lu, Shun
Published in Signal transduction and targeted therapy (15.07.2024)
Published in Signal transduction and targeted therapy (15.07.2024)
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Paroxetine decreased plasma exposure of glyburide partly via inhibiting intestinal absorption in rats
Jiang, Shuwen, Zhao, Weiman, Chen, Yang, Zhong, Zeyu, Zhang, Mian, Li, Feng, Xu, Ping, Zhao, Kaijing, Li, Ying, Liu, Li, Liu, Xiaodong
Published in Drug metabolism and pharmacokinetics (01.06.2015)
Published in Drug metabolism and pharmacokinetics (01.06.2015)
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Prediction of Deoxypodophyllotoxin Disposition in Mouse, Rat, Monkey, and Dog by Physiologically Based Pharmacokinetic Model and the Extrapolation to Human
Chen, Yang, Zhao, Kaijing, Liu, Fei, Xie, Qiushi, Zhong, Zeyu, Miao, Mingxing, Liu, Xiaodong, Liu, Li
Published in Frontiers in pharmacology (2016)
Published in Frontiers in pharmacology (2016)
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Prediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and Transporters
Wang, Zhongjian, Yang, Hanyu, Xu, Jiong, Zhao, Kaijing, Chen, Yang, Liang, Limin, Li, Ping, Chen, Nan, Geng, Donghao, Zhang, Xiangping, Liu, Xiaodong, Liu, Li
Published in Drug metabolism and disposition (01.10.2019)
Published in Drug metabolism and disposition (01.10.2019)
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Predicting Antitumor Effect of Deoxypodophyllotoxin in NCI-H460 Tumor-Bearing Mice on the Basis of In Vitro Pharmacodynamics and a Physiologically Based Pharmacokinetic-Pharmacodynamic Model
Chen, Yang, Zhao, Kaijing, Liu, Fei, Li, Ying, Zhong, Zeyu, Hong, Shijin, Liu, Xiaodong, Liu, Li
Published in Drug metabolism and disposition (01.06.2018)
Published in Drug metabolism and disposition (01.06.2018)
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Short-chain fatty acids oppositely altered expressions and functions of intestinal cytochrome P4503A and P-glycoprotein and affected pharmacokinetics of verapamil following oral administration to rats
Zhang, Jiaxin, Xie, Qiushi, Kong, Weimin, Wang, Zhongjian, Wang, Shuting, Zhao, Kaijing, Chen, Yang, Liu, Xiaodong, Liu, Li
Published in Journal of pharmacy and pharmacology (01.03.2020)
Published in Journal of pharmacy and pharmacology (01.03.2020)
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Impairment of Intestinal Monocarboxylate Transporter 6 Function and Expression in Diabetic Rats Induced by Combination of High-Fat Diet and Low Dose of Streptozocin: Involvement of Butyrate-Peroxisome Proliferator-Activated Receptor- γ Activation
Xu, Feng, Zhu, Liang, Qian, Chaoqun, Zhou, Junjie, Geng, Donghao, Li, Ping, Xuan, Wenjing, Wu, Fangge, Zhao, Kaijing, Kong, Weimin, Qin, Yuanyuan, Liang, Limin, Liu, Li, Liu, Xiaodong
Published in Drug metabolism and disposition (01.06.2019)
Published in Drug metabolism and disposition (01.06.2019)
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Safety, Efficacy, and Pharmacokinetics of SHR-A1811, a Human Epidermal Growth Factor Receptor 2-Directed Antibody-Drug Conjugate, in Human Epidermal Growth Factor Receptor 2-Expressing or Mutated Advanced Solid Tumors: A Global Phase I Trial
Yao, Herui, Yan, Min, Tong, Zhongsheng, Wu, Xinhong, Ryu, Min-Hee, Park, John J, Kim, Jee Hyun, Zhong, Yahua, Zhao, Yiming, Voskoboynik, Mark, Yin, Yongmei, Liu, Kan, Kaubisch, Andreas, Liu, Caigang, Zhang, Jian, Wang, Shouman, Im, Seock-Ah, Ganju, Vinod, Barve, Minal, Li, Hui, Ye, Changsheng, Roy, Amitesh C, Bai, Li-Yuan, Yen, Chia-Jui, Gu, Shanzhi, Lin, Yung-Chang, Wu, Lingying, Bao, Lequn, Zhao, Kaijing, Shen, Yu, Rong, Shangyi, Zhu, Xiaoyu, Song, Erwei
Published in Journal of clinical oncology (10.10.2024)
Published in Journal of clinical oncology (10.10.2024)
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Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes
Ling, Zhaoli, Shu, Nan, Xu, Ping, Wang, Fan, Zhong, Zeyu, Sun, Binbin, Li, Feng, Zhang, Mian, Zhao, Kaijing, Tang, Xiange, Wang, Zhongjian, Zhu, Liang, Liu, Li, Liu, Xiaodong
Published in Biochemical pharmacology (15.01.2016)
Published in Biochemical pharmacology (15.01.2016)
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Increase in P-glycoprotein levels in the blood-brain barrier of partial portal vein ligation /chronic hyperammonemia rats is medicated by ammonia/reactive oxygen species/ERK1/2 activation: In vitro and in vivo studies
Zhou, Yaqian, Zhou, Junjie, Li, Ping, Xie, Qiushi, Sun, Binbin, Li, Ying, Chen, Yang, Zhao, Kaijing, Yang, Tingting, Zhu, Liang, Xu, Jiong, Liu, Xiaodong, Liu, Li
Published in European journal of pharmacology (05.03.2019)
Published in European journal of pharmacology (05.03.2019)
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In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes
Tang, Xiange, Di, Xinyu, Zhong, Zeyu, Xie, Qiushi, Chen, Yang, Wang, Fan, Ling, Zhaoli, Xu, Ping, Zhao, Kaijing, Wang, Zhongjian, Liu, Li, Liu, Xiaodong
Published in Journal of pharmaceutical and biomedical analysis (05.09.2016)
Published in Journal of pharmaceutical and biomedical analysis (05.09.2016)
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Abstract CT204: Safety, tolerability, pharmacokinetics, and efficacy of SHR-A1811, an antibody-drug conjugate, in patients with advanced HER2 -mutant non-small cell lung cancer (NSCLC): a multicenter, open-label, phase 1/2 study
Lu, Shun, Jian, Hong, Hong, Wei, Song, Zhengbo, Yang, Nong, Hu, Sheng, Liang, Zibin, Wang, Yongsheng, Wang, Yan, Peng, Min, Yu, Yan, Li, You, Shuang, Jiapeng, Zhao, Kaijing
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
Acute liver failure impairs function and expression of breast cancer‐resistant protein ( BCRP ) at rat blood–brain barrier partly via ammonia‐ ROS ‐ ERK 1/2 activation
Li, Ying, Zhang, Ji, Xu, Ping, Sun, Binbin, Zhong, Zeyu, Liu, Can, Ling, Zhaoli, Chen, Yang, Shu, Nan, Zhao, Kaijing, Liu, Li, Liu, Xiaodong
Published in Journal of neurochemistry (01.07.2016)
Published in Journal of neurochemistry (01.07.2016)
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Abstract CT175: Safety, tolerability, pharmacokinetics, and antitumor activity of SHR-A1811 in HER2-expressing/mutated advanced solid tumors: A global phase 1, multi-center, first-in-human study
Yao, Herui, Yan, Min, Tong, Zhongsheng, Wu, Xinhong, Ryu, Min-Hee, Kim, Jee Hyun, Park, John, Zhong, Yahua, Han, Weiqing, Liu, Caigang, Voskoboynik, Mark, Qin, Qun, Zhang, Jian, Barve, Minal, Acuna-Villaorduna, Ana, Ganju, Vinod, Im, Seock-Ah, Ye, Changsheng, Yin, Yongmei, Roy, Amitesh C., Bai, Li-Yuan, Lin, Yung-Chang, Yen, Chia-Jui, Li, Hui, Chung, Ki Young, Gu, Shanzhi, Qian, Jun, Teng, Yuee, Chen, Yiding, Shen, Yu, Zhao, Kaijing, Rong, Shangyi, Zhu, Xiaoyu, Song, Erwei
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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