Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model
Zhao, Congke, Le, Xiangyang, Li, Mengqi, Hu, Yuanbo, Li, Xiaohui, Chen, Zhuo, Hu, Gaoyun, Hu, Liqing, Li, Qianbin
Published in Respiratory research (17.11.2023)
Published in Respiratory research (17.11.2023)
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Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway
Li, Lijun, Yin, Minghui, Hu, Liqing, Tian, Xiaoting, He, Xiangrong, Zhao, Congke, Li, Ying, Li, Qianbin, Li, Xiaohui
Published in Frontiers in pharmacology (01.10.2021)
Published in Frontiers in pharmacology (01.10.2021)
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Journal Article
Heat shock protein 110: A novel candidate for disease diagnosis and targeted therapy
Zhao, Congke, Xiang, Honglin, Li, Mengqi, Gao, Ruizhe, Zhang, Yifan, Li, Qianbin, Hu, Liqing
Published in Drug discovery today (01.12.2024)
Published in Drug discovery today (01.12.2024)
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Journal Article
Discovery and Optimization of Hsp110 and sGC Dual-Target Regulators for the Treatment of Pulmonary Arterial Hypertension
Hu, Yuanbo, Zhao, Congke, Tan, Wenhua, Li, Mengqi, Wang, Yu, Gao, Ruizhe, Chen, Zhuo, Jin, Zhenming, Hu, Liqing, Li, Qianbin
Published in Journal of medicinal chemistry (08.08.2024)
Published in Journal of medicinal chemistry (08.08.2024)
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Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension
Zhao, Congke, Wu, Yan, Li, Mengqi, Tan, Wenhua, Hu, Yuanbo, Wang, Yu, Gao, Ruizhe, Hu, Liqing, Li, Qianbin
Published in European journal of medicinal chemistry (05.12.2024)
Published in European journal of medicinal chemistry (05.12.2024)
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Design, synthesis and optimization of pyrazolo[3,4-b] pyridine derivatives as Hsp110-STAT3 interaction disruptors for the treatment of pulmonary arterial hypertension
Li, Mengqi, Zhao, Congke, Xiang, Honglin, Wang, Yu, Gao, Ruizhe, Cai, Qinling, Chen, Qingsong, Chen, Zhuo, Hu, Liqing, Li, Qianbin
Published in Bioorganic chemistry (01.12.2024)
Published in Bioorganic chemistry (01.12.2024)
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Journal Article
Design, synthesis and optimization of pyrazolo3,4-b pyridine derivatives as Hsp110-STAT3 interaction disruptors for the treatment of pulmonary arterial hypertension
Li, Mengqi, Zhao, Congke, Xiang, Honglin, Wang, Yu, Gao, Ruizhe, Cai, Qinling, Chen, Qingsong, Chen, Zhuo, Hu, Liqing, Li, Qianbin
Published in Bioorganic chemistry (14.10.2024)
Published in Bioorganic chemistry (14.10.2024)
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Identification of selective homeodomain interacting protein kinase 2 inhibitors, a potential treatment for renal fibrosis
Hu, Liqing, Wang, Guangying, Zhao, Congke, Peng, Zhangzhe, Tao, Lijian, Chen, Zhuo, Hu, Gaoyun, Li, Qianbin
Published in Bioorganic chemistry (01.09.2022)
Published in Bioorganic chemistry (01.09.2022)
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The association of arterial stiffness with estimated excretion levels of urinary sodium and potassium and their ratio in Chinese adults
Yang, Qinyu, Jiang, Weihong, He, Yongmei, Yang, Lin, Zhao, Congke, Li, Lijun, Yang, Pingting, Yin, Lu, Li, Xiaohui, Huang, Xin, Li, Ying
Published in Journal of human hypertension (01.04.2023)
Published in Journal of human hypertension (01.04.2023)
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TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats
Zhao, Congke, Hu, Liqing, He, Xiangrong, Li, Lijun, Yin, Minghui, Tettey, Abraham Terkpertey, Wang, Yu, Shen, Jingshan, Tang, Siyuan, Wu, Chunhui, Li, Qianbin, Wang, Zhen, Li, Xiaohui
Published in Vascular pharmacology (01.08.2022)
Published in Vascular pharmacology (01.08.2022)
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