Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation
Grace, Peter M., Strand, Keith A., Galer, Erika L., Urban, Daniel J., Wang, Xiaohui, Baratta, Michael V., Fabisiak, Timothy J., Anderson, Nathan D., Cheng, Kejun, Greene, Lisa I., Berkelhammer, Debra, Zhang, Yingning, Ellis, Amanda L., Yin, Hang Hubert, Campeau, Serge, Rice, Kenner C., Roth, Bryan L., Maier, Steven F., Watkins, Linda R.
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2016)
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DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats
Grace, Peter M., Wang, Xiaohui, Strand, Keith A., Baratta, Michael V., Zhang, Yingning, Galer, Erika L., Yin, Hang, Maier, Steven F., Watkins, Linda R.
Published in Experimental neurology (01.06.2018)
Published in Experimental neurology (01.06.2018)
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Structure–Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists
Selfridge, Brandon R, Wang, Xiaohui, Zhang, Yingning, Yin, Hang, Grace, Peter M, Watkins, Linda R, Jacobson, Arthur E, Rice, Kenner C
Published in Journal of medicinal chemistry (25.06.2015)
Published in Journal of medicinal chemistry (25.06.2015)
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Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain
Lewis, Susannah S, Hutchinson, Mark R, Zhang, Yingning, Hund, Dana K, Maier, Steven F, Rice, Kenner C, Watkins, Linda R
Published in Brain, behavior, and immunity (01.05.2013)
Published in Brain, behavior, and immunity (01.05.2013)
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Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1
Wang, Xiaohui, Fiorini, Zeno, Smith, Christina, Zhang, Yingning, Li, Jing, Watkins, Linda R, Yin, Hang
Published in PloS one (19.10.2012)
Published in PloS one (19.10.2012)
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The driving force for homeotropic alignment of a triphenylene derivative in a hexagonal columnar mesophase on single substrates
Wang, Junjie, He, Zhiqun, Zhang, Yingning, Zhao, Huan, Zhang, Chunxiu, Kong, Xiangfei, Mu, Linping, Liang, Chunjun
Published in Thin solid films (01.02.2010)
Published in Thin solid films (01.02.2010)
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Large-scale chemoenzymatic synthesis of blood group and tumor-associated poly- N-acetyllactosamine antigens
Vasiliu, Daniela, Razi, Nahid, Zhang, Yingning, Jacobsen, Nathan, Allin, Kirk, Liu, Xiaofei, Hoffmann, Julia, Bohorov, Ognian, Blixt, Ola
Published in Carbohydrate research (24.07.2006)
Published in Carbohydrate research (24.07.2006)
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Enhanced dielectric properties and improved thermal stability in TiO2-based ceramics by Cu and Nb co-doping
Qiao, Peng, Zhang, Yingning, Wang, Jing, Peng, Zhanhui, Wu, Di, Chao, Xiaolian, Yang, Zupei, Liang, Pengfei
Published in Ceramics international (01.01.2024)
Published in Ceramics international (01.01.2024)
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Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)
Hutchinson, Mark R., Zhang, Yingning, Brown, Kimberley, Coats, Benjamen D., Shridhar, Mitesh, Sholar, Paige W., Patel, Sonica J., Crysdale, Nicole Y., Harrison, Jacqueline A., Maier, Steven F., Rice, Kenner C., Watkins, Linda R.
Published in The European journal of neuroscience (01.07.2008)
Published in The European journal of neuroscience (01.07.2008)
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Evidence that opioids may have toll-like receptor 4 and MD-2 effects
Hutchinson, Mark R, Zhang, Yingning, Shridhar, Mitesh, Evans, John H, Buchanan, Madison M, Zhao, Tina X, Slivka, Peter F, Coats, Benjamen D, Rezvani, Niloofar, Wieseler, Julie, Hughes, Travis S, Landgraf, Kyle E, Chan, Stefanie, Fong, Stephanie, Phipps, Simon, Falke, Joseph J, Leinwand, Leslie A, Maier, Steven F, Yin, Hang, Rice, Kenner C, Watkins, Linda R
Published in Brain, behavior, and immunity (01.01.2010)
Published in Brain, behavior, and immunity (01.01.2010)
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Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1β
Lewis, S.S, Hutchinson, M.R, Rezvani, N, Loram, L.C, Zhang, Y, Maier, S.F, Rice, K.C, Watkins, L.R
Published in Neuroscience (20.01.2010)
Published in Neuroscience (20.01.2010)
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Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia
Hutchinson, Mark R, Coats, Benjamen D, Lewis, Susannah S, Zhang, Yingning, Sprunger, David B, Rezvani, Niloofar, Baker, Eric M, Jekich, Brian M, Wieseler, Julie L, Somogyi, Andrew A, Martin, David, Poole, Stephen, Judd, Charles M, Maier, Steven F, Watkins, Linda R
Published in Brain, behavior, and immunity (01.11.2008)
Published in Brain, behavior, and immunity (01.11.2008)
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(+)-Naloxone, an Opioid-Inactive Toll-Like Receptor 4 Signaling Inhibitor, Reverses Multiple Models of Chronic Neuropathic Pain in Rats
Lewis, Susannah S, Loram, Lisa C, Hutchinson, Mark R, Li, Chien-Ming, Zhang, Yingning, Maier, Steven F, Huang, Yong, Rice, Kenner C, Watkins, Linda R
Published in The journal of pain (01.05.2012)
Published in The journal of pain (01.05.2012)
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Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia
Hutchinson, Mark R, Northcutt, Alexis L, Chao, Lindsey W, Kearney, Jeffrey J, Zhang, Yingning, Berkelhammer, Debra L, Loram, Lisa C, Rozeske, Robert R, Bland, Sondra T, Maier, Steven F, Gleeson, Todd T, Watkins, Linda R
Published in Brain, behavior, and immunity (01.11.2008)
Published in Brain, behavior, and immunity (01.11.2008)
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Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain
Lewis, Susannah S, Hutchinson, Mark R, Frick, Morin M, Zhang, Yingning, Maier, Steven F, Sammakia, Tarek, Rice, Kenner C, Watkins, Linda R
Published in Brain, behavior, and immunity (01.02.2015)
Published in Brain, behavior, and immunity (01.02.2015)
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A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4
Bastos, Leandro F.S., Godin, Adriana M., Zhang, Yingning, Jarussophon, Suwatchai, Ferreira, Bruno C.S., Machado, Renes R., Maier, Steven F., Konishi, Yasuo, de Freitas, Rossimiriam P., Fiebich, Bernd L., Watkins, Linda R., Coelho, Márcio M., Moraes, Márcio F.D.
Published in Neuroscience letters (24.05.2013)
Published in Neuroscience letters (24.05.2013)
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Evidence that tricyclic small molecules may possess Toll-like receptor and MD-2 activity
Hutchinson, Mark R., Loram, Lisa C., Zhang, Yingning, Shridhar, Mitesh, Rezvani, Niloofar, Berkelhammer, Debra, Phipps, Simon, Foster, Paul S., Landgraf, Kyle, Falke, Joseph J., Rice, Kenner C., Maier, Steven F., Yin, Hang, Watkins, Linda R.
Published in Neuroscience (08.04.2010)
Published in Neuroscience (08.04.2010)
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Possible involvement of Toll-Like Receptor 4/MD-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences
Hutchinson, Mark R., Lewis, Susannah S., Coats, Benjamen D., Rezvani, Niloofar, Zhang, Yingning, Wieseler, Julie L., Somogyi, Andrew A., Yin, Hang, Maier, Steven F., Rice, Kenner C., Watkins, Linda R.
Published in Neuroscience (21.02.2010)
Published in Neuroscience (21.02.2010)
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Evidence for a role of heat shock protein-90 (HSP90) in TLR4 mediated pain enhancement in rats
Hutchinson, Mark R., Ramos, Khara M., Loram, Lisa C., Wieseler, Julie, Sholar, Paige W., Kearney, Jeffrey J., Lewis, Makenzie T., Crysdale, Nicole Y., Zhang, Yingning, Harrison, Jacqueline A., Maier, Steven F., Rice, Kenner C., Watkins, Linda R.
Published in Neuroscience (27.09.2009)
Published in Neuroscience (27.09.2009)
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