Targeting amyloid proteins for clinical diagnosis of neurodegenerative diseases
Zhang, Shenqing, Dong, Hui, Bian, Jiang, Li, Dan, Liu, Cong
Published in Fundamental research (Beijing) (01.07.2023)
Published in Fundamental research (Beijing) (01.07.2023)
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Journal Article
Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation
Li, Yichen, Gu, Jinge, Wang, Chen, Hu, Jiaojiao, Zhang, Shenqing, Liu, Cong, Zhang, Shengnan, Fang, Yanshan, Li, Dan
Published in iScience (17.06.2022)
Published in iScience (17.06.2022)
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Journal Article
Molecular structure of an amyloid fibril formed by FUS low-complexity domain
Sun, Yunpeng, Zhang, Shenqing, Hu, Jiaojiao, Tao, Youqi, Xia, Wencheng, Gu, Jinge, Li, Yichen, Cao, Qin, Li, Dan, Liu, Cong
Published in iScience (21.01.2022)
Published in iScience (21.01.2022)
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Ultrasensitive detection of aggregated α-synuclein using quiescent seed amplification assay for the diagnosis of Parkinson's disease
Mao, Hengxu, Kuang, Yaoyun, Feng, Du, Chen, Xiang, Lu, Lin, Xia, Wencheng, Gan, Tingting, Huang, Weimeng, Guo, Wenyuan, Yi, Hancun, Yang, Yirong, Wu, Zhuohua, Dai, Wei, Sun, Hui, Wu, Jieyuan, Zhang, Rui, Zhang, Shenqing, Lin, Xiuli, Yong, Yuxuan, Yang, Xinling, Li, Hongyan, Wu, Wenjun, Huang, Xiaoyun, Bian, Zhaoxiang, Wong, Hoi Leong Xavier, Wang, Xin-Lu, Poppell, Michael, Ren, Yi, Liu, Cong, Zou, Wen-Quan, Chen, Shengdi, Xu, Ping-Yi
Published in Translational neurodegeneration (24.07.2024)
Published in Translational neurodegeneration (24.07.2024)
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Journal Article
Chemical probes for investigating protein liquid-liquid phase separation and aggregation
Sun, Rui, Zhang, Shenqing, Liu, Yu, Li, Dan
Published in Current opinion in chemical biology (01.06.2023)
Published in Current opinion in chemical biology (01.06.2023)
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Journal Article
Global profiling of arginine dimethylation in regulating protein phase separation by a steric effect-based chemical-enrichment method
Wang, Qi, Li, Zhouxian, Zhang, Shenqing, Li, Yichen, Wang, Yan, Fang, Zheng, Ma, Yanni, Liu, Zhen, Zhang, Weibing, Li, Dan, Liu, Cong, Ye, Mingliang
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2022)
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Journal Article
Nucleocapsid proteins from human coronaviruses possess phase separation capabilities and promote FUS pathological aggregation
Dong, Hui, Zhang, Hong, Jalin, Julie, He, Ziqi, Wang, Runhan, Huang, Leqi, Liu, Zibo, Zhang, Shenqing, Dai, Bin, Li, Dan
Published in Protein science (01.12.2023)
Published in Protein science (01.12.2023)
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Journal Article
Structural mechanism for specific binding of chemical compounds to amyloid fibrils
Tao, Youqi, Xia, Wencheng, Zhao, Qinyue, Xiang, Huaijiang, Han, Chao, Zhang, Shenqing, Gu, Wei, Tang, Wenjun, Li, Ying, Tan, Li, Li, Dan, Liu, Cong
Published in Nature chemical biology (01.10.2023)
Published in Nature chemical biology (01.10.2023)
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Journal Article
Time-course remodeling and pathology intervention of α-synuclein amyloid fibril by heparin and heparin-like oligosaccharides
Tao, Youqi, Xu, Peng, Zhang, Shenqing, Shangguan, Wei, Yang, Guang, Liu, Kaien, Li, Xiang, Sun, Yunpeng, Zhao, Qinyue, Li, Dan, Yu, Biao, Liu, Cong
Published in Nature structural & molecular biology (17.10.2024)
Published in Nature structural & molecular biology (17.10.2024)
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Journal Article
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils
Liu, Kaien, Tao, Youqi, Zhao, Qinyue, Xia, Wencheng, Li, Xiang, Zhang, Shenqing, Yao, Yuxuan, Xiang, Huaijiang, Han, Chao, Tan, Li, Sun, Bo, Li, Dan, Li, Ang, Liu, Cong
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2024)
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Journal Article
Generic amyloid fibrillation of TMEM106B in patient with Parkinson’s disease dementia and normal elders
Fan, Yun, Zhao, Qinyue, Xia, Wencheng, Tao, Youqi, Yu, Wenbo, Chen, Mingjia, Liu, Yiqi, Zhao, Jue, Shen, Yan, Sun, Yunpeng, Si, Chenfang, Zhang, Shenqing, Zhang, Yaoyang, Li, Wensheng, Liu, Cong, Wang, Jian, Li, Dan
Published in Cell research (01.06.2022)
Published in Cell research (01.06.2022)
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Journal Article
Inhibitor Development for α‑Synuclein Fibril’s Disordered Region to Alleviate Parkinson’s Disease Pathology
Zhang, Shenqing, Xiang, Huaijiang, Tao, Youqi, Li, Juan, Zeng, Shuyi, Xu, Qianhui, Xiao, Haonan, Lv, Shiran, Song, Caiwei, Cheng, Yan, Li, Martin, Zhu, Zeyun, Zhang, Shengnan, Sun, Bo, Li, Dan, Xiang, ShengQi, Tan, Li, Liu, Cong
Published in Journal of the American Chemical Society (27.09.2024)
Published in Journal of the American Chemical Society (27.09.2024)
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Journal Article
Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure
Li, Xiang, Zhang, Shenqing, Liu, Zhengtao, Tao, Youqi, Xia, Wencheng, Sun, Yunpeng, Liu, Cong, Le, Weidong, Sun, Bo, Li, Dan
Published in iScience (22.12.2022)
Published in iScience (22.12.2022)
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Journal Article
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation
Li, Yichen, Lu, Shuaiyao, Gu, Jinge, Xia, Wencheng, Zhang, Shengnan, Zhang, Shenqing, Wang, Yan, Zhang, Chong, Sun, Yunpeng, Lei, Jian, Liu, Cong, Su, Zhaoming, Yang, Juntao, Peng, Xiaozhong, Li, Dan
Published in Protein & cell (01.08.2022)
Published in Protein & cell (01.08.2022)
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Journal Article
Self-limiting multimerization of α-synuclein on membrane and its implication in Parkinson's diseases
Ma, Dong-Fei, Zhang, Shenqing, Xu, Si-Yao, Huang, Zi, Tao, Yuanxiao, Chen, Feiyang, Zhang, Shengnan, Li, Dan, Chen, Tongsheng, Liu, Cong, Li, Ming, Lu, Ying
Published in Science advances (11.10.2024)
Published in Science advances (11.10.2024)
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