A replicate designed bioequivalence study to compare two fixed-dose combination products of artesunate and amodiaquine in healthy chinese volunteers
Liu, Yun, Hu, Chaoying, Liu, Gangyi, Jia, Jingying, Yu, Chen, Zhu, Jianmin, Zheng, Qingsi, Zhang, Kanyin E
Published in Antimicrobial agents and chemotherapy (01.10.2014)
Published in Antimicrobial agents and chemotherapy (01.10.2014)
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Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2
Jiang, Tao, Kuhen, Kelli L., Wolff, Karen, Yin, Hong, Bieza, Kimberly, Caldwell, Jeremy, Bursulaya, Badry, Tuntland, Tove, Zhang, Kanyin, Karanewsky, Donald, He, Yun
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Bioequivalence and Safety of Levetiracetam Granules and Oral Solution: A Randomized, Single‐Dose, 2‐Period Crossover Study in Healthy Chinese Volunteers Under a Fasting Condition
Liu, Yun, Zou, Yang, Wang, Yijun, Jiang, Fan, Xu, Wenjing, Liu, Shuyun, Jia, Jingying, Yu, Chen, Fang, Liming, Hu, Liwei, Zhang, Kanyin E., Long, Jingwen, Pu, Huahua
Published in Clinical pharmacology in drug development (01.03.2022)
Published in Clinical pharmacology in drug development (01.03.2022)
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Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions
Wu, Qingqing, Wang, Xiaodong, Chen, Qian, Zou, Yang, Xu, Xiaoyan, Li, Tingting, Yu, Chen, Zhu, Fu, Zhang, Kanyin E, Jia, Jingying, Liu, Yanmei
Published in Drug design, development and therapy (01.01.2020)
Published in Drug design, development and therapy (01.01.2020)
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Pharmacokinetic Properties and Bioequivalence of Two Sulfadoxine/Pyrimethamine Fixed-Dose Combination Tablets: A Parallel-Design Study in Healthy Chinese Male Volunteers
Liu, Yan-Mei, MD, Zhang, Kanyin E., PhD, Liu, Yun, MD, Zhang, Hai-Chen, MD, Song, Yun-Xiao, MD, Pu, Hua-Hua, MD, Lu, Chuan, BS, Liu, Gang-Yi, MS, Jia, Jing-Ying, MS, Zheng, Qing-Si, MS, Zhu, Jian-Min, MD, Yu, Chen, MS
Published in Clinical therapeutics (01.11.2012)
Published in Clinical therapeutics (01.11.2012)
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Circulating Metabolites of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir in Humans: Structural Identification, Levels in Plasma, and Antiviral Activities
ZHANG, Kanyin E, WU, Ellen, PATICK, Amy K, KERR, Bradley, ZORBAS, Mark, LANKFORD, Angela, KOBAYASHI, Takuo, MAEDA, Yuki, SHETTY, Bhasker, WEBBER, Stephanie
Published in Antimicrobial Agents and Chemotherapy (01.04.2001)
Published in Antimicrobial Agents and Chemotherapy (01.04.2001)
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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure
Canan Koch, Stacie S, Thoresen, Lars H, Tikhe, Jayashree G, Maegley, Karen A, Almassy, Robert J, Li, Jianke, Yu, Xiao-Hong, Zook, Scott E, Kumpf, Robert A, Zhang, Cathy, Boritzki, Theodore J, Mansour, Rena N, Zhang, Kanyin E, Ekker, Anne, Calabrese, Chris R, Curtin, Nicola J, Kyle, Suzanne, Thomas, Huw D, Wang, Lan-Zhen, Calvert, A. Hilary, Golding, Bernard T, Griffin, Roger J, Newell, David R, Webber, Stephen E, Hostomsky, Zdenek
Published in Journal of medicinal chemistry (07.11.2002)
Published in Journal of medicinal chemistry (07.11.2002)
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METABOLISM AND DISPOSITION OF A POTENT GROUP II METABOTROPIC GLUTAMATE RECEPTOR AGONIST, IN RATS, DOGS, AND MONKEYS
JAMES, Joyce K, NAKAMURA, Masato, NAKAZATO, Atsuro, ZHANG, Kanyin E, CRAMER, Merryl, BRUNNER, Janice, COOK, Jacquelynn, CHEN, Weichao G
Published in Drug metabolism and disposition (01.09.2005)
Published in Drug metabolism and disposition (01.09.2005)
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Liquid Chromatography-Mass Spectrometry and Liquid Chromatography-NMR Characterization of in Vitro Metabolites of a Potent and Irreversible Peptidomimetic Inhibitor of Rhinovirus 3C Protease
ZHANG, Kanyin E, HEE, Brian, LEE, Caroline A, BAIHONG LIANG, POTTS, Barbara C. M
Published in Drug metabolism and disposition (01.05.2001)
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Published in Drug metabolism and disposition (01.05.2001)
Journal Article
The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
HALPIN, Rita A, GEER, Leslie A, ZHANG, Kanyin E, MARKS, Tina M, DEAN, Dennis C, JONES, Allen N, MELILLO, David, DOSS, George, VYAS, Kamlesh P
Published in Drug metabolism and disposition (01.10.2000)
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Published in Drug metabolism and disposition (01.10.2000)
Journal Article
Microsomal Metabolism of the 5-Lipoxygenase Inhibitor L-739,010: Evidence for Furan Bioactivation
Zhang, Kanyin E, Naue, Jeanne A, Arison, Byron, Vyas, Kamlesh P
Published in Chemical research in toxicology (01.03.1996)
Published in Chemical research in toxicology (01.03.1996)
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Circulating Metabolites of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir in Humans: Structural Identification, Levels in Plasma, and Antiviral Activities
Zhang, Kanyin E, Wu, Ellen, Patick, Amy K, Kerr, Bradley, Zorbas, Mark, Lankford, Angela, Kobayashi, Takuo, Maeda, Yuki, Shetty, Bhasker, Webber, Stephanie
Published in Antimicrobial agents and chemotherapy (01.08.2001)
Published in Antimicrobial agents and chemotherapy (01.08.2001)
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Evaluation of intraocular pharmacokinetics and toxicity of prinomastat (AG3340) in the rabbit
Cheng, L, Rivero, M E, Garcia, C R, McDermott, C D, Keefe, K S, Wiley, C A, Soules, K A, Bergeron-Lynn, G, Vekich, S, Zhang, K, Appelt, K, Freeman, W R
Published in Journal of ocular pharmacology and therapeutics (01.06.2001)
Published in Journal of ocular pharmacology and therapeutics (01.06.2001)
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Metabolism of A Dopamine D4-Selective Antagonist in Rat, Monkey, and Humans: Formation of A Novel Mercapturic Acid Adduct
Kanyin E. Zhang, Prasad H. Kari, Margaret R. Davis, George Doss, Thomas A. Baillie, Kamlesh P. Vyas
Published in Drug metabolism and disposition (01.06.2000)
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Published in Drug metabolism and disposition (01.06.2000)
Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 3. Approaches To Eliminate Opioid Agonist Metabolites by Using Substituted Phenylpiperazine Side Chains
Lagu, Bharat, Tian, Dake, Nagarathnam, Dhanapalan, Marzabadi, Mohammad R, Wong, Wai C, Miao, Shou W, Zhang, Fengqi, Sun, Wanying, Chiu, George, Fang, James, Forray, Carlos, Chang, Raymond S. L, Ransom, Richard W, Chen, Tsing B, O'Malley, Stacey, Zhang, Kanyin, Vyas, Kamlesh P, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 4. Structure−Activity Relationship in the Dihydropyrimidine Series
Wong, Wai C, Sun, Wanying, Lagu, Bharat, Tian, Dake, Marzabadi, Mohammad R, Zhang, Fengqi, Nagarathnam, Dhanapalan, Miao, Shou W, Wetzel, John M, Peng, Jian, Forray, Carlos, Chang, Raymond S. L, Chen, Tsing B, Ransom, Richard, O'Malley, Stacey, Broten, Theodore P, Kling, Paul, Vyas, Kamlesh P, Zhang, Kanyin, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety
Murali Dhar, T. G, Nagarathnam, Dhanapalan, Marzabadi, Mohammad R, Lagu, Bharat, Wong, Wai C, Chiu, George, Tyagarajan, Sriram, Miao, Shou Wu, Zhang, Fengqi, Sun, Wanying, Tian, Dake, Shen, Quanrong, Zhang, Jack, Wetzel, John M, Forray, Carlos, Chang, Raymond S. L, Broten, Theodore P, Schorn, Terry W, Chen, Tsing Bao, O'Malley, Stacy, Ransom, Richard, Schneck, Kathryn, Bendesky, Robert, Harrell, Charles M, Vyas, Kamlesh P, Zhang, Kanyin, Gilbert, John, Pettibone, Douglas J, Patane, Michael A, Bock, Mark G, Freidinger, Roger M, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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In vitro and in vivo investigations of dihydropyridine-based chemical delivery systems for anticonvulsants
Boddy, A V, Zhang, K, Lepage, F, Tombret, F, Slatter, J G, Baillie, T A, Levy, R H
Published in Pharmaceutical research (01.06.1991)
Published in Pharmaceutical research (01.06.1991)
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