Involvement of normalized NMDA receptor and mTOR-related signaling in rapid antidepressant effects of Yueju and ketamine on chronically stressed mice
Tang, Juanjuan, Xue, Wenda, Xia, Baomei, Ren, Li, Tao, Weiwei, Chen, Chang, Zhang, Hailou, Wu, Ruyan, Wang, Qisheng, Wu, Haoxin, Duan, Jinao, Chen, Gang
Published in Scientific reports (28.08.2015)
Published in Scientific reports (28.08.2015)
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Chronic stress prior to pregnancy potentiated long-lasting postpartum depressive-like behavior, regulated by Akt-mTOR signaling in the hippocampus
Xia, Baomei, Chen, Chang, Zhang, Hailou, Xue, Wenda, Tang, Juanjuan, Tao, Weiwei, Wu, Ruyan, Ren, Li, Wang, Wei, Chen, Gang
Published in Scientific reports (19.10.2016)
Published in Scientific reports (19.10.2016)
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Optimization of supercritical fluid extraction of oil from the fruit of Gardenia jasminoides and its antidepressant activity
Tao, Weiwei, Zhang, Hailou, Xue, Wenda, Ren, Li, Xia, Baomei, Zhou, Xin, Wu, Haoxin, Duan, Jinao, Chen, Gang
Published in Molecules (Basel, Switzerland) (25.11.2014)
Published in Molecules (Basel, Switzerland) (25.11.2014)
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The Rapid and Long-Lasting Antidepressant Effects of Iridoid Fraction in Gardenia Jasminoides J.Ellis Are Dependent on Activating PKA-CREB Signaling Pathway
Ren, Li, Zhang, Hailou, Tao, Weiwei, Chen, Yin, Zou, Zhilu, Guo, XiaoYan, Shen, Qinqin, Feng, Quansheng, Hu, Jingqing
Published in Frontiers in pharmacology (08.06.2022)
Published in Frontiers in pharmacology (08.06.2022)
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Jianpi Jieyu Decoction, An Empirical Herbal Formula, Exerts Psychotropic Effects in Association With Modulation of Gut Microbial Diversity and GABA Activity
Liu, Lanying, Zou, Zhilu, Yang, Jiangwei, Li, Xiaoqi, Zhu, Boran, Zhang, Hailou, Sun, Yan, Zhang, Yuxuan, Zhang, Zhang-Jin, Wang, Wei
Published in Frontiers in pharmacology (14.04.2021)
Published in Frontiers in pharmacology (14.04.2021)
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ZeXieYin formula alleviates atherosclerosis by inhibiting the MAPK/NF-κB signaling pathway in APOE−/− mice to attenuate vascular inflammation and increase plaque stability
Huang, Rumin, Sun, Yan, Liu, Ruiyi, Zhu, Boran, Zhang, Hailou, Wu, Haoxin
Published in Journal of ethnopharmacology (12.06.2024)
Published in Journal of ethnopharmacology (12.06.2024)
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Jiawei-Xiaoyao pill elicits a rapid antidepressant effect, dependent on activating CaMKII/mTOR/BDNF signaling pathway in the hippocampus
Zhang, Hailou, Sun, Yan, Huang, Zihao, Wu, Zhangjie, Ying, Yin, Liu, Ruiyi, Lin, Juan, Li, Chuyuan, Chen, Gang
Published in Journal of ethnopharmacology (10.01.2024)
Published in Journal of ethnopharmacology (10.01.2024)
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Zexieyin formula alleviates Alzheimer's disease via post-synaptic CaMKII modulating AMPA receptor: Involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus
Sun, Yan, Zhang, Hailou, Liu, Ruiyi, Wang, Yanqing, Zhang, Xiangrui, Huang, Rumin, Zhu, Boran, Wu, Haoxin
Published in Phytomedicine (Stuttgart) (01.08.2024)
Published in Phytomedicine (Stuttgart) (01.08.2024)
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PKA-CREB-BDNF signaling regulated long lasting antidepressant activities of Yueju but not ketamine
Xue, Wenda, Wang, Wei, Gong, Tong, Zhang, Hailou, Tao, Weiwei, Xue, Lihong, Sun, Yan, Wang, Fushun, Chen, Gang
Published in Scientific reports (20.05.2016)
Published in Scientific reports (20.05.2016)
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Pyrolae herba alleviates cognitive impairment via hippocampal TREM2 signaling modulating neuroinflammation and neurogenesis in lipopolysaccharide-treated mice
Sun, Yan, Zhang, Hailou, Liu, Ruiyu, Huang, Rumin, Zhang, Xiangrui, Zhou, Shihan, Wu, Lei, Zhu, Boran, Wu, Haoxin
Published in Journal of ethnopharmacology (30.01.2024)
Published in Journal of ethnopharmacology (30.01.2024)
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Zexieyin formula alleviates atherosclerosis with cognitive impairment: A novel role in the treatment of comorbidities and its underlying mechanisms
Sun, Yan, Zhang, Hailou, Liu, Ruiyi, Xing, Shan, Huang, Rumin, Di, Dong, Zhang, Xiyuan, Zhu, Boran, Wu, Haoxin
Published in Journal of ethnopharmacology (06.04.2024)
Published in Journal of ethnopharmacology (06.04.2024)
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Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus
Sun, Yan, Zhang, Hailou, Wu, Zhangjie, Yu, Xinlang, Yin, Ying, Qian, Shiyu, Wang, Ziying, Huang, Jiaru, Wang, Wei, Liu, Tao, Xue, Wenda, Chen, Gang
Published in ACS chemical neuroscience (15.09.2021)
Published in ACS chemical neuroscience (15.09.2021)
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Lancao decoction alleviates cognitive dysfunction: A new therapeutic drug and its therapeutic mechanism
Sun, Yan, Zhang, Hailou, Liu, Ruiyi, Huang, Rumin, Gao, Ziwei, Tian, Liyuan, Zhu, Yaping, Liu, Yuxin, Lu, Chao, Wu, Lei
Published in Phytomedicine (Stuttgart) (01.06.2024)
Published in Phytomedicine (Stuttgart) (01.06.2024)
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A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling
Wu, Zhangjie, Yin, Ying, Liu, Ruiyi, Li, Xianhui, Sun, Yan, Yau, Suk-yu, Wu, Lei, Liu, Yan, Adzic, Miroslav, Zhang, Hailou, Chen, Gang
Published in Journal of ethnopharmacology (05.12.2024)
Published in Journal of ethnopharmacology (05.12.2024)
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Lancao decoction in the treatment of alzheimer's disease via activating PI3K/AKT signaling to promote ERK involving in enhancing neuronal activities in the hippocampus
Wu, Lei, Sun, Yan, Yin, Ying, Wu, Zhangjie, Liu, Ruiyi, Liu, Yuxin, Zhu, Yaping, Shao, Mengqi, Zhou, Hang, Lu, Chao, Zhang, Hailou
Published in Journal of ethnopharmacology (01.11.2024)
Published in Journal of ethnopharmacology (01.11.2024)
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Synergistic effects of two naturally occurring iridoids in eliciting a rapid antidepressant action by up‐regulating hippocampal PACAP signalling
Zhang, Hailou, Sun, Yan, Yau, Suk‐yu, Zhou, Yanmeng, Song, Xinxin, Zhang, Han‐Ting, Zhu, Boran, Wu, Haoxin, Chen, Gang
Published in British journal of pharmacology (01.08.2022)
Published in British journal of pharmacology (01.08.2022)
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Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling
Zhang, Hailou, Sun, Yan, Qian, Shiyu, Ge, Rui, Guo, Xiaoyan, Shen, Qinqin, Sheng, Li, Nie, Chunying, Zhang, Yi, Yao, Yao, Zhou, Tong, Wang, Wei, Xue, Wenda, Chen, Gang
Published in Journal of ethnopharmacology (25.03.2020)
Published in Journal of ethnopharmacology (25.03.2020)
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Transgenerational impairment of hippocampal Akt-mTOR signaling and behavioral deficits in the offspring of mice that experience postpartum depression-like illness
Wu, Ruyan, Zhang, Hailou, Xue, Wenda, Zou, Zhilu, Lu, Cai, Xia, Baomei, Wang, Wei, Chen, Gang
Published in Progress in neuro-psychopharmacology & biological psychiatry (06.02.2017)
Published in Progress in neuro-psychopharmacology & biological psychiatry (06.02.2017)
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Hippocampal pituitary adenylate cyclase–activating polypeptide mediates rapid antidepressant-like effects of Yueju pill
Ren, Li, Zhang, Hailou, Tao, Weiwei, Xue, Wenda, Chen, Yin, Zou, Zhilu, Guo, Xiaoyan, Shen, Qinqin, Wang, Wei, Jiang, Haitang, Tang, Juanjuan, Feng, Quansheng, Chen, Gang
Published in Neuropeptides (Edinburgh) (01.10.2023)
Published in Neuropeptides (Edinburgh) (01.10.2023)
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Chronic treatment of mixture of two iridoids proportional to prescriptional dose of Yueju improves hippocampal PACAP-related neuroinflammation and neuroplasticity signaling in the LPS-induced depression model
Wu, Zhangjie, Yin, Ying, Liu, Ruiyi, Li, Xianhui, Wang, Ziying, Wu, Changyu, Tan, Jingwen, Fu, Zhenzhen, Song, Chenghao, Lee Wong, Nga, Peng, Xiangyi, Lai, Shixiong, Cui, Jinshuai, Han, Mingzhi, Peng, Yuhan, Sun, Yan, Wu, Lei, Adzic, Miroslav, Zeng, Li, Zhang, Hailou, Yau, Suk-yu, Chen, Gang
Published in Journal of ethnopharmacology (01.11.2024)
Published in Journal of ethnopharmacology (01.11.2024)
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