Abundant anti‐apoptotic BCL‐2 is a molecular target in leukaemias with t(4;11) translocation
Robinson, Blaine W., Behling, Kathryn C., Gupta, Manish, Zhang, Alena Y., Moore, Jonni S., Bantly, Andrew D., Willman, Cheryl L., Carroll, Andrew J., Adamson, Peter C., Barrett, Jeffrey S., Felix, Carolyn A.
Published in British journal of haematology (01.06.2008)
Published in British journal of haematology (01.06.2008)
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Journal Article
Predicting Clinical Dose-Exposure and Exposure-Response Relationships of Pan-Antiapoptotic BCL-2 Family Inhibitor Obatoclax in MLL Rearranged Infant Leukemias From Preclinical Disease Models and Adult Experience
Barrett, Jeffrey S, Zhang, Alena Y., Urtishak, Karen A., Danet-Desnoyers, Gwenn, Carroll, Andrew J., Hunger, Stephen P., Felix, Carolyn A.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Infant Acute Lymphoblastic Leukemias Are Pan-Sensitive to Obatoclax Across molecular/Cytogenetic Subtypes, Especially MLL-ENL, and gene Expression Profiles Determine Obatoclax IC50: A Report on the Children's Oncology Group (COG) P9407 Trial
Urtishak, Karen A., Wang, Li-San, Harvey, Richard, Atlas, Susan R, Chen, I-Ming L., Robinson, Blaine W., Moukarzel, Lea, Cao, Kajia, Devidas, Meenakshi, Carroll, Andrew J., Heerema, Nyla A., Hunger, Stephen, Reaman, Gregory H., Hilden, Joanne M., Camitta, Bruce, Winick, Naomi, Carroll, William L., Zhang, Alena Y., Cory, Lori, Mc Veigh, Steven, Barrett, Jeffery S., Dreyer, Zoann E., Willman, Cheryl L., Felix, Carolyn A.
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Cell Death Regulatory Gene Expression Correlates with MLL Rearrangement Status and Prognostic Clinical Covariates in Acute Leukemia in Infants
Zhang, Alena Y., Robinson, Blaine W., Kao, Kajia, Behling, Kathryn, Devidas, Meenakshi, Alonzo, Todd, Raimondi, Susana C., Carroll, Andrew, Arceci, Robert J., Gamis, Alan, Hunger, Stephen P., Reaman, Gregory H., Harvey, Richard C., Willman, Cheryl L., Wang, Li-San, Felix, Carolyn A.
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
Pan-Anti-Apoptotic BCL-2 Family Inhibitor, Obatoclax, Activates Autophagic Cell Death Pathway and Has Potent Cytotoxicity in Infant and Pediatric MLL-Rearranged Leukemias
Zhang, Alena Y., Robinson, Blaine W., Wang, Li-San, Kao, Kajia, Cory, Lori, Barrett, Jeffrey S., Atlas, Susan, Chen, I-Ming, Harvey, Richard C., Willman, Cheryl L., Devidas, Meenakshi, Carroll, Andrew J., Hunger, Stephen P., Moore, Jonni S., Thompson, Craig B., Kundu, Mondira, Felix, Carolyn A.
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article