Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
Li, Zhe, Li, Xin, Huang, Yi-You, Wu, Yaoxing, Liu, Runduo, Zhou, Lingli, Lin, Yuxi, Wu, Deyan, Zhang, Lei, Liu, Hao, Xu, Ximing, Yu, Kunqian, Zhang, Yuxia, Cui, Jun, Zhan, Chang-Guo, Wang, Xin, Luo, Hai-Bin
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)
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Journal Article
Cocaine hydrolase blocks cocaine‐induced dopamine transporter trafficking to the plasma membrane
Deng, Jing, Kim, Kyungbo, Zheng, Xirong, Shang, Linyue, Zhan, Chang‐Guo, Zheng, Fang
Published in Addiction biology (01.01.2022)
Published in Addiction biology (01.01.2022)
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Journal Article
Human Butyrylcholinesterase Mutants for (−)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole
Zheng, Fang, Hou, Shurong, Xue, Liu, Yang, Wenchao, Zhan, Chang-Guo
Published in The journal of physical chemistry. B (21.12.2023)
Published in The journal of physical chemistry. B (21.12.2023)
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Journal Article
Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine
Zhan, Max, Hou, Shurong, Shang, Linyue, Chen, Xiabin, Zhan, Chang-Guo, Zheng, Fang
Published in Organic & biomolecular chemistry (03.05.2023)
Published in Organic & biomolecular chemistry (03.05.2023)
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Journal Article
Recovery of dopaminergic system after cocaine exposure and impact of a long‐acting cocaine hydrolase
Deng, Jing, Zhang, Ting, Zheng, Xirong, Shang, Linyue, Zhan, Chang‐Guo, Zheng, Fang
Published in Addiction biology (01.07.2022)
Published in Addiction biology (01.07.2022)
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Journal Article
The role of human dopamine transporter in NeuroAIDS
Zhu, Jun, Ananthan, Subramaniam, Zhan, Chang-Guo
Published in Pharmacology & therapeutics (Oxford) (01.03.2018)
Published in Pharmacology & therapeutics (Oxford) (01.03.2018)
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Journal Article
Multiobjective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex
Feng, Hongsong, Wang, Rui, Zhan, Chang-Guo, Wei, Guo-Wei
Published in Journal of medicinal chemistry (14.09.2023)
Published in Journal of medicinal chemistry (14.09.2023)
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Journal Article
Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulations
Lin, Hong‐Yan, Yang, Jing‐Fang, Wang, Da‐Wei, Hao, Ge‐Fei, Dong, Jiang‐Qing, Wang, Yu‐Xia, Yang, Wen‐Chao, Wu, Jia‐Wei, Zhan, Chang‐Guo, Yang, Guang‐Fu
Published in The FEBS journal (01.03.2019)
Published in The FEBS journal (01.03.2019)
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Journal Article
Gender differences in cocaine‐induced hyperactivity and dopamine transporter trafficking to the plasma membrane
Deng, Jing, Zheng, Xirong, Shang, Linyue, Zhan, Chang‐Guo, Zheng, Fang
Published in Addiction biology (01.11.2022)
Published in Addiction biology (01.11.2022)
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Journal Article
Catalytic Mechanisms for Cofactor-Free Oxidase-Catalyzed Reactions: Reaction Pathways of Uricase-Catalyzed Oxidation and Hydration of Uric Acid
Wei, Donghui, Huang, Xiaoqin, Qiao, Yan, Rao, Jingjing, Wang, Lu, Liao, Fei, Zhan, Chang-Guo
Published in ACS catalysis (07.07.2017)
Published in ACS catalysis (07.07.2017)
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Journal Article
Unraveling the allosteric mechanisms of prolyl endopeptidases for celiac disease therapy: Insights from molecular dynamics simulations
Wang, Yongqiang, Xing, Suting, Zhao, Xinyun, Chen, Xi, Zhan, Chang-guo
Published in International journal of biological macromolecules (01.02.2024)
Published in International journal of biological macromolecules (01.02.2024)
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Journal Article
Effect of alcohol on chronic pelvic pain and prostatic inflammation in a mouse model of experimental autoimmune prostatitis
Zhang, Li‐Gang, Chen, Jing, Meng, Jia‐Lin, Zhang, Yong, Liu, Yi, Zhan, Chang‐Sheng, Chen, Xian‐Guo, Zhang, Li, Liang, Chao‐Zhao
Published in The Prostate (01.09.2019)
Published in The Prostate (01.09.2019)
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Journal Article
Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene
Zheng, Xirong, Chen, Xiabin, Zhang, Ting, Zhan, Max, Zhan, Chang-Guo, Zheng, Fang
Published in Organic & biomolecular chemistry (11.03.2020)
Published in Organic & biomolecular chemistry (11.03.2020)
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