Discovery of 7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide (CUDC-101) as a Potent Multi-Acting HDAC, EGFR, and HER2 Inhibitor for the Treatment of Cancer
Cai, Xiong, Zhai, Hai-Xiao, Wang, Jing, Forrester, Jeffrey, Qu, Hui, Yin, Ling, Lai, Cheng-Jung, Bao, Rudi, Qian, Changgeng
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
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Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling
CHANGGENG QIAN, LAI, Cheng-Jung, ZIFCAK, Brian, ANNA WAI SEE MA, DELLAROCCA, Steven, BOREK, Mylissa, ZHAI, Hai-Xiao, XIONG CAI, VOI, Maurizio, RUDI BAO, WANG, Da-Gong, JING WANG, XU, Guang-Xin, ATOYAN, Ruzanna, HUI QU, LING YIN, SAMSON, Maria
Published in Clinical cancer research (01.08.2012)
Published in Clinical cancer research (01.08.2012)
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CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity
LAI, Cheng-Jung, RUDI BAO, ZIFCAK, Brian, XU, Guang-Xin, DELLAROCCA, Steven, ZHAI, Hai-Xiao, XIONG CAI, MUNGER, William E, KEEGAN, Mitchell, PEPICELLI, Carmen V, CHANGGENG QIAN, XU TAO, JING WANG, ATOYAN, Ruzanna, HUI QU, WANG, Da-Gong, LING YIN, SAMSON, Maria, FORRESTER, Jeffrey
Published in Cancer research (Chicago, Ill.) (01.05.2010)
Published in Cancer research (Chicago, Ill.) (01.05.2010)
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Journal Article
CUDC-305, a Novel Synthetic HSP90 Inhibitor with Unique Pharmacologic Properties for Cancer Therapy
Bao, Rudi, Lai, Cheng-Jung, Qu, Hui, Wang, Dagong, Yin, Ling, Zifcak, Brian, Atoyan, Ruzanna, Wang, Jing, Samson, Maria, Forrester, Jeffrey, DellaRocca, Steven, Xu, Guang-Xin, Tao, Xu, Zhai, Hai-Xiao, Cai, Xiong, Qian, Changgeng
Published in Clinical cancer research (15.06.2009)
Published in Clinical cancer research (15.06.2009)
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Journal Article
Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non–small cell lung cancer
Bao, Rudi, Lai, Cheng-Jung, Wang, Da-Gong, Qu, Hui, Yin, Ling, Zifcak, Brian, Tao, Xu, Wang, Jing, Atoyan, Ruzanna, Samson, Maria, Forrester, Jeffrey, Xu, Guang-Xin, DellaRocca, Steven, Borek, Mylissa, Zhai, Hai-Xiao, Cai, Xiong, Qian, Changgeng
Published in Molecular cancer therapeutics (01.12.2009)
Published in Molecular cancer therapeutics (01.12.2009)
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Abstract C70: Antitumor activity of CUDC-907, a single small molecule inhibitor that targets both PI3K and HDAC, in hematologic cancer models
Bao, Rudi, Wang, Dagong, Qu, Hui, Wang, Jing, Atoyan, Ruzanna, Xu, Guang-Xin, Yin, Ling, Zifcak, Brian, Borek, Mylissa, Samson, Maria, Ma, Anna, DellaRocca, Steven, Zhai, Hai-Xiao, Lai, Cheng-Jung, Pepicelli, Carmen, Cai, Xiong, Qian, Changgeng
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract 3249: Design and synthesis of imidazopyridine derivatives as novel HSP90 inhibitors for the treatment of cancer
Cai, Xiong, Zhai, Hai-Xiao, Wang, Jing, Samson, Maria, Atoyan, Ruzanna, Forrester, Jeffrey, Qu, Hui, Yin, Ling, Wang, Dagong, Zifcak, Brian, DellaRocca, Steven, Xu, Guang-Xin, Lai, Cheng-Jung, Bao, Rudi, Simonin, Marie-Paule, Keegan, Mitchell, Pepicelli, Carmen V., Qian, Changgeng
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 2619: Potential advantages of CUDC-101, a multi-targeted HDAC, EGFR and HER2 inhibitor, on preventing drug resistance and tumor metastasis
Wang, Jing, Selmi, Kader, Samson, Maria, Forrester, Jeffrey, Atoyan, Ruzanna, Qu, Hui, Yin, Ling, Wang, Da-Gong, Zifcak, Brian, Borek, Mylissa, DellaRocca, Steven, Bao, Rudi, Zhai, Hai-Xiao, Cai, Xiong, Qian, Changgeng, Savagner, Pierre, Lai, Cheng-Jung
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 4469: Antitumor activity of a single small molecule agent targeting Pi3K/mTor and HDAC
Bao, Rudi, Lai, Cheng-Jung, Wang, Dagong, Qu, Hui, Yin, Ling, Zifcak, Brian, Tao, Xu, Wang, Jing, Zhai, Hai-Xiao, Xu, Guang-Xin, Borek, Mylissa, Atoyan, Ruzanna, Samson, Maria, Forrester, Jeffrey, Dellarocca, Steven, Cai, Xiong, Qian, Changgeng
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Feasibility study on expanded indication for endoscopic submucosal dissection of intramucosal poorly differentiated early gastric cancer
Li, Hua, Huo, Zhi-Bin, Chen, Shu-Bo, Li, Hui, Wu, Dian-Chao, Zhai, Tong-Shan, Xiao, Qi-Hai, Wang, Shu-Xia, Zhang, Li-Li
Published in World journal of gastroenterology : WJG (07.08.2016)
Published in World journal of gastroenterology : WJG (07.08.2016)
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Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2-deoxy-2-fluoro-scyllo-inositol-1-O-dodecylphosphonate and its analogs inhibit glycosylphosphatidylinositol phospholipase C
Morris, J C, Ping-Sheng, L, Zhai, H X, Shen, T Y, Mensa-Wilmot, K
Published in The Journal of biological chemistry (28.06.1996)
Published in The Journal of biological chemistry (28.06.1996)
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Journal Article
Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2- Deoxy-2-fluoro-scyllo-inositol-1-O-dodecyl phosphonate and its analogs inhibit glycosyl-phosphatidylinositol phospholipase C
Morris, J C, Sheng, L P, Zhai, Hai-Xiao, Shen, Tsung-Ying, Mensa-Wilmot, K
Published in The Journal of biological chemistry (01.01.1996)
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Published in The Journal of biological chemistry (01.01.1996)
Journal Article
Nonspecific Effect of Stress on Brain Gray Matter Volume in Drug-naive Female Patients with First Depressive Episode
Zhuo, Chuan-Jun, Bian, Hai-Man, Gao, Yan-Jie, Ma, Xiao-Lei, Ji, Sheng-Zhang, Yao, Meng-Yuan, Zhai, Ning, Sun, Xin-Hai, Ma, Xiao-Yan, Tian, Hong-Jun, Li, Gong-Ying
Published in Chinese medical journal (05.02.2016)
Published in Chinese medical journal (05.02.2016)
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