TH1902, a new docetaxel‐peptide conjugate for the treatment of sortilin‐positive triple‐negative breast cancer
Demeule, Michel, Charfi, Cyndia, Currie, Jean‐Christophe, Larocque, Alain, Zgheib, Alain, Kozelko, Sophie, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer science (01.10.2021)
Published in Cancer science (01.10.2021)
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Epigallocatechin Gallate Targeting of Membrane Type 1 Matrix Metalloproteinase-mediated Src and Janus Kinase/Signal Transducers and Activators of Transcription 3 Signaling Inhibits Transcription of Colony-stimulating Factors 2 and 3 in Mesenchymal Stromal Cells
Zgheib, Alain, Lamy, Sylvie, Annabi, Borhane
Published in The Journal of biological chemistry (10.05.2013)
Published in The Journal of biological chemistry (10.05.2013)
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Corrigendum: Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Zgheib, Alain, Cousineau, Isabelle, Lullier, Véronique, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Frontiers in immunology (28.02.2024)
Published in Frontiers in immunology (28.02.2024)
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The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells
Demeule, Michel, Charfi, Cyndia, Currie, Jean-Christophe, Zgheib, Alain, Danalache, Bogdan Alexandru, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Pharmaceutics (01.09.2022)
Published in Pharmaceutics (01.09.2022)
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Journal Article
Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Zgheib, Alain, Cousineau, Isabelle, Lullier, Véronique, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Frontiers in immunology (16.02.2024)
Published in Frontiers in immunology (16.02.2024)
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New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells
Charfi, Cyndia, Demeule, Michel, Currie, Jean-Christophe, Larocque, Alain, Zgheib, Alain, Danalache, Bogdan Alexandru, Ouanouki, Amira, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Frontiers in oncology (22.10.2021)
Published in Frontiers in oncology (22.10.2021)
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The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers
Currie, Jean-Christophe, Demeule, Michel, Charfi, Cyndia, Zgheib, Alain, Larocque, Alain, Danalache, Bogdan Alexandru, Ouanouki, Amira, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancers (08.04.2022)
Published in Cancers (08.04.2022)
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Olive oil compounds inhibit the paracrine regulation of TNF-α-induced endothelial cell migration through reduced glioblastoma cell cyclooxygenase-2 expression
Lamy, Sylvie, Ben Saad, Aroua, Zgheib, Alain, Annabi, Borhane
Published in The Journal of nutritional biochemistry (01.01.2016)
Published in The Journal of nutritional biochemistry (01.01.2016)
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Abstract 6362: TH1901, a novel curcumin-peptide conjugate for the treatment of Sortilin-positive (SORT1+) cancer
Annabi, Borhane, Demeule, Michel, Currie, Jean-Christophe, Larocque, Alain, Zgheib, Alain, Marsolais, Christian, Béliveau, Richard
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 685: Sortilin receptor-mediated novel cancer therapy: A targeted approach to inhibit vasculogenic mimicry in ovarian and breast cancers
Currie, Jean-Christophe, Demeule, Michel, Larocque, Alain, Zgheib, Alain, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1313: TH1902, a docetaxel peptide-drug conjugate, shows pre-clinical efficacy in several Sortilin-positive (SORT1+) cancers
Marsolais, Christian, Currie, Jean-Christophe, Demeule, Michel, Charfi, Cyndia, Larocque, Alain, Zgheib, Alain, Béliveau, Richard, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1439: Increasing potency of anticancer drugs through SORT1+ technology: A new targeted approach for the treatment of ovarian and endometrial cancers
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Larocque, Alain, Zgheib, Alain, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1061: Increasing potency of anticancer drugs through Sortilin receptor-mediated cancer therapy: A new targeted approach for the treatment of ovarian cancer
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Larocque, Alain, Zgheib, Alain, Kozelko, Sophie, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 2910: A novel Sortilin-targeted docetaxel peptide conjugate (TH1902), for the treatment of Sortilin-positive (SORT1+) triple-negative breast cancer
Marsolais, Christian, Charfi, Cyndia, Demeule, Michel, Currie, Jean-Christophe, Larocque, Alain, Zgheib, Alain, Duquette, Natacha, Béliveau, Richard, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract P3-10-07: Receptor-mediated chemotherapy using a new Docetaxel-peptide conjugate for Sortilin-positive triple-negative breast cancer
Demeule, Michel, Charfi, Cyndia, Currie, Jean-Christophe C, Larocque, Alain, Zgheib, Alain, Marsolais, Christian, Béliveau, Richard, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract 3364: Adaptive mechanisms upon LRP1 repression: Impact on sphingosine-1-phosphate-mediated signalling and migration of brain endothelial cells
Vézina, Amélie, Charfi, Cyndia, Zgheib, Alain, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 3717: Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Zgheib, Alain, Cousineau, Isabelle, Lullier, Veronique, Beliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 4499: The peptide-drug conjugate sudocetaxel zendusortide (TH1902) potentiates anti-tumoral activity of the anti-PD-L1 checkpoint inhibitor and induces immune cell infiltration in a B16-F10 syngeneic melanoma model
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Zgheib, Alain, Cousineau, Isabelle, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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