Development of new drugs for an old target: the penicillin binding proteins
Zervosen, Astrid, Sauvage, Eric, Frère, Jean-Marie, Charlier, Paulette, Luxen, André
Published in Molecules (Basel, Switzerland) (24.10.2012)
Published in Molecules (Basel, Switzerland) (24.10.2012)
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Synthesis and biological evaluation of potential threonine synthase inhibitors: Rhizocticin A and Plumbemycin A
Gahungu, Mathias, Arguelles-Arias, Anthony, Fickers, Patrick, Zervosen, Astrid, Joris, Bernard, Damblon, Christian, Luxen, André
Published in Bioorganic & medicinal chemistry (01.09.2013)
Published in Bioorganic & medicinal chemistry (01.09.2013)
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New noncovalent inhibitors of penicillin-binding proteins from penicillin-resistant bacteria
Turk, Samo, Verlaine, Olivier, Gerards, Thomas, Zivec, Matej, Humljan, Jan, Sosič, Izidor, Amoroso, Ana, Zervosen, Astrid, Luxen, André, Joris, Bernard, Gobec, Stanislav
Published in PloS one (09.05.2011)
Published in PloS one (09.05.2011)
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Synthesis of an enantiopure thioester as key substrate for screening the sensitivity of penicillin binding proteins to inhibitors
Simon, Justine F., Bouillez, André, Frère, Jean-Marie, Luxen, André, Zervosen, Astrid
Published in ARKIVOC (19.08.2016)
Published in ARKIVOC (19.08.2016)
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Synthesis and Evaluation of 3-(Dihydroxyboryl)benzoic Acids as d,d-Carboxypeptidase R39 Inhibitors
Inglis, Steven R, Zervosen, Astrid, Woon, Esther C. Y, Gerards, Thomas, Teller, Nathalie, Fischer, Delphine S, Luxen, André, Schofield, Christopher J
Published in Journal of medicinal chemistry (08.10.2009)
Published in Journal of medicinal chemistry (08.10.2009)
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Interactions between Penicillin-Binding Proteins (PBPs) and Two Novel Classes of PBP Inhibitors, Arylalkylidene Rhodanines and Arylalkylidene Iminothiazolidin-4-ones
ZERVOSEN, Astrid, LU, Wei-Ping, ZHOULIANG CHEN, WHITE, Ronald E, DEMUTH, Thomas P, FRERE, Jean-Marie
Published in Antimicrobial Agents and Chemotherapy (01.03.2004)
Published in Antimicrobial Agents and Chemotherapy (01.03.2004)
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Fully automated radiosynthesis of N(1)-[(18)F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging
Henrottin, Jean, Lemaire, Christian, Egrise, Dominique, Zervosen, Astrid, Van den Eynde, Benoit, Plenevaux, Alain, Franci, Xavier, Goldman, Serge, Luxen, André
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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Fully automated radiosynthesis of N 1 -[18 F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging
Henrottin, Jean, Lemaire, Christian, Egrise, Dominique, Zervosen, Astrid, Van den Eynde, Benoit, Plenevaux, Alain, Franci, Xavier, Goldman, Serge, Luxen, André
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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Synthesis of protected α-alkyl lanthionine derivatives
Denoël, Thibaut, Zervosen, Astrid, Lemaire, Christian, Plenevaux, Alain, Luxen, André
Published in Tetrahedron (29.07.2014)
Published in Tetrahedron (29.07.2014)
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Stereoselective synthesis of lanthionine derivatives in aqueous solution and their incorporation into the peptidoglycan of Escherichia coli
Denoël, Thibaut, Zervosen, Astrid, Gerards, Thomas, Lemaire, Christian, Joris, Bernard, Blanot, Didier, Luxen, André
Published in Bioorganic & medicinal chemistry (01.09.2014)
Published in Bioorganic & medicinal chemistry (01.09.2014)
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Synthesis of Nucleotide-Activated Oligosaccharides by ?-Galactosidase from Bacillus circulans
Zervosen, Astrid, Nieder, Veronika, Gallego, Ricardo Gutiérrez, Kamerling, Johannis P., Vliegenthart, Johannes F.G., Elling, Lothar
Published in Biological chemistry (12.01.2001)
Published in Biological chemistry (12.01.2001)
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N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase
Henrottin, Jean, Zervosen, Astrid, Lemaire, Christian, Sapunaric, Frédéric, Laurent, Sophie, Van den Eynde, Benoit, Goldman, Serge, Plenevaux, Alain, Luxen, André
Published in ACS medicinal chemistry letters (12.03.2015)
Published in ACS medicinal chemistry letters (12.03.2015)
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Enantioselective synthesis of α-benzylated lanthionines and related tripeptides for biological incorporation into E. coli peptidoglycanElectronic supplementary information (ESI) available. CCDC 958602 and 958603. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4ob01476f
Denoël, Thibaut, Zervosen, Astrid, Lemaire, Christian, Joris, Bernard, Hervé, Mireille, Blanot, Didier, Zaragoza, Guillermo, Luxen, André
Year of Publication 19.11.2014
Year of Publication 19.11.2014
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Enantioselective synthesis of alpha-benzylated lanthionines and related tripeptides for biological incorporation into E. coli peptidoglycan
Denoel, Thibaut, Zervosen, Astrid, Lemaire, Christian, Joris, Bernard, Herve, Mireille, Blanot, Didier, Zaragoza, Guillermo, Luxen, Andre
Published in Organic & biomolecular chemistry (28.12.2014)
Published in Organic & biomolecular chemistry (28.12.2014)
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Fully automated radiosynthesis of N1-[18F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging
Henrottin, Jean, Lemaire, Christian, Egrise, Dominique, Zervosen, Astrid, Van den Eynde, Benoit, Plenevaux, Alain, Franci, Xavier, Goldman, Serge, Luxen, André
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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N 1‑Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase
Henrottin, Jean, Zervosen, Astrid, Lemaire, Christian, Sapunaric, Frédéric, Laurent, Sophie, Van den Eynde, Benoit, Goldman, Serge, Plenevaux, Alain, Luxen, André
Published in ACS medicinal chemistry letters (12.03.2015)
Published in ACS medicinal chemistry letters (12.03.2015)
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Specific Structural Features of the N-Acetylmuramoyl- l-Alanine Amidase AmiD from Escherichia coli and Mechanistic Implications for Enzymes of This Family
Kerff, Frédéric, Petrella, Stéphanie, Mercier, Frédéric, Sauvage, Eric, Herman, Raphaël, Pennartz, Anne, Zervosen, Astrid, Luxen, André, Frère, Jean-Marie, Joris, Bernard, Charlier, Paulette
Published in Journal of molecular biology (19.03.2010)
Published in Journal of molecular biology (19.03.2010)
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Development of solid-supported methodology for the preparation of peptidoglycan fragments containing (2S,6R)-diaminopimelic acid
Simon, Justine F., Lamborelle, Nicolas, Zervosen, Astrid, Lemaire, Christian, Joris, Bernard, Luxen, André
Published in Tetrahedron letters (06.04.2016)
Published in Tetrahedron letters (06.04.2016)
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Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C
Zervosen, Astrid, Bouillez, André, Herman, Alexandre, Amoroso, Ana, Joris, Bernard, Sauvage, Eric, Charlier, Paulette, Luxen, André
Published in Bioorganic & medicinal chemistry (15.06.2012)
Published in Bioorganic & medicinal chemistry (15.06.2012)
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