Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator
Spear, Nathan, Gadient, Reto A., Wilkins, Deidre E., Do, MyLinh, Smith, Jeffrey S., Zeller, Kim L., Schroeder, Patricia, Zhang, Minli, Arora, Jalaj, Chhajlani, Vijay
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Published in European journal of pharmacology (01.06.2011)
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Anxiolytic-Like Effects of the Corticotropin-Releasing Factor1 (CRF1) Antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] Administered Acutely or Chronically at Doses Occupying Central CRF1 Receptors in Rats
Lelas, Snjezana, Wong, Harvey, Li, Yu-Wen, Heman, Karen L, Ward, Kathryn A, Zeller, Kim L, Sieracki, Kristine K, Polino, Joseph L, Godonis, Helen E, Ren, Shelly X, Yan, Xiao-Xin, Arneric, Stephen P, Robertson, David W, Hartig, Paul R, Grossman, Scott, Trainor, George L, Taub, Rebecca A, Zaczek, Robert, Gilligan, Paul J, McElroy, John F
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Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
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The CRF1 receptor antagonist DMP696 produces anxiolytic effects and inhibits the stress-induced hypothalamic-pituitary-adrenal axis activation without sedation or ataxia in rats
MCELROY, John F, WARD, Kathryn A, ZELLER, Kim L, JONES, Keith W, GILLIGAN, Paul J, LIQI HE, LELAS, Sniezana
Published in Psychopharmacologia (01.12.2002)
Published in Psychopharmacologia (01.12.2002)
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Synthesis and Structure−Activity Relationships of 8-(Pyrid-3-yl)pyrazolo[1,5-a]-1,3,5-triazines: Potent, Orally Bioavailable Corticotropin Releasing Factor Receptor-1 (CRF1) Antagonists
Gilligan, Paul J, Clarke, Todd, He, Liqi, Lelas, Snjezana, Li, Yu-Wen, Heman, Karen, Fitzgerald, Lawrence, Miller, Keith, Zhang, Ge, Marshall, Anne, Krause, Carol, McElroy, John F, Ward, Kathyrn, Zeller, Kim, Wong, Harvey, Bai, Steven, Saye, Joanne, Grossman, Scott, Zaczek, Robert, Arneric, Stephen P, Hartig, Paul, Robertson, David, Trainor, George
Published in Journal of medicinal chemistry (14.05.2009)
Published in Journal of medicinal chemistry (14.05.2009)
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The CRF 1 receptor antagonist DMP696 produces anxiolytic effects and inhibits the stress-induced hypothalamic-pituitary-adrenal axis activation without sedation or ataxia in rats
McElroy, John, Ward, Kathryn, Zeller, Kim, Jones, Keith, Gilligan, Paul, He, Liqi, Lelas, Snjezana
Published in Psychopharmacology (01.12.2002)
Published in Psychopharmacology (01.12.2002)
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The CRF(1) receptor antagonist DMP696 produces anxiolytic effects and inhibits the stress-induced hypothalamic-pituitary-adrenal axis activation without sedation or ataxia in rats
McElroy, John F, Ward, Kathryn A, Zeller, Kim L, Jones, Keith W, Gilligan, Paul J, He, Liqi, Lelas, Snjezana
Published in Psychopharmacology (01.12.2002)
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Published in Psychopharmacology (01.12.2002)
Journal Article
Anxiolytic-Like Effects of the Corticotropin-Releasing Factor 1 (CRF 1 ) Antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5- a ]-pyrimidine] Administered Acutely or Chronically at Doses Occupying Central CRF 1 Receptors in Rats
Lelas, Snjezana, Wong, Harvey, Li, Yu-Wen, Heman, Karen L., Ward, Kathryn A., Zeller, Kim L., Sieracki, Kristine K., Polino, Joseph L., Godonis, Helen E., Ren, Shelly X., Yan, Xiao-Xin, Arneric, Stephen P., Robertson, David W., Hartig, Paul R., Grossman, Scott, Trainor, George L., Taub, Rebecca A., Zaczek, Robert, Gilligan, Paul J., McElroy, John F.
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
Get full text
Journal Article