RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
Dannappel, Marius, Vlantis, Katerina, Kumari, Snehlata, Polykratis, Apostolos, Kim, Chun, Wachsmuth, Laurens, Eftychi, Christina, Lin, Juan, Corona, Teresa, Hermance, Nicole, Zelic, Matija, Kirsch, Petra, Basic, Marijana, Bleich, Andre, Kelliher, Michelle, Pasparakis, Manolis
Published in Nature (London) (04.09.2014)
Published in Nature (London) (04.09.2014)
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CSF1R signaling is a regulator of pathogenesis in progressive MS
Hagan, Nellwyn, Kane, John L., Grover, Deepak, Woodworth, Lisa, Madore, Charlotte, Saleh, Jacqueline, Sancho, Jose, Liu, Jinyu, Li, Yi, Proto, Jonathan, Zelic, Matija, Mahan, Amy, Kothe, Michael, Scholte, Andrew A., Fitzgerald, Maria, Gisevius, Barbara, Haghikia, Aiden, Butovsky, Oleg, Ofengeim, Dimitry
Published in Cell death & disease (23.10.2020)
Published in Cell death & disease (23.10.2020)
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RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4
Najjar, Malek, Saleh, Danish, Zelic, Matija, Nogusa, Shoko, Shah, Saumil, Tai, Albert, Finger, Joshua N., Polykratis, Apostolos, Gough, Peter J., Bertin, John, Whalen, Michael J., Pasparakis, Manolis, Balachandran, Siddharth, Kelliher, Michelle, Poltorak, Alexander, Degterev, Alexei
Published in Immunity (Cambridge, Mass.) (19.07.2016)
Published in Immunity (Cambridge, Mass.) (19.07.2016)
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Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo
Polykratis, Apostolos, Hermance, Nicole, Zelic, Matija, Roderick, Justine, Kim, Chun, Van, Trieu-My, Lee, Thomas H, Chan, Francis K M, Pasparakis, Manolis, Kelliher, Michelle A
Published in The Journal of immunology (1950) (15.08.2014)
Published in The Journal of immunology (1950) (15.08.2014)
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Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity
O'Donnell, Joanne A, Lehman, Jesse, Roderick, Justine E, Martinez-Marin, Dalia, Zelic, Matija, Doran, Ciara, Hermance, Nicole, Lyle, Stephen, Pasparakis, Manolis, Fitzgerald, Katherine A, Marshak-Rothstein, Ann, Kelliher, Michelle A
Published in The Journal of immunology (1950) (15.01.2018)
Published in The Journal of immunology (1950) (15.01.2018)
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Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
Roderick, Justine E., Hermance, Nicole, Zelic, Matija, Simmons, Matthew J., Polykratis, Apostolos, Pasparakis, Manolis, Kelliher, Michelle A.
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2014)
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Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide
Saleh, Danish, Najjar, Malek, Zelic, Matija, Shah, Saumil, Nogusa, Shoko, Polykratis, Apostolos, Paczosa, Michelle K, Gough, Peter J, Bertin, John, Whalen, Michael, Fitzgerald, Katherine A, Slavov, Nikolai, Pasparakis, Manolis, Balachandran, Siddharth, Kelliher, Michelle, Mecsas, Joan, Degterev, Alexei
Published in The Journal of immunology (1950) (01.06.2017)
Published in The Journal of immunology (1950) (01.06.2017)
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CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN
Legarda, Diana, Justus, Scott J., Ang, Rosalind L., Rikhi, Nimisha, Li, Wenjing, Moran, Thomas M., Zhang, Jianke, Mizoguchi, Emiko, Zelic, Matija, Kelliher, Michelle A., Blander, J. Magarian, Ting, Adrian T.
Published in Cell reports (Cambridge) (14.06.2016)
Published in Cell reports (Cambridge) (14.06.2016)
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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Wenzel, Jan, Lampe, Josephine, Müller-Fielitz, Helge, Schuster, Raphael, Zille, Marietta, Müller, Kristin, Krohn, Markus, Körbelin, Jakob, Zhang, Linlin, Özorhan, Ümit, Neve, Vanessa, Wagner, Julian U. G., Bojkova, Denisa, Shumliakivska, Mariana, Jiang, Yun, Fähnrich, Anke, Ott, Fabian, Sencio, Valentin, Robil, Cyril, Pfefferle, Susanne, Sauve, Florent, Coêlho, Caio Fernando Ferreira, Franz, Jonas, Spiecker, Frauke, Lembrich, Beate, Binder, Sonja, Feller, Nina, König, Peter, Busch, Hauke, Collin, Ludovic, Villaseñor, Roberto, Jöhren, Olaf, Altmeppen, Hermann C., Pasparakis, Manolis, Dimmeler, Stefanie, Cinatl, Jindrich, Püschel, Klaus, Zelic, Matija, Ofengeim, Dimitry, Stadelmann, Christine, Trottein, François, Nogueiras, Ruben, Hilgenfeld, Rolf, Glatzel, Markus, Prevot, Vincent, Schwaninger, Markus
Published in Nature neuroscience (01.11.2021)
Published in Nature neuroscience (01.11.2021)
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Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity
O'Donnell, Joanne A, Lehman, Jesse, Roderick, Justine E, Martinez-Marin, Dalia, Zelic, Matija, Doran, Ciara, Hermance, Nicole, Lyle, Stephen, Pasparakis, Manolis, Fitzgerald, Katherine A, Marshak-Rothstein, Ann, Kelliher, Michelle A
Published in The Journal of immunology (1950) (15.04.2018)
Published in The Journal of immunology (1950) (15.04.2018)
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Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
Ryan, Sean K., Zelic, Matija, Han, Yingnan, Teeple, Erin, Chen, Luoman, Sadeghi, Mahdiar, Shankara, Srinivas, Guo, Lilu, Li, Cong, Pontarelli, Fabrizio, Jensen, Elizabeth H., Comer, Ashley L., Kumar, Dinesh, Zhang, Mindy, Gans, Joseph, Zhang, Bailin, Proto, Jonathan D., Saleh, Jacqueline, Dodge, James C., Savova, Virginia, Rajpal, Deepak, Ofengeim, Dimitry, Hammond, Timothy R.
Published in Nature neuroscience (01.01.2023)
Published in Nature neuroscience (01.01.2023)
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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
Zelic, Matija, Pontarelli, Fabrizio, Woodworth, Lisa, Zhu, Cheng, Mahan, Amy, Ren, Yi, LaMorte, Michael, Gruber, Ross, Keane, Aislinn, Loring, Pequita, Guo, Lilu, Xia, Tai-he, Zhang, Boyao, Orning, Pontus, Lien, Egil, Degterev, Alexei, Hammond, Timothy, Ofengeim, Dimitry
Published in Cell reports (Cambridge) (11.05.2021)
Published in Cell reports (Cambridge) (11.05.2021)
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The SARS-CoV-2 main protease M pro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Wenzel, Jan, Lampe, Josephine, Müller-Fielitz, Helge, Schuster, Raphael, Zille, Marietta, Müller, Kristin, Krohn, Markus, Körbelin, Jakob, Zhang, Linlin, Özorhan, Ümit, Neve, Vanessa, Wagner, Julian U G, Bojkova, Denisa, Shumliakivska, Mariana, Jiang, Yun, Fähnrich, Anke, Ott, Fabian, Sencio, Valentin, Robil, Cyril, Pfefferle, Susanne, Sauve, Florent, Coêlho, Caio Fernando Ferreira, Franz, Jonas, Spiecker, Frauke, Lembrich, Beate, Binder, Sonja, Feller, Nina, König, Peter, Busch, Hauke, Collin, Ludovic, Villaseñor, Roberto, Jöhren, Olaf, Altmeppen, Hermann C, Pasparakis, Manolis, Dimmeler, Stefanie, Cinatl, Jindrich, Püschel, Klaus, Zelic, Matija, Ofengeim, Dimitry, Stadelmann, Christine, Trottein, François, Nogueiras, Ruben, Hilgenfeld, Rolf, Glatzel, Markus, Prevot, Vincent, Schwaninger, Markus
Published in Nature neuroscience (01.11.2021)
Published in Nature neuroscience (01.11.2021)
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RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome
Zelic, Matija, Roderick, Justine E, O'Donnell, Joanne A, Lehman, Jesse, Lim, Sung Eun, Janardhan, Harish P, Trivedi, Chinmay M, Pasparakis, Manolis, Kelliher, Michelle A
Published in The Journal of clinical investigation (01.05.2018)
Published in The Journal of clinical investigation (01.05.2018)
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Analyzing Necroptosis Using an RIPK1 Kinase Inactive Mouse Model of TNF Shock
Zelic, Matija, Kelliher, Michelle A
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
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전신성 과염증 반응을 수반하는 병태 치료에 사용하기 위한 에클리타세르팁
ZELIC MATIJA, CAMINIS JOHN, SCHNYDER SABINE, HARRIS KEITH, STAUDINGER HERIBERT, OFENGEIM DIMITRY, FLORIAN PETER
Year of Publication 06.01.2023
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Year of Publication 06.01.2023
Patent
Abstract B14: Hematopoietic RIPK1 deficiency results in bone marrow failure due to apoptosis and RIPK3-mediated necroptosis
Roderick, Justine R., Hermance, Nicole C., Zelic, Matija, Polykratis, Apostolos, Pasparakis, Manolis, Kelliher, Michelle A.
Published in Clinical cancer research (01.09.2015)
Published in Clinical cancer research (01.09.2015)
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RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation
Wong, Jerry, Garcia-Carbonell, Ricard, Zelic, Matija, Ho, Samuel B., Boland, Brigid S., Yao, Shih-Jing, Desai, Shalin A., Das, Soumita, Planell, Núria, Harris, Philip A., Font-Burgada, Joan, Taniguchi, Koji, Bertin, John, Salas, Azucena, Pasparakis, Manolis, Gough, Pete J., Kelliher, Michelle, Karin, Michael, Guma, Monica
Published in Cellular and molecular gastroenterology and hepatology (01.01.2020)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2020)
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Ripk-Mediated Necroptosis Induces Inflammation and Bone Marrow Failure in Mice
Roderick, Justine E., Hermance, Nicole, Zelic, Matija, Simmons, Matthew, Polykratis, Apostolos, Pasparakis, Manolis, Kelliher, Michelle
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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