The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs
Tsianou, Chrysostomi Christina, Kvetina, Jaroslav, Radochova, Vera, Kohoutova, Darina, Rejchrt, Stanislav, Valis, Martin, Zdarova Karasova, Jana, Tacheci, Ilja, Knoblochova, Veronika, Soukup, Ondrej, Bures, Jan
Published in PloS one (01.06.2023)
Published in PloS one (01.06.2023)
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A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice
Pejchal, Jaroslav, Jošt, Petr, Múčková, Lubica, Andrýs, Rudolf, Lísa, Miroslav, Zdarova Karasova, Jana
Published in Archives of toxicology (01.05.2022)
Published in Archives of toxicology (01.05.2022)
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Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?
Zdarova Karasova, Jana, Mzik, Martin, Kucera, Tomas, Vecera, Zbynek, Kassa, Jiri, Sestak, Vit
Published in International journal of molecular sciences (23.10.2020)
Published in International journal of molecular sciences (23.10.2020)
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The Impact of Dextran Sodium Sulfate-Induced Gastrointestinal Injury on the Pharmacokinetic Parameters of Donepezil and Its Active Metabolite 6- O -desmethyldonepezil, and Gastric Myoelectric Activity in Experimental Pigs
Bures, Jan, Tacheci, Ilja, Kvetina, Jaroslav, Radochova, Vera, Prchal, Lukas, Kohoutova, Darina, Valis, Martin, Novak, Martin, Dolezal, Rafael, Kopacova, Marcela, Rejchrt, Stanislav, Sestak, Vit, Knoblochova, Veronika, Peterova, Eva, Zdarova Karasova, Jana
Published in Molecules (Basel, Switzerland) (09.04.2021)
Published in Molecules (Basel, Switzerland) (09.04.2021)
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Dextran Sodium Sulphate-Induced Gastrointestinal Injury Further Aggravates the Impact of Galantamine on the Gastric Myoelectric Activity in Experimental Pigs
Bures, Jan, Tacheci, Ilja, Kvetina, Jaroslav, Radochova, Vera, Kohoutova, Darina, Valis, Martin, Rejchrt, Stanislav, Knoblochova, Veronika, Zdarova Karasova, Jana
Published in Pharmaceuticals (Basel, Switzerland) (18.06.2021)
Published in Pharmaceuticals (Basel, Switzerland) (18.06.2021)
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The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203
Kassa, Jiri, Misik, Jan, Hatlapatkova, Jana, Zdarova Karasova, Jana, Sepsova, Vendula, Caisberger, Filip, Pejchal, Jaroslav
Published in Molecules (Basel, Switzerland) (11.07.2017)
Published in Molecules (Basel, Switzerland) (11.07.2017)
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The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer’s Disease Patients and Its Consequence to Oxidative Stress Biomarkers
Valis, Martin, Herman, David, Vanova, Nela, Masopust, Jiri, Vysata, Oldrich, Hort, Jakub, Pavelek, Zbysek, Klimova, Blanka, Kuca, Kamil, Misik, Jan, Zdarova Karasova, Jana
Published in Frontiers in pharmacology (28.08.2019)
Published in Frontiers in pharmacology (28.08.2019)
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Time-dependent Changes in Concentration of Two Clinically Used Acetylcholinesterase Reactivators (HI-6 and Obidoxime) in Rat Plasma Determined by HPLC Techniques after in vivo Administration
KARASOVA, Jana ZDAROVA, NOVOTNY, Ladislav, ANTOS, Karel, ZIVNA, Helena, KUCA, Kamil
Published in Analytical Sciences (01.01.2010)
Published in Analytical Sciences (01.01.2010)
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3‐Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats
Dlabkova, Alzbeta, Herman, David, Cechova, Lenka, Hroch, Milos, Vanova, Nela, Zdarova Karasova, Jana
Published in Basic & clinical pharmacology & toxicology (01.09.2021)
Published in Basic & clinical pharmacology & toxicology (01.09.2021)
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Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870
Zdarova Karasova, Jana, Kassa, Jiri, Hepnarova, Vendula, Pejchal, Jaroslav, Junova, Lucie, Andrys, Rudolf, Malinak, David, Bzonek, Petr, Kohoutova, Zuzana, Musilek, Kamil
Published in Food and chemical toxicology (01.09.2022)
Published in Food and chemical toxicology (01.09.2022)
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Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness
Zdarova Karasova, Jana, Hepnarova, Vendula, Andrys, Rudolf, Lisa, Miroslav, Jost, Petr, Muckova, Lubica, Pejchal, Jaroslav, Herman, David, Jun, Daniel, Kassa, Jiri, Kuca, Kamil
Published in Toxicology letters (01.03.2020)
Published in Toxicology letters (01.03.2020)
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Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
Chalupova, Katarina, Korabecny, Jan, Bartolini, Manuela, Monti, Barbara, Lamba, Doriano, Caliandro, Rosanna, Pesaresi, Alessandro, Brazzolotto, Xavier, Gastellier, Anne-Julie, Nachon, Florian, Pejchal, Jaroslav, Jarosova, Michaela, Hepnarova, Vendula, Jun, Daniel, Hrabinova, Martina, Dolezal, Rafael, Zdarova Karasova, Jana, Mzik, Martin, Kristofikova, Zdena, Misik, Jan, Muckova, Lubica, Jost, Petr, Soukup, Ondrej, Benkova, Marketa, Setnicka, Vladimir, Habartova, Lucie, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Mezeiova, Eva, Uliassi, Elisa, Valis, Martin, Nepovimova, Eugenie, Bolognesi, Maria Laura, Kuca, Kamil
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Corrigendum to “The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer’s disease” [Biomed. Pharmacother. 159 (2023) 114223]
Valis, Martin, Dlabkova, Alzbeta, Hort, Jakub, Angelucci, Francesco, Pejchal, Jaroslav, Kuca, Kamil, Pavelek, Zbysek, Karasova, Jana Zdarova, Novotny, Michal
Published in Biomedicine & pharmacotherapy (01.09.2023)
Published in Biomedicine & pharmacotherapy (01.09.2023)
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The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer’s disease
Valis, Martin, Dlabkova, Alzbeta, Hort, Jakub, Angelucci, Francesco, Pejchal, Jaroslav, Kuca, Kamil, Pavelek, Zbysek, Karasova, Jana Zdarova, Novotny, Michal
Published in Biomedicine & pharmacotherapy (01.03.2023)
Published in Biomedicine & pharmacotherapy (01.03.2023)
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Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition
Misiachna, Anna, Konecny, Jan, Kolcheva, Marharyta, Ladislav, Marek, Prchal, Lukas, Netolicky, Jakub, Kortus, Stepan, Zahumenska, Petra, Langore, Emily, Novak, Martin, Hemelikova, Katarina, Hermanova, Zuzana, Hrochova, Michaela, Pelikanova, Anezka, Odvarkova, Jitka, Pejchal, Jaroslav, Kassa, Jiri, Zdarova Karasova, Jana, Korabecny, Jan, Soukup, Ondrej, Horak, Martin
Published in Biomedicine & pharmacotherapy (01.09.2024)
Published in Biomedicine & pharmacotherapy (01.09.2024)
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The New Acetylcholinesterase Inhibitors PC‐37 and PC‐48 (7‐Methoxytacrine‐Donepezil‐Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats
Zdarova Karasova, Jana, Mzik, Martin, Hroch, Milos, Korabecny, Jan, Nepovimova, Eugenie, Vorisek, Viktor, Palicka, Vladimir, Kuca, Kamil
Published in Basic & clinical pharmacology & toxicology (01.04.2018)
Published in Basic & clinical pharmacology & toxicology (01.04.2018)
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Encapsulation of oxime acetylcholinesterase reactivators: influence of physiological conditions on the stability of oxime-cucurbit[7]uril complexes
Andrýs, Rudolf, Kluso ová, Aneta, Lísa, Miroslav, d'árová Karasová, Jana
Published in New journal of chemistry (14.09.2020)
Published in New journal of chemistry (14.09.2020)
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A resurrection of 7-MEOTA: a comparison with tacrine
Soukup, Ondrej, Jun, Daniel, Zdarova-Karasova, Jana, Patocka, Jiri, Musilek, Kamil, Korabecny, Jan, Krusek, Jan, Kaniakova, Martina, Sepsova, Vendula, Mandikova, Jana, Trejtnar, Frantisek, Pohanka, Miroslav, Drtinova, Lucie, Pavlik, Michal, Tobin, Gunnar, Kuca, Kamil
Published in Current Alzheimer research (01.10.2013)
Published in Current Alzheimer research (01.10.2013)
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The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs
Bures, Jan, Kvetina, Jaroslav, Radochova, Vera, Tacheci, Ilja, Peterova, Eva, Herman, David, Dolezal, Rafael, Kopacova, Marcela, Rejchrt, Stanislav, Douda, Tomas, Sestak, Vit, Douda, Ladislav, Karasova, Jana Zdarova
Published in PloS one (24.01.2020)
Published in PloS one (24.01.2020)
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