Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors
Silk, Alain D., Zasadil, Lauren M., Holland, Andrew J., Vitre, Benjamin, Cleveland, Don W., Weaver, Beth A.
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
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Journal Article
Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles
Zasadil, Lauren M, Andersen, Kristen A, Yeum, Dabin, Rocque, Gabrielle B, Wilke, Lee G, Tevaarwerk, Amye J, Raines, Ronald T, Burkard, Mark E, Weaver, Beth A
Published in Science translational medicine (26.03.2014)
Published in Science translational medicine (26.03.2014)
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Journal Article
Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer
Denu, Ryan A, Zasadil, Lauren M, Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A, Burkard, Mark E
Published in BMC cancer (29.01.2016)
Published in BMC cancer (29.01.2016)
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Journal Article
High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability
Matson, Daniel R, Denu, Ryan A, Zasadil, Lauren M, Burkard, Mark E, Weaver, Beth A, Flynn, Christopher, Stukenberg, P Todd
Published in BMC cancer (23.02.2021)
Published in BMC cancer (23.02.2021)
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Journal Article
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons
Ryan, Sean D, Britigan, Eric M. C, Zasadil, Lauren M, Witte, Kristen, Audhya, Anjon, Roopra, Avtar, Weaver, Beth A
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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Journal Article
A Golgi-Localized Pool of the Mitotic Checkpoint Component Mad1 Controls Integrin Secretion and Cell Migration
Wan, Jun, Zhu, Fen, Zasadil, Lauren M., Yu, Jiaquan, Wang, Lei, Johnson, Adam, Berthier, Erwin, Beebe, David J., Audhya, Anjon, Weaver, Beth A.
Published in Current biology (17.11.2014)
Published in Current biology (17.11.2014)
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Journal Article
Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer
Choudhary, Alka, Zachek, Brittany, Lera, Robert F, Zasadil, Lauren M, Lasek, Amber, Denu, Ryan A, Kim, Hyunjung, Kanugh, Craig, Laffin, Jennifer J, Harter, Josephine M, Wisinski, Kari B, Saha, Sandeep, Weaver, Beth A, Burkard, Mark E
Published in Molecular cancer therapeutics (01.01.2016)
Published in Molecular cancer therapeutics (01.01.2016)
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Journal Article
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel
Scribano, Christina M, Wan, Jun, Esbona, Karla, Tucker, John B, Lasek, Amber, Zhou, Amber S, Zasadil, Lauren M, Molini, Ryan, Fitzgerald, Jonathan, Lager, Angela M, Laffin, Jennifer J, Correia-Staudt, Kayla, Wisinski, Kari B, Tevaarwerk, Amye J, O'Regan, Ruth, McGregor, Stephanie M, Fowler, Amy M, Chappell, Richard J, Bugni, Tim S, Burkard, Mark E, Weaver, Beth A
Published in Science translational medicine (08.09.2021)
Published in Science translational medicine (08.09.2021)
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Journal Article
High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation
Zasadil, Lauren M, Britigan, Eric M C, Ryan, Sean D, Kaur, Charanjeet, Guckenberger, David J, Beebe, David J, Moser, Amy R, Weaver, Beth A
Published in Molecular biology of the cell (01.07.2016)
Published in Molecular biology of the cell (01.07.2016)
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Journal Article
Abstract 2526: Polyploidy: A new breast cancer subtype and a lead compound that targets it with high selectivity
Burkard, Mark E., Choudhary, Alka, Lera, Robert F., Fedenia, Ross, Kanugh, Craig, Laffin, Jennifer J., Zasadil, Lauren M., Weaver, Beth A., Wisinski, Kari B.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons
Rayn, Sean D., Britigan, Eric M. C., Zasadil, Lauren M., Witte, Kristen, Audhya, Anjon, Roopra, Avtar, Weaver, Beth A.
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Journal Article