Germline Chd8 haploinsufficiency alters brain development in mouse
Gompers, Andrea L, Su-Feher, Linda, Ellegood, Jacob, Copping, Nycole A, Riyadh, M Asrafuzzaman, Stradleigh, Tyler W, Pride, Michael C, Schaffler, Melanie D, Wade, A Ayanna, Catta-Preta, Rinaldo, Zdilar, Iva, Louis, Shreya, Kaushik, Gaurav, Mannion, Brandon J, Plajzer-Frick, Ingrid, Afzal, Veena, Visel, Axel, Pennacchio, Len A, Dickel, Diane E, Lerch, Jason P, Crawley, Jacqueline N, Zarbalis, Konstantinos S, Silverman, Jill L, Nord, Alex S
Published in Nature neuroscience (01.08.2017)
Published in Nature neuroscience (01.08.2017)
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Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy
Napoli, Eleonora, Song, Gyu, Panoutsopoulos, Alexios, Riyadh, M. Asrafuzzaman, Kaushik, Gaurav, Halmai, Julian, Levenson, Richard, Zarbalis, Konstantinos S., Giulivi, Cecilia
Published in Scientific reports (27.07.2018)
Published in Scientific reports (27.07.2018)
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A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis
Shi, Jianting, Wu, Xun, Wang, Ziyi, Li, Fang, Meng, Yujiao, Moore, Rebecca M., Cui, Jian, Xue, Chenyi, Croce, Katherine R., Yurdagul, Arif, Doench, John G., Li, Wei, Zarbalis, Konstantinos S., Tabas, Ira, Yamamoto, Ai, Zhang, Hanrui
Published in Nature communications (24.12.2022)
Published in Nature communications (24.12.2022)
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Journal Article
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology
Orosco, Lori A., Ross, Adam P., Cates, Staci L., Scott, Sean E., Wu, Dennis, Sohn, Jiho, Pleasure, David, Pleasure, Samuel J., Adamopoulos, Iannis E., Zarbalis, Konstantinos S
Published in Nature communications (08.09.2014)
Published in Nature communications (08.09.2014)
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Correction: WDFY3 mutation alters laminar position and morphology of cortical neurons
Schaaf, Zachary A, Tat, Lyvin, Cannizzaro, Noemi, Panoutsopoulos, Alexios A, Green, Ralph, Rülicke, Thomas, Hippenmeyer, Simon, Zarbalis, Konstantinos S
Published in Molecular autism (31.01.2023)
Published in Molecular autism (31.01.2023)
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Prenatal folic acid and vitamin B12 imbalance alter neuronal morphology and synaptic density in the mouse neocortex
Tat, Lyvin, Cannizzaro, Noemi, Schaaf, Zachary, Racherla, Shailaja, Bottiglieri, Teodoro, Green, Ralph, Zarbalis, Konstantinos S.
Published in Communications biology (08.11.2023)
Published in Communications biology (08.11.2023)
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Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities
Panoutsopoulos, Alexios A., De Crescenzo, Angelo Harlan, Lee, Albert, Lu, Amelia MacKenzie, Ross, Adam P., Borodinsky, Laura N., Marcucio, Ralph, Trainor, Paul A., Zarbalis, Konstantinos S.
Published in Frontiers in cell and developmental biology (01.09.2020)
Published in Frontiers in cell and developmental biology (01.09.2020)
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A mutation in mouse Pak1ip1 causes orofacial clefting while human PAK1IP1 maps to 6p24 translocation breaking points associated with orofacial clefting
Ross, Adam P, Mansilla, M Adela, Choe, Youngshik, Helminski, Simon, Sturm, Richard, Maute, Roy L, May, Scott R, Hozyasz, Kamil K, Wójcicki, Piotr, Mostowska, Adrianna, Davidson, Beth, Adamopoulos, Iannis E, Pleasure, Samuel J, Murray, Jeffrey C, Zarbalis, Konstantinos S
Published in PloS one (25.07.2013)
Published in PloS one (25.07.2013)
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Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring
Harlan De Crescenzo, Angelo, Panoutsopoulos, Alexios A, Tat, Lyvin, Schaaf, Zachary, Racherla, Shailaja, Henderson, Lyle, Leung, Kit-Yi, Greene, Nicholas D E, Green, Ralph, Zarbalis, Konstantinos S
Published in Cerebral cortex (New York, N.Y. 1991) (01.01.2021)
Published in Cerebral cortex (New York, N.Y. 1991) (01.01.2021)
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Journal Article
Wdfy3 regulates glycophagy, mitophagy, and synaptic plasticity
Napoli, Eleonora, Panoutsopoulos, Alexios A, Kysar, Patricia, Satriya, Nathaniel, Sterling, Kira, Shibata, Bradley, Imai, Denise, Ruskin, David N, Zarbalis, Konstantinos S, Giulivi, Cecilia
Published in Journal of cerebral blood flow and metabolism (01.12.2021)
Published in Journal of cerebral blood flow and metabolism (01.12.2021)
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Maternal exposure to carbamazepine at environmental concentrations can cross intestinal and placental barriers
Kaushik, Gaurav, Huber, David P., Aho, Ken, Finney, Bruce, Bearden, Shawn, Zarbalis, Konstantinos S., Thomas, Michael A.
Published in Biochemical and biophysical research communications (27.05.2016)
Published in Biochemical and biophysical research communications (27.05.2016)
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Journal Article
Corrigendum to “Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis” [J. Autoimmun. 73C (2016) 73–84]
Wu, Dennis J., Gu, Ran, Sarin, Ritu, Zavodovskaya, Regina, Chen, Chia-Pei, Christiansen, Blaine A., Zarbalis, Konstantinos S., Adamopoulos, Iannis E.
Published in Journal of autoimmunity (01.11.2017)
Published in Journal of autoimmunity (01.11.2017)
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Journal Article
Prenatal folic acid and vitamin B 12 imbalance alter neuronal morphology and synaptic density in the mouse neocortex
Tat, Lyvin, Cannizzaro, Noemi, Schaaf, Zachary, Racherla, Shailaja, Bottiglieri, Teodoro, Green, Ralph, Zarbalis, Konstantinos S
Published in Communications biology (08.11.2023)
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Published in Communications biology (08.11.2023)
Journal Article
Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size
Le Duc, Diana, Giulivi, Cecilia, Hiatt, Susan M, Napoli, Eleonora, Panoutsopoulos, Alexios, Harlan De Crescenzo, Angelo, Kotzaeridou, Urania, Syrbe, Steffen, Anagnostou, Evdokia, Azage, Meron, Bend, Renee, Begtrup, Amber, Brown, Natasha J, Büttner, Benjamin, Cho, Megan T, Cooper, Gregory M, Doering, Jan H, Dubourg, Christèle, Everman, David B, Hildebrand, Michael S, Santos, Francis Jeshira Reynoso, Kellam, Barbara, Keller-Ramey, Jennifer, Lemke, Johannes R, Liu, Shuxi, Niyazov, Dmitriy, Payne, Katelyn, Person, Richard, Quélin, Chloé, Schnur, Rhonda E, Smith, Brooke T, Strober, Jonathan, Walker, Susan, Wallis, Mathew, Walsh, Laurence, Yang, Sandra, Yuen, Ryan K C, Ziegler, Andreas, Sticht, Heinrich, Pride, Michael C, Orosco, Lori, Martínez-Cerdeño, Verónica, Silverman, Jill L, Crawley, Jacqueline N, Scherer, Stephen W, Zarbalis, Konstantinos S, Jamra, Rami
Published in Brain (London, England : 1878) (01.09.2019)
Published in Brain (London, England : 1878) (01.09.2019)
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Journal Article
Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis
Wu, Dennis J, Gu, Ran, Sarin, Ritu, Zavodovskaya, Regina, Chen, Chia-Pei, Christiansen, Blaine A, Adamopoulos, Iannis E
Published in Journal of autoimmunity (01.09.2016)
Published in Journal of autoimmunity (01.09.2016)
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Journal Article
A Genome-wide CRISPR Screen Identifies WDFY3 as a Novel Regulator of Macrophage Efferocytosis
Shi, Jianting, Wu, Xun, Wang, Ziyi, Li, Fang, Meng, Yujiao, Moore, Rebecca M, Cui, Jian, Xue, Chenyi, Croce, Katherine R, Yurdagul, Arif, Doench, John G, Li, Wei, Zarbalis, Konstantinos S, Tabas, Ira, Yamamoto, Ai, Zhang, Hanrui
Published in bioRxiv (22.01.2022)
Published in bioRxiv (22.01.2022)
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