Structure-Function Relationships of the Raloxifene-Estrogen Receptor-α Complex for Regulating Transforming Growth Factor-α Expression in Breast Cancer Cells
Liu, Hong, Park, Woo-Chan, Bentrem, David J., McKian, Kevin P., Reyes, Alexander De Los, Loweth, Jessica A., Schafer, Jennifer MacGregor, Zapf, James W., Jordan, V. Craig
Published in The Journal of biological chemistry (15.03.2002)
Published in The Journal of biological chemistry (15.03.2002)
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Journal Article
Distinct molecular conformations of the estrogen receptor α complex exploited by environmental estrogens
BENTREM, David, FOX, Jennifer E, TIMM PEARCE, Sandra, HONG LIU, PAPPAS, Sam, KUPFER, David, ZAPF, James W, JORDAN, V. Craig
Published in Cancer research (Chicago, Ill.) (01.11.2003)
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Published in Cancer research (Chicago, Ill.) (01.11.2003)
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Abstract LB-16: Discovery of novel SGK1 inhibitors by a fragment-based approach: Generating patentable, chemically tractable and ligand efficient leads
Alton, Gordon, Wade, Warren, Lingardo, Laura, Batova, Ayse, Smart, Tom, Buhr, Chris, Zapf, James W., Pallai, Peter
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Substitution of glutamine for glutamic acid-58 in Escherichia coli thymidylate synthase results in pronounced decreases in catalytic activity and ligand binding
Zapf, James W, Weir, Mary S, Emerick, Victoria, Villafranca, J. E, Dunlap, R. Bruce
Published in Biochemistry (Easton) (14.09.1993)
Published in Biochemistry (Easton) (14.09.1993)
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High-Resolution NMR Structure and Backbone Dynamics of the Bacillus subtilis Response Regulator, Spo0F: Implications for Phosphorylation and Molecular Recognition
Feher, Victoria A, Zapf, James W, Hoch, James A, Whiteley, John M, McIntosh, Lawrence P, Rance, Mark, Skelton, Nicholas J, Dahlquist, Frederick W, Cavanagh, John
Published in Biochemistry (Easton) (19.08.1997)
Published in Biochemistry (Easton) (19.08.1997)
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Journal Article
Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex is induced by substituting glycine for aspartate at amino acid 351
SCHAFER, Jennifer Macgregor, HONG LIU, BENTREM, David J, ZAPF, James W, JORDAN, V. Craig
Published in Cancer research (Chicago, Ill.) (15.09.2000)
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Published in Cancer research (Chicago, Ill.) (15.09.2000)
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Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor α complex
HONG LIU, LEE, Eun-Sook, DE LOS REYES, Alexander, ZAPF, James W, JORDAN, V. Craig
Published in Cancer research (Baltimore) (01.05.2001)
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Published in Cancer research (Baltimore) (01.05.2001)
Conference Proceeding
Journal Article
Molecular classification of estrogens
JORDAN, V. Craig, SCHAFER, Jennifer Macgregor, LEVENSON, Anait S, HONG LIU, PEASE, Katherine M, SIMONS, Laura A, ZAPF, James W
Published in Cancer research (Chicago, Ill.) (15.09.2001)
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Published in Cancer research (Chicago, Ill.) (15.09.2001)
Journal Article
High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, SpoOf: Implications for phosphorylation and molecular recognition
Feher, V A, Zapf, J W, Hoch, JA, Whiteley, J M, McIntosh, L P, Rance, M, Skelton, N J, Dahlquist, F W, Cavanagh, J
Published in Biochemistry (Easton) (19.08.1997)
Published in Biochemistry (Easton) (19.08.1997)
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Journal Article
Structure-Function Relationships of the Raloxifene-Estrogen Receptor-α Complex for Regulating Transforming Growth Factor-α Expression in Breast Cancer Cells
Hong Liu, Woo-Chan Park, David J. Bentrem, Kevin P. McKian, Alexander De Los Reyes, Jessica A. Loweth, Jennifer MacGregor Schafer, James W. Zapf, V. Craig Jordan
Published in The Journal of biological chemistry (15.03.2002)
Published in The Journal of biological chemistry (15.03.2002)
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Journal Article
Molecular Mechanism of Action at Estrogen Receptor α of a New Clinically Relevant Antiestrogen (GW7604) Related to Tamoxifen1
Bentrem, David J, Dardes, Rita C, Liu, Hong, MacGregor-Schafer, Jennifer, Zapf, James W, Jordan, V. Craig
Published in Endocrinology (Philadelphia) (01.02.2001)
Published in Endocrinology (Philadelphia) (01.02.2001)
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Journal Article
Molecular Mechanism of Action at Estrogen Receptor α of a New Clinically Relevant Antiestrogen (GW7604) Related to TamoxifenThis work was supported by NIH CA-56143 (to V.C.J.); Fundaçao Coordenaçao de Aperfeiçoamento de Pessoal de Nível Superior, (CAPES) Scholarship, Brazil (to R.D.); the U.S. Army Medical Research and Material Command Breast Cancer Research Program, DAMD17–96-16169 (to H.L.); the generosity of the Lynn Sage Breast Cancer Research Foundation of Northwestern Memorial Hospital
Bentrem, David J., Dardes, Rita C., Liu, Hong, MacGregor-Schafer, Jennifer, Zapf, James W., Jordan, V. Craig
Published in Endocrinology (Philadelphia) (01.02.2001)
Published in Endocrinology (Philadelphia) (01.02.2001)
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Journal Article
KINASE ANTAGONISTS AND METHODS FOR MAKING AND USING THEM
WADE, Warren Stanfield, MEYER, Stephen Todd, GERENCSÉR, János, GYIMÓTHY, Balázs, ZAPF, James W
Year of Publication 30.01.2020
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Year of Publication 30.01.2020
Patent
Genetic complementation and resistance to 5-fluoro-2′-deoxyuridine in thymidine auxotrophs expressing a highly defective mutant of human thymidylate synthase
Zapf, James W., Zhao, Pei-shan, Steadman, David J., Berger, Sondra H.
Published in Biochemical pharmacology (15.09.1999)
Published in Biochemical pharmacology (15.09.1999)
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Journal Article
1H, 15N, and 13C backbone chemical shift assignments, secondary structure, and magnesium‐binding characteristics of the bacillus subtilis response regulator, SpoOF, determined by heteronuclear high‐resolution NMR
Feher, Victoria A., Zapf, James W., Hoch, James A., Dahlquist, Frederick W., Whiteley, John M., Cavanagh, John
Published in Protein science (01.09.1995)
Published in Protein science (01.09.1995)
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Journal Article
1 H, 15 N, and 13 C backbone chemical shift assignments, secondary structure, and magnesium-binding characteristics of the bacillus subtilis response regulator, SpoOF, determined by heteronuclear high-resolution NMR
Feher, Victoria A., Zapf, James W., Hoch, James A., Dahlquist, Frederick W., Whiteley, John M., Cavanagh, John
Published in Protein science (01.09.1995)
Published in Protein science (01.09.1995)
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Journal Article
Kinase antagonists and methods for making and using them
ZAPF, JAMES W, MEYER, STEPHEN TODD, GERENCSER, JANOS, GYIMOTHY, BALAZS, WADE, WARREN STANFIELD
Year of Publication 01.04.2020
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Year of Publication 01.04.2020
Patent