Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice
Zapata‐Pérez, Rubén, Tammaro, Alessandra, Schomakers, Bauke V., Scantlebery, Angelique M. L., Denis, Simone, Elfrink, Hyung L., Giroud‐Gerbetant, Judith, Cantó, Carles, López‐Leonardo, Carmen, McIntyre, Rebecca L., van Weeghel, Michel, Sánchez‐Ferrer, Álvaro, Houtkooper, Riekelt H.
Published in The FASEB journal (01.04.2021)
Published in The FASEB journal (01.04.2021)
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Journal Article
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans
Remie, Carlijn ME, Roumans, Kay HM, Moonen, Michiel PB, Connell, Niels J, Havekes, Bas, Mevenkamp, Julian, Lindeboom, Lucas, de Wit, Vera HW, van de Weijer, Tineke, Aarts, Suzanne ABM, Lutgens, Esther, Schomakers, Bauke V, Elfrink, Hyung L, Zapata-Pérez, Rubén, Houtkooper, Riekelt H, Auwerx, Johan, Hoeks, Joris, Schrauwen-Hinderling, Vera B, Phielix, Esther, Schrauwen, Patrick
Published in The American journal of clinical nutrition (01.08.2020)
Published in The American journal of clinical nutrition (01.08.2020)
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Journal Article
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
Tyrkalska, Sylwia D., Candel, Sergio, Angosto, Diego, Gómez-Abellán, Victoria, Martín-Sánchez, Fátima, García-Moreno, Diana, Zapata-Pérez, Rubén, Sánchez-Ferrer, Álvaro, Sepulcre, María P., Pelegrín, Pablo, Mulero, Victoriano
Published in Nature communications (01.07.2016)
Published in Nature communications (01.07.2016)
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Journal Article
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor
Giroud-Gerbetant, Judith, Joffraud, Magali, Giner, Maria Pilar, Cercillieux, Angelique, Bartova, Simona, Makarov, Mikhail V., Zapata-Pérez, Rubén, Sánchez-García, José L., Houtkooper, Riekelt H., Migaud, Marie E., Moco, Sofia, Canto, Carles
Published in Molecular metabolism (Germany) (01.12.2019)
Published in Molecular metabolism (Germany) (01.12.2019)
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Journal Article
Biochemical characterization of a new nicotinamidase from an unclassified bacterium thriving in a geothermal water stream microbial mat community
Zapata-Pérez, Rubén, Martínez-Moñino, Ana-Belén, García-Saura, Antonio-Ginés, Cabanes, Juana, Takami, Hideto, Sánchez-Ferrer, Álvaro
Published in PloS one (27.07.2017)
Published in PloS one (27.07.2017)
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Journal Article
Combined Whole-Cell High-Throughput Functional Screening for Identification of New Nicotinamidases/Pyrazinamidases in Metagenomic/Polygenomic Libraries
Zapata-Pérez, Rubén, García-Saura, Antonio G, Jebbar, Mohamed, Golyshin, Peter N, Sánchez-Ferrer, Álvaro
Published in Frontiers in microbiology (29.11.2016)
Published in Frontiers in microbiology (29.11.2016)
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Journal Article
Biochemical and mutational analysis of a novel nicotinamidase from Oceanobacillus iheyensis HTE831
Sánchez-Carrón, Guiomar, García-García, María Inmaculada, Zapata-Pérez, Rubén, Takami, Hideto, García-Carmona, Francisco, Sánchez-Ferrer, Alvaro
Published in PloS one (25.02.2013)
Published in PloS one (25.02.2013)
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Journal Article
Correction: Stimulating the sir2-spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome
Damschroder, Deena, Zapata-Pérez, Rubén, Richardson, Kristin, Vaz, Frédéric M, Houtkooper, Riekelt H, Wessells, Robert
Published in Disease models & mechanisms (01.09.2024)
Published in Disease models & mechanisms (01.09.2024)
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Journal Article
NAD+ homeostasis in human health and disease
Zapata‐Pérez, Rubén, Wanders, Ronald J A, van Karnebeek, Clara D M, Houtkooper, Riekelt H
Published in EMBO molecular medicine (07.07.2021)
Published in EMBO molecular medicine (07.07.2021)
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Journal Article
The female mouse is resistant to mild vitamin B3 deficiency
van der Stelt, Inge, Shi, Wenbiao, Bekkenkamp-Grovenstein, Melissa, Zapata-Pérez, Rubén, Houtkooper, Riekelt H., de Boer, Vincent C. J., Hegeman, Maria A., Keijer, Jaap
Published in European journal of nutrition (01.02.2022)
Published in European journal of nutrition (01.02.2022)
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Journal Article
Stimulating the sir2-spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome
Damschroder, Deena, Zapata-Pérez, Rubén, Richardson, Kristin, Vaz, Frédéric M, Houtkooper, Riekelt H, Wessells, Robert
Published in Disease models & mechanisms (01.10.2022)
Published in Disease models & mechanisms (01.10.2022)
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Journal Article
Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency
Martínez-Moñino, Ana Belén, Zapata-Pérez, Rubén, García-Saura, Antonio Ginés, Gil-Ortiz, Fernando, Pérez-Gilabert, Manuela, Sánchez-Ferrer, Álvaro
Published in PloS one (07.04.2017)
Published in PloS one (07.04.2017)
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Journal Article
An uncharacterized FMAG_01619 protein from Fusobacterium mortiferum ATCC 9817 demonstrates that some bacterial macrodomains can also act as poly-ADP-ribosylhydrolases
García-Saura, Antonio Ginés, Zapata-Pérez, Rubén, Hidalgo, José Francisco, Cabanes, Juana, Gil-Ortiz, Fernando, Sánchez-Ferrer, Álvaro
Published in Scientific reports (01.03.2019)
Published in Scientific reports (01.03.2019)
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Journal Article
A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome
Chatzispyrou, Iliana A., Alders, Marielle, Guerrero-Castillo, Sergio, Zapata Perez, Ruben, Haagmans, Martin A., Mouchiroud, Laurent, Koster, Janet, Ofman, Rob, Baas, Frank, Waterham, Hans R., Spelbrink, Johannes N., Auwerx, Johan, Mannens, Marcel M., Houtkooper, Riekelt H., Plomp, Astrid S.
Published in Human molecular genetics (01.07.2017)
Published in Human molecular genetics (01.07.2017)
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Journal Article
Biotechnological production of reduced and oxidized NAD+ precursors
Zapata-Pérez, Rubén, García-Saura, Antonio Ginés, Scantlebery, Angelique M.L., Schomakers, Bauke V., Rabadán-Ros, Rubén, van Weeghel, Michel, Houtkooper, Riekelt H., Sánchez-Ferrer, Álvaro
Published in Food research international (01.03.2023)
Published in Food research international (01.03.2023)
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Journal Article
Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis
Zapata-Pérez, Rubén, Gil-Ortiz, Fernando, Martínez-Moñino, Ana Belén, García-Saura, Antonio Ginés, Juanhuix, Jordi, Sánchez-Ferrer, Álvaro
Published in Open biology (01.04.2017)
Published in Open biology (01.04.2017)
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Journal Article
The female mouse is resistant to mild vitamin B 3 deficiency
van der Stelt, Inge, Shi, Wenbiao, Bekkenkamp-Grovenstein, Melissa, Zapata-Pérez, Rubén, Houtkooper, Riekelt H, de Boer, Vincent C J, Hegeman, Maria A, Keijer, Jaap
Published in European journal of nutrition (01.02.2022)
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Published in European journal of nutrition (01.02.2022)
Journal Article
A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome
Chatzispyrou, Iliana A, Alders, Marielle, Guerrero-Castillo, Sergio, Zapata Perez, Ruben, Haagmans, Martin A, Mouchiroud, Laurent, Koster, Janet, Ofman, Rob, Baas, Frank, Waterham, Hans R, Spelbrink, Johannes N, Auwerx, Johan, Mannens, Marcel M, Houtkooper, Riekelt H, Plomp, Astrid S
Published in Human molecular genetics (01.07.2017)
Published in Human molecular genetics (01.07.2017)
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Journal Article
A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA
Cánovas-Márquez, José Tomás, Falk, Sebastian, Nicolás, Francisco E, Padmanabhan, Subramanian, Zapata-Pérez, Rubén, Sánchez-Ferrer, Álvaro, Navarro, Eusebio, Garre, Victoriano
Published in Nucleic acids research (21.05.2021)
Published in Nucleic acids research (21.05.2021)
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Journal Article
A new cross-linked enzyme aggregate biocatalyst for NAD+-booster productionElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ra00505a
Martínez-Moñino, Ana-Belén, Zapata-Pérez, Rubén, García-Saura, Antonio-Ginés, Cabanes, Juana, Sánchez-Ferrer, Álvaro
Year of Publication 03.03.2017
Year of Publication 03.03.2017
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