Neuron Loss in Alzheimer's Disease: Translation in Transgenic Mouse Models
Wirths, Oliver, Zampar, Silvia
Published in International journal of molecular sciences (30.10.2020)
Published in International journal of molecular sciences (30.10.2020)
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Journal Article
Characterization of a Mouse Model of Alzheimer’s Disease Expressing Aβ4-42 and Human Mutant Tau
Zampar, Silvia, Wirths, Oliver
Published in International journal of molecular sciences (14.05.2021)
Published in International journal of molecular sciences (14.05.2021)
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Journal Article
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy
Kettwig, Matthias, Ternka, Katharina, Wendland, Kristin, Krüger, Dennis Manfred, Zampar, Silvia, Schob, Charlotte, Franz, Jonas, Aich, Abhishek, Winkler, Anne, Sakib, M. Sadman, Kaurani, Lalit, Epple, Robert, Werner, Hauke B., Hakroush, Samy, Kitz, Julia, Prinz, Marco, Bartok, Eva, Hartmann, Gunther, Schröder, Simone, Rehling, Peter, Henneke, Marco, Boretius, Susann, Alia, A., Wirths, Oliver, Fischer, Andre, Stadelmann, Christine, Nessler, Stefan, Gärtner, Jutta
Published in Nature communications (11.11.2021)
Published in Nature communications (11.11.2021)
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Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer’s disease
Marengo, Liana, Armbrust, Fred, Schoenherr, Caroline, Storck, Steffen E., Schmitt, Ulrich, Zampar, Silvia, Wirths, Oliver, Altmeppen, Hermann, Glatzel, Markus, Kaether, Christoph, Weggen, Sascha, Becker-Pauly, Christoph, Pietrzik, Claus U.
Published in Cellular and molecular life sciences : CMLS (01.03.2022)
Published in Cellular and molecular life sciences : CMLS (01.03.2022)
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The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease
Walter, Susanne, Jumpertz, Thorsten, Hüttenrauch, Melanie, Ogorek, Isabella, Gerber, Hermeto, Storck, Steffen E., Zampar, Silvia, Dimitrov, Mitko, Lehmann, Sandra, Lepka, Klaudia, Berndt, Carsten, Wiltfang, Jens, Becker-Pauly, Christoph, Beher, Dirk, Pietrzik, Claus U., Fraering, Patrick C., Wirths, Oliver, Weggen, Sascha
Published in Acta neuropathologica (01.02.2019)
Published in Acta neuropathologica (01.02.2019)
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Development and Technical Validation of an Immunoassay for the Detection of APP669–711 (Aβ−3–40) in Biological Samples
Klafki, Hans W., Rieper, Petra, Matzen, Anja, Zampar, Silvia, Wirths, Oliver, Vogelgsang, Jonathan, Osterloh, Dirk, Rohdenburg, Lara, Oberstein, Timo J., Jahn, Olaf, Beyer, Isaak, Lachmann, Ingolf, Knölker, Hans-Joachim, Wiltfang, Jens
Published in International journal of molecular sciences (08.09.2020)
Published in International journal of molecular sciences (08.09.2020)
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Journal Article
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
Depp, Constanze, Sun, Ting, Sasmita, Andrew Octavian, Spieth, Lena, Berghoff, Stefan A., Nazarenko, Taisiia, Overhoff, Katharina, Steixner-Kumar, Agnes A., Subramanian, Swati, Arinrad, Sahab, Ruhwedel, Torben, Möbius, Wiebke, Göbbels, Sandra, Saher, Gesine, Werner, Hauke B., Damkou, Alkmini, Zampar, Silvia, Wirths, Oliver, Thalmann, Maik, Simons, Mikael, Saito, Takashi, Saido, Takaomi, Krueger-Burg, Dilja, Kawaguchi, Riki, Willem, Michael, Haass, Christian, Geschwind, Daniel, Ehrenreich, Hannelore, Stassart, Ruth, Nave, Klaus-Armin
Published in Nature (London) (08.06.2023)
Published in Nature (London) (08.06.2023)
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Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice
Stazi, Martina, Zampar, Silvia, Nadolny, Madeleine, Büschgens, Luca, Meyer, Thomas, Wirths, Oliver
Published in European archives of psychiatry and clinical neuroscience (01.02.2023)
Published in European archives of psychiatry and clinical neuroscience (01.02.2023)
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Journal Article
The metalloprotease ADAMTS4 generates N-truncated A[beta]4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease
Walter, Susanne, Jumpertz, Thorsten, Hüttenrauch, Melanie, Ogorek, Isabella, Gerber, Hermeto, Storck, Steffen E, Zampar, Silvia
Published in Acta neuropathologica (01.02.2019)
Published in Acta neuropathologica (01.02.2019)
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N-Terminal Truncated Aβ4-42 Is a Substrate for Neprilysin Degradation in vitro and in vivo
Hornung, Karen, Zampar, Silvia, Engel, Nadine, Klafki, Hans, Liepold, Thomas, Bayer, Thomas A, Wiltfang, Jens, Jahn, Olaf, Wirths, Oliver
Published in Journal of Alzheimer's disease (2019)
Published in Journal of Alzheimer's disease (2019)
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Journal Article
Development and Technical Validation of an Immunoassay for the Detection of APP 669-711 (Aβ -3-40 ) in Biological Samples
Klafki, Hans W, Rieper, Petra, Matzen, Anja, Zampar, Silvia, Wirths, Oliver, Vogelgsang, Jonathan, Osterloh, Dirk, Rohdenburg, Lara, Oberstein, Timo J, Jahn, Olaf, Beyer, Isaak, Lachmann, Ingolf, Knölker, Hans-Joachim, Wiltfang, Jens
Published in International journal of molecular sciences (08.09.2020)
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Published in International journal of molecular sciences (08.09.2020)
Journal Article
Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer's disease
Depp, Constanze, Sun, Ting, Sasmita, Andrew Octavian, Spieth, Lena, Berghoff, Stefan A, Steixner-Kumar, Agnes A, Subramanian, Swati, Möbius, Wiebke, Göbbels, Sandra, Saher, Gesine, Zampar, Silvia, Wirths, Oliver, Thalmann, Maik, Saito, Takashi, Takaomi Saido, Krueger-Burg, Dilja, Kawaguchi, Riki, Willem, Michael, Haass, Christian, Geschwind, Daniel, Ehrenreich, Hannelore, Stassart, Ruth, Klaus-Armin Nave
Published in bioRxiv (02.08.2021)
Published in bioRxiv (02.08.2021)
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