Chagas Disease Treatment and Rational Drug Discovery: A Challenge That Remains
Silva, Ana Catarina Cristovão, Brelaz-de-Castro, Maria Carolina Accioly, Leite, Ana Cristina Lima, Pereira, Valéria Rêgo Alves, Hernandes, Marcelo Zaldini
Published in Frontiers in pharmacology (02.08.2019)
Published in Frontiers in pharmacology (02.08.2019)
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Combination of In Silico Methods in the Search for Potential CD4(+) and CD8(+) T Cell Epitopes in the Proteome of Leishmania braziliensis
E Silva, Rafael de Freitas, Ferreira, Luiz Felipe Gomes Rebello, Hernandes, Marcelo Zaldini, de Brito, Maria Edileuza Felinto, de Oliveira, Beatriz Coutinho, da Silva, Ailton Alvaro, de-Melo-Neto, Osvaldo Pompílio, Rezende, Antônio Mauro, Pereira, Valéria Rêgo Alves
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Published in Frontiers in immunology (29.08.2016)
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Development of inclusion complex based on cyclodextrin and oxazolidine derivative
Silva, Rafael Ramos, Amorim, Cézar Augusto da Cruz, Lima, Maria do Carmo Alves, Rabello, Marcelo Montenegro, Hernandes, Marcelo Zaldini, Rêgo, Moacyr Jesus Barreto de Melo, Pitta, Maira Galdino da Rocha, Oliveira, Maria Danielly Lima de, Andrade, César Augusto Souza de
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Published in Brazilian Journal of Pharmaceutical Sciences (01.01.2023)
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Immunogenicity of Potential CD4 + and CD8 + T Cell Epitopes Derived From the Proteome of Leishmania braziliensis
E Silva, Rafael de Freitas, de Oliveira, Beatriz Coutinho, da Silva, Ailton Alvaro, Brelaz de Castro, Maria Carolina Accioly, Ferreira, Luiz Felipe Gomes Rebello, Hernandes, Marcelo Zaldini, de Brito, Maria Edileuza Felinto, de-Melo-Neto, Osvaldo Pompílio, Rezende, Antônio Mauro, Pereira, Valéria Rêgo Alves
Published in Frontiers in immunology (14.02.2020)
Published in Frontiers in immunology (14.02.2020)
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1,3-Thiazole derivatives as privileged structures for anti-Trypanosoma cruzi activity: Rational design, synthesis, in silico and in vitro studies
Cox Holanda de Barros Dias, Mabilly, Souza Barbalho, Mayara, Bezerra de Oliveira Filho, Gevanio, Veríssimo de Oliveira Cardoso, Marcos, Lima Leite, Ana Cristina, da Silva Santos, Aline Caroline, Cristovão Silva, Ana Catarina, Accioly Brelaz de Castro, Maria Carolina, Maria Nascimento Moura, Danielle, Gomes Rebello Ferreira, Luiz Felipe, Zaldini Hernandes, Marcelo, de Freitas e Silva, Rafael, Rêgo Alves Pereira, Valéria
Published in European journal of medicinal chemistry (05.09.2023)
Published in European journal of medicinal chemistry (05.09.2023)
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CycloMolder software: building theoretical cyclodextrin derivatives models and evaluating their host:guest interactions
Montenegro Rabello, Marcelo, Rolim, Larissa Araújo, Rolim Neto, Pedro José, Hernandes, Marcelo Zaldini
Published in Journal of inclusion phenomena and macrocyclic chemistry (15.04.2019)
Published in Journal of inclusion phenomena and macrocyclic chemistry (15.04.2019)
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Synthesis and anti-inflammatory activity of new arylidene-thiazolidine-2,4-diones as PPARγ ligands
Barros, Cleiton Diniz, Amato, Angélica Amorim, Oliveira, Tiago Bento de, Iannini, Karime Bicas Rocha, Silva, Anekécia Lauro da, Silva, Teresinha Gonçalves da, Leite, Elisa Soares, Hernandes, Marcelo Zaldini, Lima, Maria do Carmo Alves de, Galdino, Suely Lins, Neves, Francisco de Assis Rocha, Pitta, Ivan da Rocha
Published in Bioorganic & medicinal chemistry (01.06.2010)
Published in Bioorganic & medicinal chemistry (01.06.2010)
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Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities
Cardoso, Marcos Veríssimo de Oliveira, Moreira, Diogo Rodrigo Magalhães, Filho, Gevanio Bezerra Oliveira, Cavalcanti, Suellen Melo Tiburcio, Coelho, Lucas Cunha Duarte, Espíndola, José Wanderlan Pontes, Gonzalez, Laura Rubio, Rabello, Marcelo Montenegro, Hernandes, Marcelo Zaldini, Ferreira, Paulo Michel Pinheiro, Pessoa, Cláudia, Alberto de Simone, Carlos, Guimarães, Elisalva Teixeira, Soares, Milena Botelho Pereira, Leite, Ana Cristina Lima
Published in European journal of medicinal chemistry (26.05.2015)
Published in European journal of medicinal chemistry (26.05.2015)
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Synthesis, Cruzain Docking, and in vitro Studies of Aryl-4-Oxothiazolylhydrazones Against Trypanosoma cruzi
Leite, Ana Cristina Lima, de M. Moreira, Diogo Rodrigo, de O. Cardoso, Marcos V., Hernandes, Marcelo Zaldini, Alves Pereira, Valéria R., Silva, Ricardo O., Kiperstok, Alice C., da S. Lima, Milena, Soares, Milena B. P.
Published in ChemMedChem (10.09.2007)
Published in ChemMedChem (10.09.2007)
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Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents
Hernandes, Marcelo Zaldini, Rabello, Marcelo Montenegro, Leite, Ana Cristina Lima, Cardoso, Marcos Veríssimo Oliveira, Moreira, Diogo Rodrigo Magalhaes, Brondani, Dalci José, Simone, Carlos Alberto, Reis, Luiza Campos, Souza, Marina Assis, Pereira, Valéria Rego Alves, Ferreira, Rafaela Salgado, McKerrow, James Hobson
Published in Bioorganic & medicinal chemistry (15.11.2010)
Published in Bioorganic & medicinal chemistry (15.11.2010)
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Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi
Leite, Ana Cristina Lima, de Lima, Renata Souza, Moreira, Diogo Rodrigo de M., Cardoso, Marcos Veríssimo de O., Gouveia de Brito, Ana Carolina, Farias dos Santos, Luciene Maria, Hernandes, Marcelo Zaldini, Kiperstok, Alice Costa, de Lima, Ricardo Santana, Soares, Milena B.P.
Published in Bioorganic & medicinal chemistry (01.06.2006)
Published in Bioorganic & medicinal chemistry (01.06.2006)
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Synthesis, biological evaluation and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities
da Costa Leite, Lúcia Fernanda C., Veras Mourão, Rosa Helena, de Lima, Maria do Carmo Alves, Galdino, Suely Lins, Hernandes, Marcelo Zaldini, de Assis Rocha Neves, Francisco, Vidal, Stéphanie, Barbe, Jacques, da Rocha Pitta, Ivan
Published in European journal of medicinal chemistry (01.10.2007)
Published in European journal of medicinal chemistry (01.10.2007)
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Halogen atoms in the modern medicinal chemistry: hints for the drug design
Hernandes, Marcelo Zaldini, Cavalcanti, Suellen Melo T, Moreira, Diogo Rodrigo M, de Azevedo Junior, Walter Filgueira, Leite, Ana Cristina Lima
Published in Current drug targets (01.03.2010)
Published in Current drug targets (01.03.2010)
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NPCdc, a synthetic natriuretic peptide, is a substrate to neprilysin and enhances blood pressure-lowering induced by enalapril in 5/6 nephrectomized rats
Aires, Regina Souza, Francisco da Silva Filho, Linaldo, Gomes Rebello Ferreira, Luiz Felipe, Hernandes, Marcelo Zaldini, Machado Marcondes, Marcelo Ferreira, Carmona, Adriana Karaoglanovic, Oliveira da Paixão, Ana Durce, Vieira, Leucio Duarte
Published in Toxicon (Oxford) (01.11.2021)
Published in Toxicon (Oxford) (01.11.2021)
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2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation
Cardoso, Marcos Veríssimo de Oliveira, Siqueira, Lucianna Rabelo Pessoa de, Silva, Elany Barbosa da, Costa, Lívia Bandeira, Hernandes, Marcelo Zaldini, Rabello, Marcelo Montenegro, Ferreira, Rafaela Salgado, da Cruz, Luana Faria, Magalhães Moreira, Diogo Rodrigo, Pereira, Valéria Rêgo Alves, de Castro, Maria Carolina Accioly Brelaz, Bernhardt, Paul V., Leite, Ana Cristina Lima
Published in European journal of medicinal chemistry (30.10.2014)
Published in European journal of medicinal chemistry (30.10.2014)
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In vitro bioevaluation and docking study of dihydrosphingosine and ethambutol analogues against sensitive and multi-drug resistant Mycobacterium tuberculosis
Linhares, Leonardo Aquino, dos Santos Peixoto, Aline, Correia de Sousa, Luanna de Angelis, Lucena Laet, João Paulo, da Silva Santos, Aline Caroline, Alves Pereira, Valeria Rêgo, Carneiro Neves, Maria Madileuza, Ferreira, Luiz Felipe Gomes Rebello, Hernandes, Marcelo Zaldini, de la Vega, Jennifer, Pereira-Neves, Antônio, San Feliciano, Arturo, Olmo, Esther Del, Schindler, Haiana Charifker, Montenegro, Lílian Maria Lapa
Published in European journal of medicinal chemistry (05.10.2023)
Published in European journal of medicinal chemistry (05.10.2023)
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Trypanosoma cruzi killing and immune response boosting by novel phenoxyhydrazine-thiazole against Chagas disease
Cristovão-Silva, Ana Catarina, Brelaz-de-Castro, Maria Carolina Accioly, Dionisio da Silva, Elis, Leite, Ana Cristina Lima, Santiago, Lizandra Beatriz Amorim Alves, Conceição, Juliana Maria da, da Silva Tiburcio, Robert, de Santana, Davi Pereira, Bedor, Danilo Cesar Galindo, de Carvalho, Breno Ítalo Valença, Ferreira, Luiz Felipe Gomes Rebello, de Freitas e Silva, Rafael, Alves Pereira, Valéria Rêgo, Hernandes, Marcelo Zaldini
Published in Experimental parasitology (01.06.2024)
Published in Experimental parasitology (01.06.2024)
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