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Published in Clinical cancer research (15.09.2012)
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EGFR exon 20 insertion mutations in lung adenocarcinomas: prevalence, molecular heterogeneity, and clinicopathologic characteristics
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Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers
YU, Helena A, ARCILA, Maria E, REKHTMAN, Natasha, SIMA, Camelia S, ZAKOWSKI, Maureen F, PAO, William, KRIS, Mark G, MILLER, Vincent A, LADANYI, Marc, RIELY, Gregory J
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Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas
Drilon, Alexander, Wang, Lu, Hasanovic, Adnan, Suehara, Yoshiyuki, Lipson, Doron, Stephens, Phil, Ross, Jeffrey, Miller, Vincent, Ginsberg, Michelle, Zakowski, Maureen F, Kris, Mark G, Ladanyi, Marc, Rizvi, Naiyer
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The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
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Clarifying the Spectrum of Driver Oncogene Mutations in Biomarker-Verified Squamous Carcinoma of Lung: Lack of EGFR/KRAS and Presence of PIK3CA/AKT1 Mutations
REKHTMAN, Natasha, PAIK, Paul K, ARCILA, Maria E, TAFE, Laura J, OXNARD, Geoffrey R, MOREIRA, Andre L, TRAVIS, William D, ZAKOWSKI, Maureen F, KRIS, Mark G, LADANYI, Marc
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Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
Pao, William, Miller, Vincent A, Politi, Katerina A, Riely, Gregory J, Somwar, Romel, Zakowski, Maureen F, Kris, Mark G, Varmus, Harold
Published in PLoS medicine (01.03.2005)
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Rebiopsy of Lung Cancer Patients with Acquired Resistance to EGFR Inhibitors and Enhanced Detection of the T790M Mutation Using a Locked Nucleic Acid-Based Assay
ARCILA, Maria E, OXNARD, Geoffrey R, NAFA, Khedoudja, RIELY, Gregory J, SOLOMON, Stephen B, ZAKOWSKI, Maureen F, KRIS, Mark G, PAO, William, MILLER, Vincent A, LADANYI, Marc
Published in Clinical cancer research (01.03.2011)
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Identification of KIF5B-RET and GOPC-ROS1 Fusions in Lung Adenocarcinomas through a Comprehensive mRNA-Based Screen for Tyrosine Kinase Fusions
SUEHARA, Yoshiyuki, ARCILA, Maria, KRIS, Mark G, ZAKOWSKI, Maureen F, RIZVI, Naiyer, KHANIN, Raya, LADANYI, Marc, LU WANG, HASANOVIC, Adnan, ANG, Daphne, ITO, Tatsuo, KIMURA, Yuki, DRILON, Alexander, GUHA, Udayan, RUSCH, Valerie
Published in Clinical cancer research (15.12.2012)
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KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
Pao, William, Wang, Theresa Y, Riely, Gregory J, Miller, Vincent A, Pan, Qiulu, Ladanyi, Marc, Zakowski, Maureen F, Heelan, Robert T, Kris, Mark G, Varmus, Harold E
Published in PLoS medicine (01.01.2005)
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High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)
Gong, Yixuan, Yao, Evelyn, Shen, Ronglai, Goel, Aviva, Arcila, Maria, Teruya-Feldstein, Julie, Zakowski, Maureen F, Frankel, Stanley, Peifer, Martin, Thomas, Roman K, Ladanyi, Marc, Pao, William
Published in PloS one (06.10.2009)
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Suitability of Thoracic Cytology for New Therapeutic Paradigms in Non-small Cell Lung Carcinoma: High Accuracy of Tumor Subtyping and Feasibility of EGFR and KRAS Molecular Testing
Rekhtman, Natasha, Brandt, Suzanne M., Sigel, Carlie S., Friedlander, Maria A., Riely, Gregory J., Travis, William D., Zakowski, Maureen F., Moreira, Andre L.
Published in Journal of thoracic oncology (01.03.2011)
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Incidence of EGFR Exon 19 Deletions and L858R in Tumor Specimens From Men and Cigarette Smokers With Lung Adenocarcinomas
D'ANGELO, Sandra P, CATHERINE PIETANZA, M, JOHNSON, Melissa L, RIELY, Gregory J, MILLER, Vincent A, SIMA, Camelia S, ZAKOWSKI, Maureen F, RUSCH, Valerie W, LADANYI, Marc, KRIS, Mark G
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors
Politi, Katerina, Zakowski, Maureen F, Fan, Pang-Dian, Schonfeld, Emily A, Pao, William, Varmus, Harold E
Published in Genes & development (01.06.2006)
Published in Genes & development (01.06.2006)
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Novel D761Y and Common Secondary T790M Mutations in Epidermal Growth Factor Receptor–Mutant Lung Adenocarcinomas with Acquired Resistance to Kinase Inhibitors
BALAK, Marissa N, YIXUAN GONG, LADANYI, Marc, MILLER, Vincent A, PAOL, William, RIELY, Gregory J, SOMWAR, Romel, LI, Allan R, ZAKOWSKI, Maureen F, CHIANG, Anne, GUANGLI YANG, OUERFELLI, Ouathek, KRIS, Mark G
Published in Clinical cancer research (01.11.2006)
Published in Clinical cancer research (01.11.2006)
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Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling
Chaft, Jamie E, Arcila, Maria E, Paik, Paul K, Lau, Christopher, Riely, Gregory J, Pietanza, M Catherine, Zakowski, Maureen F, Rusch, Valerie, Sima, Camelia S, Ladanyi, Marc, Kris, Mark G
Published in Molecular cancer therapeutics (01.02.2012)
Published in Molecular cancer therapeutics (01.02.2012)
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Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer
Regales, Lucia, Gong, Yixuan, Shen, Ronglai, de Stanchina, Elisa, Vivanco, Igor, Goel, Aviva, Koutcher, Jason A, Spassova, Maria, Ouerfelli, Ouathek, Mellinghoff, Ingo K, Zakowski, Maureen F, Politi, Katerina A, Pao, William
Published in The Journal of clinical investigation (01.10.2009)
Published in The Journal of clinical investigation (01.10.2009)
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