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Homocystamide Conjugates of Human Serum Albumin as a Platform to Prepare Bimodal Multidrug Delivery Systems for Boron Neutron Capture Therapy
Popova, Tatyana, Dymova, Maya A., Koroleva, Ludmila S., Zakharova, Olga D., Lisitskiy, Vladimir A., Raskolupova, Valeria I., Sycheva, Tatiana, Taskaev, Sergei, Silnikov, Vladimir N., Godovikova, Tatyana S.
Published in Molecules (Basel, Switzerland) (29.10.2021)
Published in Molecules (Basel, Switzerland) (29.10.2021)
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Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments
Munkuev, Aldar A., Mozhaitsev, Evgenii S., Chepanova, Arina A., Suslov, Evgeniy V., Korchagina, Dina V., Zakharova, Olga D., Ilina, Ekaterina S., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Molecules (Basel, Switzerland) (24.05.2021)
Published in Molecules (Basel, Switzerland) (24.05.2021)
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Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors
Salomatina, Oksana, Popadyuk, Irina, Zakharenko, Alexandra, Zakharova, Olga, Fadeev, Dmitriy, Komarova, Nina, Reynisson, Jóhannes, Arabshahi, H., Chand, Raina, Volcho, Konstantin, Salakhutdinov, Nariman, Lavrik, Olga
Published in Molecules (Basel, Switzerland) (17.03.2018)
Published in Molecules (Basel, Switzerland) (17.03.2018)
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Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments
Mozhaitsev, Evgenii S, Zakharenko, Alexandra L, Suslov, Evgeniy V, Korchagina, Dina V, Zakharova, Olga D, Vasil'eva, Inna A, Chepanova, Arina A, Black, Ellena, Patel, Jinal, Chand, Raina, Reynisson, Jóhannes, Leung, Ivanhoe K H, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in Anti-cancer agents in medicinal chemistry (01.01.2019)
Published in Anti-cancer agents in medicinal chemistry (01.01.2019)
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Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy
Komarova, Anastasia O., Drenichev, Mikhail S., Dyrkheeva, Nadezhda S., Kulikova, Irina V., Oslovsky, Vladimir E., Zakharova, Olga D., Zakharenko, Alexandra L., Mikhailov, Sergey N., Lavrik, Olga I.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
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Rational Design of Albumin Theranostic Conjugates for Gold Nanoparticles Anticancer Drugs: Where the Seed Meets the Soil?
Popova, Tatyana V., Pyshnaya, Inna A., Zakharova, Olga D., Akulov, Andrey E., Shevelev, Oleg B., Poletaeva, Julia, Zavjalov, Evgenii L., Silnikov, Vladimir N., Ryabchikova, Elena I., Godovikova, Tatyana S.
Published in Biomedicines (13.01.2021)
Published in Biomedicines (13.01.2021)
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The Development of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges
Chepanova, Arina A., Mozhaitsev, Evgenii S., Munkuev, Aldar A., Suslov, Evgeniy V., Korchagina, Dina V., Zakharova, Olga D., Zakharenko, Alexandra L., Patel, Jinal, Ayine-Tora, Daniel M., Reynisson, Jóhannes, Leung, Ivanhoe K. H., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Applied sciences (01.07.2019)
Published in Applied sciences (01.07.2019)
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Antibodies to HIV integrase catalyze site-specific degradation of their antigen
Odintsova, Elena S., Baranova, Svetlana V., Dmitrenok, Pavel S., Rasskazov, Valeriy A., Calmels, Christina, Parissi, Vincent, Andreola, Marie-Line, Buneva, Valentina N., Zakharova, Olga D., Nevinsky, Georgy A.
Published in International immunology (01.10.2011)
Published in International immunology (01.10.2011)
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Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure–activity relationship and molecular modeling study
Salomatina, Oksana V., Popadyuk, Irina I., Zakharenko, Alexandra L., Zakharova, Olga D., Chepanova, Arina A., Dyrkheeva, Nadezhda.S., Komarova, Nina I., Reynisson, Jóhannes, Anarbaev, Rashid O., Salakhutdinov, Nariman F., Lavrik, Olga I., Volcho, Konstantin P.
Published in Steroids (01.01.2021)
Published in Steroids (01.01.2021)
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Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy
Khomenko, Tatyana M., Zakharenko, Alexandra L., Chepanova, Arina A., Ilina, Ekaterina S., Zakharova, Olga D., Kaledin, Vasily I., Nikolin, Valeriy P., Popova, Nelly A., Korchagina, Dina V., Reynisson, Jóhannes, Chand, Raina, Ayine-Tora, Daniel M., Patel, Jinal, Leung, Ivanhoe K. H., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in International journal of molecular sciences (23.12.2019)
Published in International journal of molecular sciences (23.12.2019)
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New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors
Filimonov, Aleksander S., Chepanova, Arina A., Luzina, Olga A., Zakharenko, Alexandra L., Zakharova, Olga D., Ilina, Ekaterina S., Dyrkheeva, Nadezhda S., Kuprushkin, Maxim S., Kolotaev, Anton V., Khachatryan, Derenik S., Patel, Jinal, Leung, Ivanhoe K.H., Chand, Raina, Ayine-Tora, Daniel M., Reynisson, Johannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Molecules (Basel, Switzerland) (15.10.2019)
Published in Molecules (Basel, Switzerland) (15.10.2019)
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Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1
Il’ina, Irina V., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Sidorenko, Alexander Yu, Li-Zhulanov, Nikolay S., Korchagina, Dina V., Chand, Raina, Ayine-Tora, Daniel M., Chepanova, Arina A., Zakharova, Olga D., Ilina, Ekaterina S., Reynisson, Jóhannes, Malakhova, Anastasia A., Medvedev, Sergey P., Zakian, Suren M., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Molecules (Basel, Switzerland) (31.07.2020)
Published in Molecules (Basel, Switzerland) (31.07.2020)
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Multifunctional human serum albumin-therapeutic nucleotide conjugate with redox and pH-sensitive drug release mechanism for cancer theranostics
Lisitskiy, Vladimir A., Khan, Hamda, Popova, Tatyana V., Chubarov, Alexey S., Zakharova, Olga D., Akulov, Andrey E., Shevelev, Oleg B., Zavjalov, Evgenii L., Koptyug, Igor V., Moshkin, Mikhail P., Silnikov, Vladimir N., Ahmad, Saheem, Godovikova, Tatyana S.
Published in Bioorganic & medicinal chemistry letters (15.08.2017)
Published in Bioorganic & medicinal chemistry letters (15.08.2017)
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HIV-1 integrase-hydrolyzing IgM antibodies from sera of HIV-infected patients
Baranova, Svetlana V., Buneva, Valentina N., Kharitonova, Marina A., Sizyakina, Ludmila P., Calmels, Christina, Andreola, Marie-Line, Parissi, Vincent, Zakharova, Olga D., Nevinsky, Georgy A.
Published in International immunology (01.08.2010)
Published in International immunology (01.08.2010)
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Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors
Ponomarev, Konstantin Yu, Suslov, Evgeniy V., Zakharenko, Alexandra L., Zakharova, Olga D., Rogachev, Artem D., Korchagina, Dina V., Zafar, Ayesha, Reynisson, Jóhannes, Nefedov, Andrey A., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Bioorganic chemistry (01.02.2018)
Published in Bioorganic chemistry (01.02.2018)
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Antioxidant and antitumor activity of trolox, trolox succinate, and α-tocopheryl succinate conjugates with nitroxides
Zakharova, Ol’ga D., Frolova, Tat’yana S., Yushkova, Yuliya V., Chernyak, Elena I., Pokrovsky, Andrei G., Pokrovsky, Mikhail A., Morozov, Sergei V., Sinitsina, Ol’ga I., Grigor’ev, Igor A., Nevinsky, Georgy A.
Published in European journal of medicinal chemistry (21.10.2016)
Published in European journal of medicinal chemistry (21.10.2016)
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An effective two-step synthesis, fluorescent properties, antioxidant activity and cytotoxicity evaluation of benzene-fluorinated 2,2-dimethyl-2,3-dihydro-1H-quinolin-4-ones
Politanskaya, Larisa V., Chuikov, Igor P., Tretyakov, Evgeny V., Shteingarts, Vitalij D., Ovchinnikova, Ludmila P., Zakharova, Olga D., Nevinsky, Georgy A.
Published in Journal of fluorine chemistry (01.10.2015)
Published in Journal of fluorine chemistry (01.10.2015)
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Protein modification by thiolactone homocysteine chemistry: a multifunctionalized human serum albumin theranostic
Popova, Tatyana V, Krumkacheva, Olesya A, Burmakova, Anna S, Spitsyna, Anna S, Zakharova, Olga D, Lisitskiy, Vladimir A, Kirilyuk, Igor A, Silnikov, Vladimir N, Bowman, Michael K, Bagryanskaya, Elena G, Godovikova, Tatyana S
Published in MedChemComm (02.04.2020)
Published in MedChemComm (02.04.2020)
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Design of protein homocystamides with enhanced tumor uptake properties for (19)F magnetic resonance imaging
Chubarov, Alexey S, Zakharova, Olga D, Koval, Olga A, Romaschenko, Alexander V, Akulov, Andrey E, Zavjalov, Evgenii L, Razumov, Ivan A, Koptyug, Igor V, Knorre, Dmitry G, Godovikova, Tatyana S
Published in Bioorganic & medicinal chemistry (01.11.2015)
Published in Bioorganic & medicinal chemistry (01.11.2015)
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