C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway
Kataria, Nalin, Martinez, Chloe-Anne, Kerr, Bernadette, Zaiter, Samantha S, Morgan, Monica, McAlpine, Shelli R, Cook, Kristina M
Published in Cellular physiology and biochemistry (2019)
Published in Cellular physiology and biochemistry (2019)
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Hsp90 Mediates Membrane Deformation and Exosome Release
Lauwers, Elsa, Wang, Yu-Chun, Gallardo, Rodrigo, Van der Kant, Rob, Michiels, Emiel, Swerts, Jef, Baatsen, Pieter, Zaiter, Samantha S., McAlpine, Shelli R., Gounko, Natalia V., Rousseau, Frederic, Schymkowitz, Joost, Verstreken, Patrik
Published in Molecular cell (06.09.2018)
Published in Molecular cell (06.09.2018)
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Designing de Novo Small Molecules That Control Heat Shock Protein 70 (Hsp70) and Heat Shock Organizing Protein (HOP) within the Chaperone Protein-Folding Machinery
Zaiter, Samantha S, Huo, Yuantao, Tiew, Fong Y, Gestwicki, Jason E, McAlpine, Shelli R
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Synthesis and Structure–Activity Relationships of Inhibitors That Target the C‑Terminal MEEVD on Heat Shock Protein 90
Rahimi, Marwa N, Buckton, Laura K, Zaiter, Samantha S, Kho, Jessica, Chan, Vickie, Guo, Aldwin, Konesan, Jenane, Kwon, SuHyeon, Lam, Lok K. O, Lawler, Michael F, Leong, Michael, Moldovan, Gabriel D, Neale, David A, Thornton, Gillian, McAlpine, Shelli R
Published in ACS medicinal chemistry letters (08.02.2018)
Published in ACS medicinal chemistry letters (08.02.2018)
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Hitting a Moving Target: How Does an N-Methyl Group Impact Biological Activity?
Koay, Yen Chin, Richardson, Nicole L., Zaiter, Samantha S., Kho, Jessica, Nguyen, Sheena Y., Tran, Daniel H., Lee, Ka Wai, Buckton, Laura K., McAlpine, Shelli R.
Published in ChemMedChem (19.04.2016)
Published in ChemMedChem (19.04.2016)
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