ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response
Adeyemo, Adebowale A., Zaghloul, Norann A., Chen, Guanjie, Doumatey, Ayo P., Leitch, Carmen C., Hostelley, Timothy L., Nesmith, Jessica E., Zhou, Jie, Bentley, Amy R., Shriner, Daniel, Fasanmade, Olufemi, Okafor, Godfrey, Eghan, Benjamin, Agyenim-Boateng, Kofi, Chandrasekharappa, Settara, Adeleye, Jokotade, Balogun, William, Owusu, Samuel, Amoah, Albert, Acheampong, Joseph, Johnson, Thomas, Oli, Johnnie, Adebamowo, Clement, Collins, Francis, Dunston, Georgia, Rotimi, Charles N.
Published in Nature communications (19.07.2019)
Published in Nature communications (19.07.2019)
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Journal Article
RFX transcription factors are essential for hearing in mice
Elkon, Ran, Milon, Beatrice, Morrison, Laura, Shah, Manan, Vijayakumar, Sarath, Racherla, Manoj, Leitch, Carmen C., Silipino, Lorna, Hadi, Shadan, Weiss-Gayet, Michèle, Barras, Emmanuèle, Schmid, Christoph D., Ait-Lounis, Aouatef, Barnes, Ashley, Song, Yang, Eisenman, David J., Eliyahu, Efrat, Frolenkov, Gregory I., Strome, Scott E., Durand, Bénédicte, Zaghloul, Norann A., Jones, Sherri M., Reith, Walter, Hertzano, Ronna
Published in Nature communications (15.10.2015)
Published in Nature communications (15.10.2015)
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Journal Article
The emerging face of primary cilia
Zaghloul, Norann A., Brugmann, Samantha A.
Published in Genesis (New York, N.Y. : 2000) (01.04.2011)
Published in Genesis (New York, N.Y. : 2000) (01.04.2011)
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Journal Article
Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators
Liu, Yangfan P, Tsai, I-Chun, Morleo, Manuela, Oh, Edwin C, Leitch, Carmen C, Massa, Filomena, Lee, Byung-Hoon, Parker, David S, Finley, Daniel, Zaghloul, Norann A, Franco, Brunella, Katsanis, Nicholas
Published in The Journal of clinical investigation (01.05.2014)
Published in The Journal of clinical investigation (01.05.2014)
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Journal Article
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
Liu, Yangfan, Gerdes, Jantje M, Zaghloul, Norann A, Fisher, Shannon, Badano, Jose L, Katsanis, Nicholas, Beales, Philip L, Leitch, Carmen C, Beachy, Philip A, Kato, Masaki, DeMartino, George N, Lawson, Shaneka S
Published in Nature genetics (01.11.2007)
Published in Nature genetics (01.11.2007)
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Journal Article
Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome
Zaghloul, Norann A, Liu, Yangjian, Gerdes, Jantje M, Gascue, Cecilia, Oh, Edwin C, Leitch, Carmen C, Bromberg, Yana, Binkley, Jonathan, Leibel, Rudolph L, Sidow, Arend, Badano, Jose L, Katsanis, Nicholas
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2010)
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Journal Article
Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio
Edie, Sarah, Zaghloul, Norann A, Leitch, Carmen C, Klinedinst, Donna K, Lebron, Janette, Thole, Joey F, McCallion, Andrew S, Katsanis, Nicholas, Reeves, Roger H
Published in G3 : genes - genomes - genetics (01.07.2018)
Published in G3 : genes - genomes - genetics (01.07.2018)
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Journal Article
Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S]
O'Hare, Elizabeth A., Wang, Xiaochun, Montasser, May E., Chang, Yen-Pei C., Mitchell, Braxton D., Zaghloul, Norann A.
Published in Journal of lipid research (01.11.2014)
Published in Journal of lipid research (01.11.2014)
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Journal Article
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
Khan, Shahid Y., Vasanth, Shivakumar, Kabir, Firoz, Gottsch, John D., Khan, Arif O., Chaerkady, Raghothama, Lee, Mei-Chong W., Leitch, Carmen C., Ma, Zhiwei, Laux, Julie, Villasmil, Rafael, Khan, Shaheen N., Riazuddin, Sheikh, Akram, Javed, Cole, Robert N., Talbot, C. Conover, Pourmand, Nader, Zaghloul, Norann A., Hejtmancik, J. Fielding, Riazuddin, S. Amer
Published in Nature communications (06.04.2016)
Published in Nature communications (06.04.2016)
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Journal Article
Identification of a Novel BBS Gene ( BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome
Stoetzel, Corinne, Muller, Jean, Laurier, Virginie, Davis, Erica E., Zaghloul, Norann A., Vicaire, Serge, Jacquelin, Cécile, Plewniak, Frédéric, Leitch, Carmen C., Sarda, Pierre, Hamel, Christian, de Ravel, Thomy J.L., Lewis, Richard Alan, Friederich, Evelyne, Thibault, Christelle, Danse, Jean-Marc, Verloes, Alain, Bonneau, Dominique, Katsanis, Nicholas, Poch, Olivier, Mandel, Jean-Louis, Dollfus, Hélène
Published in American journal of human genetics (01.01.2007)
Published in American journal of human genetics (01.01.2007)
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Journal Article
Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy
Zaghloul, Norann A, Katsanis, Nicholas
Published in The Journal of clinical investigation (01.03.2009)
Published in The Journal of clinical investigation (01.03.2009)
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Journal Article
Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems
Hostelley, Timothy L, Nesmith, Jessica E, Larkin, Emily, Jones, Amanda, Boyes, Daniel, Leitch, Carmen C, Fontaine, Magali, Zaghloul, Norann A
Published in Biology open (15.06.2021)
Published in Biology open (15.06.2021)
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Journal Article
Epistasis between RET and BBS mutations modulates enteric innervation and causes syndromic Hirschsprung disease
de Pontual, Loïc, Zaghloul, Norann A, Thomas, Sophie, Davis, Erica E, Mcgaughey, David M, Dollfus, Hélène, Baumann, Clarisse, Bessling, Seneca L, Babarit, Candice, Pelet, Anna, Gascue, Cecilia, Beales, Philip, Munnich, Arnold, Lyonnet, Stanislas, Etchevers, Heather, Attie-Bitach, Tania, Badano, Jose L, McCallion, Andrew S, Katsanis, Nicholas, Amiel, Jeanne
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2009)
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Journal Article
An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes
Li, Chunmei, Inglis, Peter N, Leitch, Carmen C, Efimenko, Evgeni, Zaghloul, Norann A, Mok, Calvin A, Davis, Erica E, Bialas, Nathan J, Healey, Michael P, Héon, Elise, Zhen, Mei, Swoboda, Peter, Katsanis, Nicholas, Leroux, Michel R
Published in PLoS genetics (01.03.2008)
Published in PLoS genetics (01.03.2008)
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Journal Article
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry
Tsiokas, Leonidas, Oh, Edwin C, Kim, Sehyun, Obara, Tomoko, Zaghloul, Norann A, Katsanis, Nicholas, Rankin, Susannah, Bubenshchikova, Ekaterina
Published in Nature cell biology (01.04.2011)
Published in Nature cell biology (01.04.2011)
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Journal Article
Basal body proteins regulate Notch signaling through endosomal trafficking
Leitch, Carmen C, Lodh, Sukanya, Prieto-Echagüe, Victoria, Badano, Jose L, Zaghloul, Norann A
Published in Journal of cell science (01.06.2014)
Published in Journal of cell science (01.06.2014)
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Journal Article