Next-generation Fc receptor–targeting biologics for autoimmune diseases
Zuercher, Adrian W., Spirig, Rolf, Baz Morelli, Adriana, Rowe, Tony, Käsermann, Fabian
Published in Autoimmunity reviews (01.10.2019)
Published in Autoimmunity reviews (01.10.2019)
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Journal Article
Analysis and functional consequences of increased Fab-sialylation of intravenous immunoglobulin (IVIG) after lectin fractionation
Käsermann, Fabian, Boerema, David J, Rüegsegger, Monika, Hofmann, Andreas, Wymann, Sandra, Zuercher, Adrian W, Miescher, Sylvia
Published in PloS one (04.06.2012)
Published in PloS one (04.06.2012)
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Journal Article
Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils
Campbell, Ian K, Miescher, Sylvia, Branch, Donald R, Mott, Patrick J, Lazarus, Alan H, Han, Dongji, Maraskovsky, Eugene, Zuercher, Adrian W, Neschadim, Anton, Leontyev, Danila, McKenzie, Brent S, Käsermann, Fabian
Published in The Journal of immunology (1950) (01.06.2014)
Published in The Journal of immunology (1950) (01.06.2014)
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Journal Article
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Vonarburg, Cédric, Loetscher, Marius, Spycher, Martin O, Kropf, Alain, Illi, Marlies, Salmon, Sharon, Roberts, Sean, Steinfuehrer, Karin, Campbell, Ian, Koernig, Sandra, Bain, Joseph, Edler, Monika, Baumann, Ulrich, Miescher, Sylvia, Metzger, Dennis W, Schaub, Alexander, Käsermann, Fabian, Zuercher, Adrian W
Published in Respiratory research (22.05.2019)
Published in Respiratory research (22.05.2019)
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Journal Article
Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer
Lewis, Bonnie J B, Ville, Jade, Blacquiere, Megan, Cen, Selena, Spirig, Rolf, Zuercher, Adrian W, Käsermann, Fabian, Branch, Donald R
Published in BMC immunology (04.12.2019)
Published in BMC immunology (04.12.2019)
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Journal Article
Preclinical In Vitro and In Vivo Characterization of the Fully Human Monoclonal IgM Antibody KBPA101 Specific for Pseudomonas aeruginosa Serotype IATS-O11
HORN, Michael P, ZUERCHER, Adrian W, IMBODEN, Martin A, RUDOLF, Michael P, LAZAR, Hedvika, HONG WU, HOIBY, Niels, FAS, Stefanie C, LANG, Alois B
Published in Antimicrobial Agents and Chemotherapy (01.06.2010)
Published in Antimicrobial Agents and Chemotherapy (01.06.2010)
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Journal Article
Pharmacokinetics and Safety Profile of the Human Anti-Pseudomonas aeruginosa Serotype O11 Immunoglobulin M Monoclonal Antibody KBPA-101 in Healthy Volunteers
LAZAR, Hedvika, HORN, Michael P, ZUERCHER, Adrian W, IMBODEN, Martin A, DURRER, Peter, SEIBERLING, Michael, POKORNY, Rolf, HAMMER, Christophe, LANG, Alois B
Published in Antimicrobial Agents and Chemotherapy (01.08.2009)
Published in Antimicrobial Agents and Chemotherapy (01.08.2009)
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Journal Article
IVIG in autoimmune disease – Potential next generation biologics
Zuercher, Adrian W, Spirig, Rolf, Morelli, Adriana Baz, Käsermann, Fabian
Published in Autoimmunity reviews (01.08.2016)
Published in Autoimmunity reviews (01.08.2016)
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Journal Article
Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner
Willis, Emily F., Gillespie, Ellen R., Guse, Kirsten, Zuercher, Adrian W., Käsermann, Fabian, Ruitenberg, Marc J., Vukovic, Jana
Published in Brain, behavior, and immunity (01.03.2023)
Published in Brain, behavior, and immunity (01.03.2023)
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Journal Article
Reversal of Arthritis by Human Monomeric IgA Through the Receptor‐Mediated SH2 Domain–Containing Phosphatase 1 Inhibitory Pathway
Rossato, Elisabetta, Ben Mkaddem, Sanae, Kanamaru, Yutaka, Hurtado‐Nedelec, Margarita, Hayem, Gilles, Descatoire, Véronique, Vonarburg, Cédric, Miescher, Sylvia, Zuercher, Adrian W., Monteiro, Renato C.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2015)
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Journal Article
Human Plasma-derived Polymeric IgA and IgM Antibodies Associate with Secretory Component to Yield Biologically Active Secretory-like Antibodies
Longet, Stéphanie, Miled, Sarah, Lötscher, Marius, Miescher, Sylvia M., Zuercher, Adrian W., Corthésy, Blaise
Published in The Journal of biological chemistry (08.02.2013)
Published in The Journal of biological chemistry (08.02.2013)
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Journal Article
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs
Spirig, Rolf, Campbell, Ian K, Koernig, Sandra, Chen, Chao-Guang, Lewis, Bonnie J B, Butcher, Rebecca, Muir, Ineke, Taylor, Shirley, Chia, Jenny, Leong, David, Simmonds, Jason, Scotney, Pierre, Schmidt, Peter, Fabri, Louis, Hofmann, Andreas, Jordi, Monika, Spycher, Martin O, Cattepoel, Susann, Brasseit, Jennifer, Panousis, Con, Rowe, Tony, Branch, Donald R, Baz Morelli, Adriana, Käsermann, Fabian, Zuercher, Adrian W
Published in The Journal of immunology (1950) (15.04.2018)
Published in The Journal of immunology (1950) (15.04.2018)
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Journal Article
A novel soluble complement receptor 1 fragment with enhanced therapeutic potential
Wymann, Sandra, Dai, Yun, Nair, Anup G., Cao, Helen, Powers, Glenn A., Schnell, Anna, Martin-Roussety, Genevieve, Leong, David, Simmonds, Jason, Lieu, Kim G., de Souza, Mitchell J., Mischnik, Marcel, Taylor, Shirley, Ow, Saw Yen, Spycher, Martin, Butcher, Rebecca E., Pearse, Martin, Zuercher, Adrian W., Baz Morelli, Adriana, Panousis, Con, Wilson, Michael J., Rowe, Tony, Hardy, Matthew P.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment
Wehrli, Marc, Cortinas-Elizondo, Fabiola, Hlushchuk, Ruslan, Daudel, Fritz, Villiger, Peter M, Miescher, Sylvia, Zuercher, Adrian W, Djonov, Valentin, Simon, Hans-Uwe, von Gunten, Stephan
Published in The Journal of immunology (1950) (01.12.2014)
Published in The Journal of immunology (1950) (01.12.2014)
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Journal Article
Treating murine inflammatory diseases with an anti-erythrocyte antibody
Crow, Andrew R, Kapur, Rick, Koernig, Sandra, Campbell, Ian K, Jen, Chao-Ching, Mott, Patrick J, Marjoram, Danielle, Khan, Ramsha, Kim, Michael, Brasseit, Jennifer, Cruz-Leal, Yoelys, Amash, Alaa, Kahlon, Simrat, Yougbare, Issaka, Ni, Heyu, Zuercher, Adrian W, Käsermann, Fabian, Semple, John W, Lazarus, Alan H
Published in Science translational medicine (21.08.2019)
Published in Science translational medicine (21.08.2019)
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Distinctive anti-allergy properties of two probiotic bacterial strains in a mouse model of allergic poly-sensitization
Schabussova, Irma, Hufnagl, Karin, Wild, Carmen, Nutten, Sophie, Zuercher, Adrian W, Mercenier, Annick, Wiedermann, Ursula
Published in Vaccine (24.02.2011)
Published in Vaccine (24.02.2011)
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Journal Article
Dietary supplementation with Bifidobacterium lactis NCC2818 from weaning reduces local immunoglobulin production in lymphoid-associated tissues but increases systemic antibodies in healthy neonates
Lewis, Marie C., Patel, Dilip V., Fowler, Jenni, Duncker, Swantje, Zuercher, Adrian W., Mercenier, Annick, Bailey, Mick
Published in British journal of nutrition (14.10.2013)
Published in British journal of nutrition (14.10.2013)
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Journal Article
Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model
Koernig, Sandra, Campbell, Ian K., Mackenzie-Kludas, Charley, Schaub, Alexander, Loetscher, Marius, Ching Ng, Wy, Zehnder, Roland, Pelczar, Pawel, Sanli, Ildem, Alhamdoosh, Monther, Ng, Milica, Brown, Lorena E., Käsermann, Fabian, Vonarburg, Cédric, Zuercher, Adrian W.
Published in Mucosal immunology (01.07.2019)
Published in Mucosal immunology (01.07.2019)
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Journal Article
Characterization of Candidate Anti-Allergic Probiotic Strains in a Model of Th2-Skewed Human Peripheral Blood Mononuclear Cells
Holvoet, Sébastien, Zuercher, Adrian W., Julien-Javaux, Françoise, Perrot, Marie, Mercenier, Annick
Published in International archives of allergy and immunology (01.05.2013)
Published in International archives of allergy and immunology (01.05.2013)
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