A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity
Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis
Published in Nature communications (15.11.2018)
Published in Nature communications (15.11.2018)
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Journal Article
T-SIGn tumor reengineering therapy and CAR T cells synergize in combination therapy to clear human lung tumor xenografts and lung metastases in NSG mice
Sonzogni, Olmo, Zak, Daniel E., Sasso, Maria Stella, Lear, Rochelle, Muntzer, Alice, Zonca, Manuela, West, Katy, Champion, Brian R., Rottman, James B.
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Journal Article
NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses
Di Pilato, Mauro, Mejías-Pérez, Ernesto, Zonca, Manuela, Perdiguero, Beatriz, Gómez, Carmen Elena, Trakala, Marianna, Nieto, Jacobo, Nájera, José Luis, Sorzano, Carlos Oscar S., Combadière, Christophe, Pantaleo, Giuseppe, Planelles, Lourdes, Esteban, Mariano
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
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Journal Article
An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity
Compte, Marta, Harwood, Seandean L, Erce-Llamazares, Ainhoa, Tapia-Galisteo, Antonio, Romero, Eduardo, Ferrer, Irene, Garrido-Martin, Eva M, Enguita, Ana B, Ochoa, Maria C, Blanco, Belén, Oteo, Marta, Merino, Nekane, Nehme-Álvarez, Daniel, Hangiu, Oana, Domínguez-Alonso, Carmen, Zonca, Manuela, Ramírez-Fernández, Angel, Blanco, Francisco J, Morcillo, Miguel A, Muñoz, Ines G, Melero, Ignacio, Rodriguez-Peralto, José L, Paz-Ares, Luis, Sanz, Laura, Alvarez-Vallina, Luis
Published in Clinical cancer research (01.06.2021)
Published in Clinical cancer research (01.06.2021)
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Journal Article
High-resolution live-cell imaging reveals novel cyclin A2 degradation foci involving autophagy
Loukil, Abdelhalim, Zonca, Manuela, Rebouissou, Cosette, Baldin, Véronique, Coux, Olivier, Biard-Piechaczyk, Martine, Blanchard, Jean-Marie, Peter, Marion
Published in Journal of cell science (15.05.2014)
Published in Journal of cell science (15.05.2014)
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Abstract 5013: NG-641: An oncolytic T-SIGn virus targeting cancer-associated fibroblasts in the stromal microenvironment of human carcinomas
Champion, Brian R., Besneux, Matthieu, Patsalidou, Marilena, Silva, Ana, Zonca, Manuela, Marino, Nalini, Genova, Gianfranco di, Illingworth, Sam, Fedele, Stefania, Slater, Lorna, Lilley, Fred, Plumb, Darren, West, Katy, Cockle, Paul, Brown, Alice
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
208 T-SIGn vector-mediated antigen “spray painting” and tumor microenvironment (TME) reprogramming to enable CAR-T cell targeting of solid tumors
Sasso, Maria Stella, Bergin, Rachel, Zonca, Manuela, Vainiute, Eva, Jang, Tae Hyun, Oubihi, Zahra, Snowden, Meg, Muntzer, Alice, Cerqueira, Carla, Lear, Rochelle, West, Katy, Champion, Brian
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Abstract 5746: Flexible tumor-specific cytokine and antigen delivery through the T-SIGn vector platform enables effective CAR-T cell therapy against solid tumors
Sasso, Maria Stella, Bergin, Rachel, Lear, Rochelle, Plumb, Darren, Zonca, Manuela, Vainiute, Eva, Snowden, Meg, Jang, Tae Hyun, Muntzer, Alice, Cerqueira, Carla C., West, Katy, Bucktrout, Samantha, Champion, Brian R.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 2740: Safe and effective delivery of antibody fragments to the solid tumor microenvironment
Bergin, Rachel, Pelletier, Amandine, Zonca, Manuela, Muntzer, Alice, Snowden, Meg, Hardy, Samuel, Cerqueira, Carla, Hyun-Jang, Tae, Lear, Rochelle, Fujinobu, Masumi, Sasso, Maria Stella, Bucktrout, Samantha, Champion, Brian R.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
APRIL promotes breast tumor growth and metastasis and is associated with aggressive basal breast cancer
García-Castro, Araceli, Zonca, Manuela, Florindo-Pinheiro, Douglas, Carvalho-Pinto, Carla E, Cordero, Alex, Gutiérrez del Fernando, Burgo, García-Grande, Aránzazu, Mañes, Santos, Hahne, Michael, González-Suárez, Eva, Planelles, Lourdes
Published in Carcinogenesis (New York) (01.05.2015)
Published in Carcinogenesis (New York) (01.05.2015)
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Journal Article
NF[kappa]B activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses
DiPilato, Mauro, Mejías-Pérez, Ernesto, Zonca, Manuela, Perdiguero, Beatriz, Gómez, Carmen Elena, Trakala, Marianna, Nieto, Jacobo, Nájera, José Luis, Sorzano, Carlos Oscar S, Combadière, Christophe, Pantaleo, Giuseppe, Planelles, Lourdes, Esteban, Mariano
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
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Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Journal Article
Distinct Trafficking of Cell Surface and Endosomal TIM‐1 to the Immune Synapse
Echbarthi, Meriem, Zonca, Manuela, Mellwig, Rachel, Schwab, Yannick, Kaplan, Gerardo, DeKruyff, Rosemarie H., Roda‐Navarro, Pedro, Casasnovas, Jose M.
Published in Traffic (Copenhagen, Denmark) (01.11.2015)
Published in Traffic (Copenhagen, Denmark) (01.11.2015)
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Journal Article
APRIL and BAFF Proteins Increase Proliferation of Human Adipose-Derived Stem Cells Through Activation of Erk1/2 MAP Kinase
Zonca, Manuela, Mancheño-Corvo, Pablo, DelaRosa, Olga, Mañes, Santos, Büscher, Dirk, Lombardo, Eleuterio, Planelles, Lourdes
Published in Tissue engineering. Part A (01.04.2012)
Published in Tissue engineering. Part A (01.04.2012)
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