Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity
Jayasuriya, Hiranthi, Herath, Kithsiri B., Zhang, Chaowei, Zink, Deborah L., Basilio, Angela, Genilloud, Olga, Diez, Maria Teresa, Vicente, Francisca, Gonzalez, Ignacio, Salazar, Oscar, Pelaez, Fernando, Cummings, Richard, Ha, Sookhee, Wang, Jun, Singh, Sheo B.
Published in Angewandte Chemie (International ed.) (01.01.2007)
Published in Angewandte Chemie (International ed.) (01.01.2007)
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Journal Article
Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy
Singh, Sheo B, Jayasuriya, Hiranthi, Ondeyka, John G, Herath, Kithsiri B, Zhang, Chaowei, Zink, Deborah L, Tsou, Nancy N, Ball, Richard G, Basilio, Angela, Genilloud, Olga, Diez, Maria Teresa, Vicente, Francisca, Pelaez, Fernando, Young, Katherine, Wang, Jun
Published in Journal of the American Chemical Society (13.09.2006)
Published in Journal of the American Chemical Society (13.09.2006)
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Journal Article
Platensimycin and Platencin Congeners from Streptomyces platensis
Zhang, Chaowei, Ondeyka, John, Herath, Kithsiri, Jayasuriya, Hiranthi, Guan, Ziqiang, Zink, Deborah L, Dietrich, Lisa, Burgess, Bruce, Ha, Sookhee N, Wang, Jun, Singh, Sheo B
Published in Journal of natural products (Washington, D.C.) (25.03.2011)
Published in Journal of natural products (Washington, D.C.) (25.03.2011)
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Journal Article
Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin
Ondeyka, John G, Smith, Scott K, Zink, Deborah L, Vicente, Francisca, Basilio, Angela, Bills, Gerald F, Polishook, Jon D, Garlisi, Charles, Mcguinness, Debra, Smith, Elizabeth, Qiu, Hongchen, Gill, Charles J, Donald, Robert GK, Phillips, John W, Goetz, Michael A, Singh, Sheo B
Published in Journal of antibiotics (01.07.2014)
Published in Journal of antibiotics (01.07.2014)
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Journal Article
Isolation, Structure Elucidation, and Biological Activity of Altersolanol P Using Staphylococcus aureus Fitness Test Based Genome-Wide Screening
Ondeyka, John, Buevich, Alexei V, Williamson, R. Thomas, Zink, Deborah L, Polishook, Jon D, Occi, James, Vicente, Francisca, Basilio, Angela, Bills, Gerald F, Donald, Robert G. K, Phillips, John W, Goetz, Michael A, Singh, Sheo B
Published in Journal of natural products (Washington, D.C.) (28.03.2014)
Published in Journal of natural products (Washington, D.C.) (28.03.2014)
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Journal Article
Isolation, Structure Elucidation, and Antibacterial Activity of Methiosetin, a Tetramic Acid from a Tropical Sooty Mold (Capnodium sp.)
Herath, Kithsiri, Jayasuriya, Hiranthi, Zink, Deborah L, Sigmund, Jan, Vicente, Francisca, de la Cruz, Mercedes, Basilio, Angela, Bills, Gerald F, Polishook, Jon D, Donald, Robert, Phillips, John, Goetz, Michael, Singh, Sheo B
Published in Journal of natural products (Washington, D.C.) (23.03.2012)
Published in Journal of natural products (Washington, D.C.) (23.03.2012)
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Journal Article
Isolation, Structure, and Antibacterial Activities of Lucensimycins D−G, Discovered from Streptomyces lucensis MA7349 Using an Antisense Strategy
Singh, Sheo B, Zink, Deborah L, Dorso, Karen, Motyl, Mary, Salazar, Oscar, Basilio, Angela, Vicente, Francisca, Byrne, Kevin M, Ha, Sookhee, Genilloud, Olga
Published in Journal of natural products (Washington, D.C.) (27.03.2009)
Published in Journal of natural products (Washington, D.C.) (27.03.2009)
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Journal Article
Occurrence, distribution, dereplication and efficient discovery of thiazolyl peptides by sensitive-resistant pair screening
Singh, Sheo B, Zhang, Chaowei, Zink, Deborah L, Herath, Kithsiri, Ondeyka, John, Masurekar, Prakash, Jayasuriya, Hiranthi, Goetz, Michael A, Tormo, Jose Rubén, Vicente, Francisca, Martín, Jesús, González, Ignacio, Genilloud, Olga
Published in Journal of antibiotics (01.10.2013)
Published in Journal of antibiotics (01.10.2013)
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Journal Article
Anthelmintic constituents of Clonostachys candelabrum
Ayers, Sloan, Zink, Deborah L, Mohn, Kenneth, Powell, Joanne S, Brown, Christine M, Bills, Gerald, Grund, Alan, Thompson, Donald, Singh, Sheo B
Published in Journal of antibiotics (01.03.2010)
Published in Journal of antibiotics (01.03.2010)
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Journal Article
Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis
Singh, Sheo B, Ondeyka, John G, Herath, Kithsiri B, Zhang, Chaowei, Jayasuriya, Hiranthi, Zink, Deborah L, Parthasarathy, Gopalakrishnan, Becker, Joseph W, Wang, Jun, Soisson, Stephen M
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Journal Article
Discovery of okilactomycin and congeners from Streptomyces scabrisporus by antisense differential sensitivity assay targeting ribosomal protein S4
Zhang, Chaowei, Ondeyka, John G, Zink, Deborah L, Basilio, Angela, Vicente, Francisca, Salazar, Oscar, Genilloud, Olga, Dorso, Karen, Motyl, Mary, Byrne, Kevin, Singh, Sheo B
Published in Journal of antibiotics (01.02.2009)
Published in Journal of antibiotics (01.02.2009)
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Journal Article
Discovery and antibacterial activity of lucensimycin C from Streptomyces lucensis
Singh, Sheo B., Zink, Deborah L., Herath, Kithsiri B., Salazar, Oscar, Genilloud, Olga
Published in Tetrahedron letters (01.04.2008)
Published in Tetrahedron letters (01.04.2008)
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Journal Article
Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites
SINGH, Sheo B, JAYASURIYA, Hiranthi, FELOCK, Peter J, HAZUDA, Daria J, DEWEY, Raymond, POLISHOOK, Jon D, DOMBROWSKI, Anne W, ZINK, Deborah L, ZIQIANG GUAN, COLLADO, Javier, PLATAS, Gonzalo, PELAEZ, Fernando
Published in Journal of industrial microbiology & biotechnology (01.12.2003)
Published in Journal of industrial microbiology & biotechnology (01.12.2003)
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Journal Article
Discovery of Lucensimycins A and B from Streptomyces lucensis MA7349 Using an Antisense Strategy
Singh, Sheo B, Zink, Deborah L, Huber, Joanne, Genilloud, Olga, Salazar, Oscar, Diez, M. Teresa, Basilio, Angela, Vicente, Francisca, Byrne, Kevin M
Published in Organic letters (23.11.2006)
Published in Organic letters (23.11.2006)
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Journal Article
From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9
Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, Alison M., Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.
Published in Cell chemical biology (16.01.2020)
Published in Cell chemical biology (16.01.2020)
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Journal Article
Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling
Goetz, Michael A, Zhang, Chaowei, Zink, Deborah L, Arocho, Marta, Vicente, Francisca, Bills, Gerald F, Polishook, Jon, Dorso, Karen, Onishi, Russell, Gill, Charles, Hickey, Emily, Lee, Suzy, Ball, Richard, Skwish, Stephen, Donald, Robert G K, Phillips, John W, Singh, Sheo B
Published in Journal of antibiotics (01.08.2010)
Published in Journal of antibiotics (01.08.2010)
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Journal Article
Isolation and structure elucidation of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa
Jayasuriya, Hiranthi, Herath, Kithsiri, Ondeyka, John G, Zhang, Chaowei, Zink, Deborah L, Brower, Mark, Gailliot, Francis P, Greene, Joyce, Birdsall, Gwyneth, Venugopal, Jayashree, Ushio, Misti, Burgess, Bruce, Russotti, Greg, Walker, Andre, Hesse, Michelle, Seeley, Anna, Junker, Beth, Connors, Neal, Salazar, Oscar, Genilloud, Olga, Liu, Kun, Masurekar, Prakash, Barrett, John F, Singh, Sheo B
Published in Journal of antibiotics (01.09.2007)
Published in Journal of antibiotics (01.09.2007)
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Journal Article
Anthelmintic Macrolactams from Nonomuraea turkmeniaca MA7381
Ayers, Sloan, Zink, Deborah L, Powell, Joanne Staats, Brown, Christine M, Grund, Alan, Genilloud, Olga, Salazar, Oscar, Thompson, Donald, Singh, Sheo B
Published in Journal of antibiotics (01.02.2008)
Published in Journal of antibiotics (01.02.2008)
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Journal Article
Nodulisporic Acids D−F: Structure, Biological Activities, and Biogenetic Relationships
Singh, Sheo B, Ondeyka, John G, Jayasuriya, Hiranthi, Zink, Deborah L, Ha, Sookhee N, Dahl-Roshak, Arlene, Greene, Joyce, Kim, Jennifer A, Smith, McHardy M, Shoop, Wesley, Tkacz, Jan S
Published in Journal of natural products (Washington, D.C.) (01.09.2004)
Published in Journal of natural products (Washington, D.C.) (01.09.2004)
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Journal Article
Isolation, Structure, and HIV-1 Integrase Inhibitory Activity of Xanthoviridicatin E and F, Two Novel Fungal Metabolites Produced by Penicillium chrysogenum
Singh, Sheo B., Zink, Deborah L., Guan, Ziqiang, Collado, Javier, Pelaez, Fernando, Felock, Peter J., Hazuda, Daria J.
Published in Helvetica chimica acta (01.10.2003)
Published in Helvetica chimica acta (01.10.2003)
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Journal Article