Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications
Zielonka, Jacek, Joseph, Joy, Sikora, Adam, Hardy, Micael, Ouari, Olivier, Vasquez-Vivar, Jeannette, Cheng, Gang, Lopez, Marcos, Kalyanaraman, Balaraman
Published in Chemical reviews (09.08.2017)
Published in Chemical reviews (09.08.2017)
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Journal Article
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis
Cheng, Gang, Zhang, Qi, Pan, Jing, Lee, Yongik, Ouari, Olivier, Hardy, Micael, Zielonka, Monika, Myers, Charles R., Zielonka, Jacek, Weh, Katherine, Chang, Andrew C., Chen, Guoan, Kresty, Laura, Kalyanaraman, Balaraman, You, Ming
Published in Nature communications (17.05.2019)
Published in Nature communications (17.05.2019)
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Journal Article
Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling
Kalyanaraman, Balaraman, Hardy, Micael, Podsiadly, Radoslaw, Cheng, Gang, Zielonka, Jacek
Published in Archives of biochemistry and biophysics (01.03.2017)
Published in Archives of biochemistry and biophysics (01.03.2017)
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Journal Article
Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies
Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Bennett, Brian, Zielonka, Jacek
Published in Redox biology (01.05.2018)
Published in Redox biology (01.05.2018)
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A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds
Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Lopez, Marcos, Joseph, Joy, Zielonka, Jacek, Dwinell, Michael B.
Published in Redox biology (01.04.2018)
Published in Redox biology (01.04.2018)
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Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon
Chowdhury, Anindya Roy, Zielonka, Jacek, Kalyanaraman, Balaraman, Hartley, Richard C., Murphy, Michael P., Avadhani, Narayan G.
Published in Redox biology (01.09.2020)
Published in Redox biology (01.09.2020)
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Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies
Dębski, Dawid, Smulik, Renata, Zielonka, Jacek, Michałowski, Bartosz, Jakubowska, Małgorzata, Dębowska, Karolina, Adamus, Jan, Marcinek, Andrzej, Kalyanaraman, Balaraman, Sikora, Adam
Published in Free radical biology & medicine (01.06.2016)
Published in Free radical biology & medicine (01.06.2016)
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HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes — The ultimate approach for intra- and extracellular superoxide detection
Kalyanaraman, Balaraman, Dranka, Brian P., Hardy, Micael, Michalski, Radoslaw, Zielonka, Jacek
Published in Biochimica et biophysica acta (01.02.2014)
Published in Biochimica et biophysica acta (01.02.2014)
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Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice
Langley, Monica, Ghosh, Anamitra, Charli, Adhithiya, Sarkar, Souvarish, Ay, Muhammet, Luo, Jie, Zielonka, Jacek, Brenza, Timothy, Bennett, Brian, Jin, Huajun, Ghaisas, Shivani, Schlichtmann, Benjamin, Kim, Dongsuk, Anantharam, Vellareddy, Kanthasamy, Arthi, Narasimhan, Balaji, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G
Published in Antioxidants & redox signaling (10.11.2017)
Published in Antioxidants & redox signaling (10.11.2017)
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Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future
Cheng, Gang, Zielonka, Monika, Dranka, Brian, Kumar, Suresh N., Myers, Charles R., Bennett, Brian, Garces, Alexander M., Dias Duarte Machado, Luiz Gabriel, Thiebaut, David, Ouari, Olivier, Hardy, Micael, Zielonka, Jacek, Kalyanaraman, Balaraman
Published in The Journal of biological chemistry (29.06.2018)
Published in The Journal of biological chemistry (29.06.2018)
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Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy
Mukhopadhyay, Partha, Horváth, Béla, Zsengellér, Zsuzsanna, Zielonka, Jacek, Tanchian, Galin, Holovac, Eileen, Kechrid, Malek, Patel, Vivek, Stillman, Isaac E., Parikh, Samir M., Joseph, Joy, Kalyanaraman, Balaraman, Pacher, Pál
Published in Free radical biology & medicine (15.01.2012)
Published in Free radical biology & medicine (15.01.2012)
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Novel Boronate Probe Based on 3-Benzothiazol-2-yl-7-hydroxy-chromen-2-one for the Detection of Peroxynitrite and Hypochlorite
Modrzejewska, Julia, Szala, Marcin, Grzelakowska, Aleksandra, Zakłos-Szyda, Małgorzata, Zielonka, Jacek, Podsiadły, Radosław
Published in Molecules (Basel, Switzerland) (30.09.2021)
Published in Molecules (Basel, Switzerland) (30.09.2021)
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Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death
Cheng, Gang, Zielonka, Jacek, McAllister, Donna M, Mackinnon, Jr, A Craig, Joseph, Joy, Dwinell, Michael B, Kalyanaraman, Balaraman
Published in BMC cancer (13.06.2013)
Published in BMC cancer (13.06.2013)
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Oxidation of ethidium-based probes by biological radicals: mechanism, kinetics and implications for the detection of superoxide
Michalski, Radosław, Thiebaut, David, Michałowski, Bartosz, Ayhan, Mehmet M., Hardy, Micael, Ouari, Olivier, Rostkowski, Michał, Smulik-Izydorczyk, Renata, Artelska, Angelika, Marcinek, Andrzej, Zielonka, Jacek, Kalyanaraman, Balaraman, Sikora, Adam
Published in Scientific reports (29.10.2020)
Published in Scientific reports (29.10.2020)
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