Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation
Zhu, Guangya, Xie, Jingjing, Kong, Wenna, Xie, Jingfei, Li, Yichen, Du, Lin, Zheng, Qiangang, Sun, Lin, Guan, Mingfeng, Li, Huan, Zhu, Tianxin, He, Hao, Liu, Zhenying, Xia, Xi, Kan, Chen, Tao, Youqi, Shen, Hong C., Li, Dan, Wang, Siying, Yu, Yongguo, Yu, Zhi-Hong, Zhang, Zhong-Yin, Liu, Cong, Zhu, Jidong
Published in Cell (15.10.2020)
Published in Cell (15.10.2020)
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Journal Article
Decoding the genomic landscape of chromatin-associated biomolecular condensates
Yu, Zhaowei, Wang, Qi, Zhang, Qichen, Tian, Yawen, Yan, Guo, Zhu, Jidong, Zhu, Guangya, Zhang, Yong
Published in Nature communications (13.08.2024)
Published in Nature communications (13.08.2024)
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Journal Article
Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia
Cao, Fang, Townsend, Elizabeth C., Karatas, Hacer, Xu, Jing, Li, Li, Lee, Shirley, Liu, Liu, Chen, Yong, Ouillette, Peter, Zhu, Jidong, Hess, Jay L., Atadja, Peter, Lei, Ming, Qin, Zhaohui S., Malek, Sami, Wang, Shaomeng, Dou, Yali
Published in Molecular cell (23.01.2014)
Published in Molecular cell (23.01.2014)
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Journal Article
Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity
Zhu, Guangya, Xie, Jingjing, Fu, Zhenzhen, Wang, Mingliang, Zhang, Qichen, He, Hao, Chen, Zijun, Guo, Xin, Zhu, Jidong
Published in Cell research (01.09.2021)
Published in Cell research (01.09.2021)
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Journal Article
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
Fei, Qi, Shang, Ke, Zhang, Jianhua, Chuai, Shannon, Kong, Desheng, Zhou, Tianlun, Fu, Shijun, Liang, Ying, Li, Chong, Chen, Zhi, Zhao, Yuan, Yu, Zhengtian, Huang, Zheng, Hu, Min, Ying, Haiyan, Chen, Zhui, Zhang, Yun, Xing, Feng, Zhu, Jidong, Xu, Haiyan, Zhao, Kehao, Lu, Chris, Atadja, Peter, Xiao, Zhi-Xiong, Li, En, Shou, Jianyong
Published in Nature communications (16.10.2015)
Published in Nature communications (16.10.2015)
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Journal Article
Radical-Induced Metal-Free Alkynylation of Aldehydes by Direct CH Activation
Liu, Xuesong, Yu, Linqian, Luo, Mupeng, Zhu, Jidong, Wei, Wanguo
Published in Chemistry : a European journal (08.06.2015)
Published in Chemistry : a European journal (08.06.2015)
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Journal Article
Protein O-GlcNAcylation coupled to Hippo signaling drives vascular dysfunction in diabetic retinopathy
Lei, Yi, Liu, Qiangyun, Chen, Binggui, Wu, Fangfang, Li, Yiming, Dong, Xue, Ma, Nina, Wu, Ziru, Zhu, Yanfang, Wang, Lu, Fu, Yuxin, Liu, Yuming, Song, Yinting, Du, Mei, Zhang, Heng, Zhu, Jidong, Lyons, Timothy J., Wang, Ting, Hu, Junhao, Xu, Heping, Chen, Mei, Yan, Hua, Wang, Xiaohong
Published in Nature communications (29.10.2024)
Published in Nature communications (29.10.2024)
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Journal Article
Modeling tumor development and metastasis using paired organoids derived from patients with colorectal cancer liver metastases
Li, He, Dai, Weixing, Xia, Xi, Wang, Renjie, Zhao, Jing, Han, Lingyu, Mo, Shaobo, Xiang, Wenqiang, Du, Lin, Zhu, Guangya, Xie, Jingjing, Yu, Jun, Liu, Nan, Huang, Mingzhu, Zhu, Jidong, Cai, Guoxiang
Published in Journal of hematology and oncology (03.09.2020)
Published in Journal of hematology and oncology (03.09.2020)
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Journal Article
Targeting androgen receptor phase separation to overcome antiandrogen resistance
Xie, Jingjing, He, Hao, Kong, Wenna, Li, Ziwen, Gao, Zhenting, Xie, Daoqing, Sun, Lin, Fan, Xiaofei, Jiang, Xiangqing, Zheng, Qiangang, Li, Guo, Zhu, Jidong, Zhu, Guangya
Published in Nature chemical biology (01.12.2022)
Published in Nature chemical biology (01.12.2022)
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Journal Article
Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment
Xie, Jingjing, Si, Xiaojia, Gu, Shoulai, Wang, Mingliang, Shen, Jian, Li, Haoyan, Shen, Jian, Li, Dan, Fang, Yanjia, Liu, Cong, Zhu, Jidong
Published in Journal of medicinal chemistry (28.12.2017)
Published in Journal of medicinal chemistry (28.12.2017)
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Journal Article
Screening inhibitors for blocking UHRF1-methylated DNA interaction with capillary electrophoresis
Lou, Chunli, Ye, Xiongzhen, Chen, Ge, Zhu, Jidong, Kang, Jingwu
Published in Journal of Chromatography A (11.01.2021)
Published in Journal of Chromatography A (11.01.2021)
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Journal Article
Radical-Induced Metal-Free Alkynylation of Aldehydes by Direct CH Activation
Liu, Xuesong, Yu, Linqian, Luo, Mupeng, Zhu, Jidong, Wei, Wanguo
Published in Chemistry : a European journal (08.06.2015)
Published in Chemistry : a European journal (08.06.2015)
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Journal Article
Phase separation ability and phosphatase activity of the SHP1-R360E mutant
Zhang, Qichen, Kong, Wenna, Zhu, Tianxin, Zhu, Guangya, Zhu, Jidong, Kong, Xiangyu, Du, Yiqi
Published in Biochemical and biophysical research communications (16.04.2022)
Published in Biochemical and biophysical research communications (16.04.2022)
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Journal Article
Inhibition of cIAP1 as a strategy for targeting c-MYC–driven oncogenic activity
Li, Haoyan, Fang, Yanjia, Niu, Chunyi, Cao, Hengyi, Mi, Ting, Zhu, Hong, Yuan, Junying, Zhu, Jidong
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2018)
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Journal Article
Effective approach to ureas through organocatalyzed one-pot process
Wang, Mingliang, Han, Jilai, Si, Xiaojia, Hu, Yimin, Zhu, Jidong, Sun, Xun
Published in Tetrahedron letters (25.04.2018)
Published in Tetrahedron letters (25.04.2018)
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Journal Article
Abstract 1475: Discovery of ETS-001, a highly potent allosteric SHP2 inhibitor to treat RTK/RAS-driven cancers
Xia, Xi, Du, Lin, Zhuge, Hao, Zheng, Qiangang, Cui, Wenqi, Zhu, Jidong, Li, Guo
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 326: Structural dynamics-based hit generation to disrupt YAP/TAZ-TEAD protein-protein interaction
Du, Lin, Liu, Jing, Zeng, Qinglong, Xu, Ming, Lu, Jiting, Zheng, Qiangang, Zhu, Jidong
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Phase separation underlies signaling activation of oncogenic NTRK fusions
Zhu, Tianxin, Xie, Jingjing, He, Hao, Li, Huan, Tang, Xianbin, Wang, Shuyang, Li, Ziwen, Tian, Yawen, Li, Lingyu, Zhu, Jidong, Zhu, Guangya
Published in Proceedings of the National Academy of Sciences - PNAS (17.10.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (17.10.2023)
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Journal Article
Rational design of a potent macrocyclic peptide inhibitor targeting the PD-1/PD-L1 protein-protein interaction
Miao, Qi, Zhang, Wanheng, Zhang, Kuojun, Li, He, Zhu, Jidong, Jiang, Sheng
Published in RSC advances (01.07.2021)
Published in RSC advances (01.07.2021)
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