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Published in Angewandte Chemie International Edition (12.03.2018)
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605 Systemically administered HER2-targeted ISACs provoke a rapid, local response that engages the innate and adaptive arms of the immune system to eradicate tumors in preclinical models
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784 BDC-2034: discovery of a CEA-targeting immune-stimulating antibody conjugate (ISAC) for solid tumors
Mallet, William, Gadkari, Rishali, Pearson, Cecelia, Torrez Dulgeroff, Laughing Bear, Luo, Angela, Luo, AAngela Luondrew, Melrose, Jennifer, Nolin, Jess, Lee, Arthur, Zhou, Matthew, Anand, Puneet, Sarma, Ganapathy, Henning, Karla, Blum, Lisa, Chapin, Steven, Bogaert, Liz, Ackerman, Shelley, Kudirka, Romas, Shen, Yuyi, Husain, Amreen, Perez, Edith, Kowanetz, Marcin, Alonso, Michael, Safina, Brian, Dornan, David
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Potential of Fatty Acid Amide Hydrolase (FAAH), Monoacylglycerol Lipase (MAGL), and Diacylglycerol Lipase (DAGL) Enzymes as Targets for Obesity Treatment: A Narrative Review
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Published in Pharmaceuticals (Basel, Switzerland) (17.12.2021)
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N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
Zhou, Matthew N., Delaveris, Corleone S., Kramer, Jessica R., Kenkel, Justin A., Engleman, Edgar G., Bertozzi, Carolyn R.
Published in Angewandte Chemie (12.03.2018)
Published in Angewandte Chemie (12.03.2018)
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Journal Article
N-carboxyanhydride polymerization of glycopolypeptides that activate antigen presenting cells through Dectin-1 and -2
Zhou, Matthew N., Delaveris, Corleone S., Kramer, Jessica R., Kenkel, Justin A., Engleman, Edgar G., Bertozzi, Carolyn R.
Published in Angewandte Chemie International Edition (21.02.2018)
Published in Angewandte Chemie International Edition (21.02.2018)
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암 치료에 유용한 하나 이상의 8-HET-2-아미노벤자제핀유도체에 대한 접합에 의해 연결된 항-CEA 항체를 포함하는 면역접합체
SAFINA BRIAN, LEE ARTHUR, ALONSO MICHAEL N, ACKERMAN SHELLEY ERIN, KOWANETZ MARCIN, MALLET WILLIAM, KUDIRKA ROMAS, DORNAN DAVID, ZHOU MATTHEW
Year of Publication 10.08.2023
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Year of Publication 10.08.2023
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Year of Publication 10.08.2023
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Year of Publication 18.03.2022
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Year of Publication 27.02.2020
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Year of Publication 27.02.2020
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Abstract 2911: The CEA-targeted ISAC, BDC-2034, shows preclinical efficacy associated with innate immune activation, phagocytosis, and myeloid reprogramming
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Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 4252: PD-L1-targeted ISAC combines myeloid cell activation, immune-checkpoint inhibition and ADCP to improve anti-tumor efficacy over anti-PD-L1 antibodies in preclinical models
Kenkel, Justin A., Gadkari, Rishali, Ho, Po Y., Blum, Lisa K., Kudirka, Romas, Henning, Karla A., Mallet, William G., Melrose, Jennifer E., Sarma, Ganapathy, Chapin, Steven J., Zhou, Matthew, Deol, Suprit, Kreder, Cindy, Shen, Yuyi, Hug, Bruce, Anand, Puneet, Lee, Arthur, Li, Hai, Ackerman, Shelley E., Safina, Brian S., Dornan, David, Alonso, Michael N., Kowanetz, Marcin
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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